BDBM22339 (5E)-5-[(4-nitrophenyl)methylidene]-2-(1,3-thiazol-2-ylamino)-4,5-dihydro-1,3-thiazol-4-one::thiazolidinone derivative, 4

SMILES [O-][N+](=O)c1ccc(C=C2SC(Nc3nccs3)=NC2=O)cc1

InChI Key InChIKey=MINTVBBMBYDMCN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 22339   

TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
Aristotle University

LigandPNGBDBM22339((5E)-5-[(4-nitrophenyl)methylidene]-2-(1,3-thiazol...)
Affinity DataIC50: 2.51E+5nMpH: 7.4 T: 2°CAssay Description:The tested compounds were added to the reaction mixture with soybean lipoxygenase. Enzyme reaction was initiated by the addition of sodium linoleate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2008
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Aristotle University

LigandPNGBDBM22339((5E)-5-[(4-nitrophenyl)methylidene]-2-(1,3-thiazol...)
Affinity DataIC50: 1.41E+5nMpH: 8.0 T: 2°CAssay Description:The COX enzyme activities were measured using the COX Inhibitor Screening Assay kit provided by Cayman (Cayman, Chemical Co., Ann Arbor, MI). The ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2008
Entry Details Article
PubMed