BDBM153389 2-(1-Methyl-4,5-dibromo-1H-pyrrole-2-carbonyl-N-(furan-2-yl))hydrazine carboxamide (4s)

SMILES Cn1c(Br)c(Br)cc1C(=O)NNC(=O)Nc1ccco1

InChI Key InChIKey=JEKMXKBOWIPBPT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 153389   

Target72 kDa type IV collagenase(Human)
University of Kwazulu-Nata

LigandPNGBDBM153389(2-(1-Methyl-4,5-dibromo-1H-pyrrole-2-carbonyl-N-(f...)
Affinity DataIC50: 6.03E+4nMpH: 8.5 T: 2°CAssay Description:The synthesized compounds were assayed for the inhibitory activities against MMP-2 in 96-well microtiter plates using succinylated gelatin as the sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
University of Kwazulu-Nata

LigandPNGBDBM153389(2-(1-Methyl-4,5-dibromo-1H-pyrrole-2-carbonyl-N-(f...)
Affinity DataIC50: 8.42E+4nMpH: 8.0 T: 2°CAssay Description:The synthesized compounds were assayed for the inhibitory activities against MMP-12 in 96-well microtiter plates using thiopeptolide as the substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details Article
PubMed