BDBM153387 2-(1-Methyl-4,5-dibromo-1H-pyrrole-2-carbonyl)-N-(3,4,5-trimethoxyphenyl) hydrazine carbothioamide (5t)

SMILES COc1cc(NC(=S)NNC(=O)c2cc(Br)c(Br)n2C)cc(OC)c1OC

InChI Key InChIKey=VBUNYHIMTDBQTN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 153387   

Target72 kDa type IV collagenase(Human)
University of Kwazulu-Nata

LigandPNGBDBM153387(2-(1-Methyl-4,5-dibromo-1H-pyrrole-2-carbonyl)-N-(...)
Affinity DataIC50: 1.92E+4nMpH: 8.5 T: 2°CAssay Description:The synthesized compounds were assayed for the inhibitory activities against MMP-2 in 96-well microtiter plates using succinylated gelatin as the sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
University of Kwazulu-Nata

LigandPNGBDBM153387(2-(1-Methyl-4,5-dibromo-1H-pyrrole-2-carbonyl)-N-(...)
Affinity DataIC50: 2.38E+4nMpH: 8.0 T: 2°CAssay Description:The synthesized compounds were assayed for the inhibitory activities against MMP-12 in 96-well microtiter plates using thiopeptolide as the substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details Article
PubMed