BDBM150785 1H-Spiro(cyclohexane-1,2-quinazolin)-4(3H)-one (1i)

SMILES O=C1CCC2(CC1)Nc1ccccc1C=N2

InChI Key InChIKey=CIPBCLRTAXQMRP-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 150785   

TargetCathepsin B(Goat)
Kurukshetra University

LigandPNGBDBM150785(1H-Spiro(cyclohexane-1,2-quinazolin)-4(3H)-one (1i...)
Affinity DataKi:  1.50E+4nMpH: 6.0Assay Description:Cathepsin B and H were first activated in the presence of thiol activators at pH 6.0 and pH 7.0, respectively. Then, 15 µL of the enzyme solution was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2015
Entry Details Article
PubMed
TargetCathepsin H(Goat)
Kurukshetra University

LigandPNGBDBM150785(1H-Spiro(cyclohexane-1,2-quinazolin)-4(3H)-one (1i...)
Affinity DataKi:  9.01E+4nMpH: 6.0Assay Description:Cathepsin B and H were first activated in the presence of thiol activators at pH 6.0 and pH 7.0, respectively. Then, 15 µL of the enzyme solution was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2015
Entry Details Article
PubMed