BDBM13431 CHEMBL204336::N-{4-[(2S)-2-{[(tert-butoxy)carbonyl]amino}-2-(methylcarbamoyl)ethyl]phenyl}sulfamic acid::phenylalanine analog 2::sulfamic acid deriv. 2

SMILES CNC(=O)[C@H](Cc1ccc(NS(O)(=O)=O)cc1)NC(=O)OC(C)(C)C

InChI Key InChIKey=SQRHYYPEUFLSML-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 13431   

TargetTyrosine-protein phosphatase non-receptor type 1 [1-298](Human)
Procter & Gamble Pharmaceuticals

LigandPNGBDBM13431(N-{4-[(2S)-2-{[(tert-butoxy)carbonyl]amino}-2-(met...)
Affinity DataIC50: 3.96E+4nMpH: 7.0 T: 2°CAssay Description:The activity of PTP1B enzyme was assayed with DiFMUP as substrate. Hydrolysis of substrate was monitored on a Victor V plate reader (Wallac). Kinetic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2007
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM13431(N-{4-[(2S)-2-{[(tert-butoxy)carbonyl]amino}-2-(met...)
Affinity DataIC50: 3.96E+4nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed