BDBM50208877 2-amino-6-chloropurine::6-Cl-purine (1)::6-chloroguanine::CHEMBL226396

SMILES Nc1nc(Cl)c2[nH]cnc2n1

InChI Key InChIKey=RYYIULNRIVUMTQ-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50208877   

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
East China University of Science and Technology

LigandPNGBDBM50208877(6-Cl-purine (1) | CHEMBL226396 | 2-amino-6-chlorop...)
Affinity DataIC50: 5.97E+4nMpH: 6.5Assay Description:Enzymatic activity of enzyme was evaluated using pNPP assay. Briefly, a reaction mixture (100 µL) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and recom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2014
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
East China University of Science and Technology

LigandPNGBDBM50208877(6-Cl-purine (1) | CHEMBL226396 | 2-amino-6-chlorop...)
Affinity DataIC50: 8.00E+4nMpH: 6.5Assay Description:Enzymatic activity of enzyme was evaluated using pNPP assay. Briefly, a reaction mixture (100 µL) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and recom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2014
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase F(Human)
East China University of Science and Technology

LigandPNGBDBM50208877(6-Cl-purine (1) | CHEMBL226396 | 2-amino-6-chlorop...)
Affinity DataIC50: 8.00E+4nMpH: 6.5Assay Description:Enzymatic activity of enzyme was evaluated using pNPP assay. Briefly, a reaction mixture (100 µL) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and recom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2014
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Human)
East China University of Science and Technology

LigandPNGBDBM50208877(6-Cl-purine (1) | CHEMBL226396 | 2-amino-6-chlorop...)
Affinity DataIC50: 8.00E+4nMpH: 6.5Assay Description:Enzymatic activity of enzyme was evaluated using pNPP assay. Briefly, a reaction mixture (100 µL) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and recom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2014
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
East China University of Science and Technology

LigandPNGBDBM50208877(6-Cl-purine (1) | CHEMBL226396 | 2-amino-6-chlorop...)
Affinity DataIC50: 8.00E+4nMpH: 6.5Assay Description:Enzymatic activity of enzyme was evaluated using pNPP assay. Briefly, a reaction mixture (100 µL) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and recom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2014
Entry Details Article
PubMed
TargetXanthine dehydrogenase/oxidase(Human)
Institute of Biological Chemistry and The Genomics Research Center

Curated by ChEMBL
LigandPNGBDBM50208877(6-Cl-purine (1) | CHEMBL226396 | 2-amino-6-chlorop...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human xanthine oxidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)TBA
LigandPNGBDBM50208877(6-Cl-purine (1) | CHEMBL226396 | 2-amino-6-chlorop...)
Affinity DataIC50: 5nMAssay Description:Inhibition of dipeptidyl peptidase 4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article