38 articles for thisTarget
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Recent discovery of non-nucleobase thymidine phosphorylase inhibitors targeting cancer.
Aimst University
Quinazolines and quinazolinones as ubiquitous structural fragments in medicinal chemistry: An update on the development of synthetic methods and pharmacological diversification.
Quaid-I-Azam University
Discovery of mixed type thymidine phosphorylase inhibitors endowed with antiangiogenic properties: synthesis, pharmacological evaluation and molecular docking study of 2-thioxo-pyrazolo[1,5-a][1,3,5]triazin-4-ones. Part II.
National University of Singapore
Fragment-based approach to the design of 5-chlorouracil-linked-pyrazolo[1,5-a][1,3,5]triazines as thymidine phosphorylase inhibitors.
National University of Singapore
Design of novel potent inhibitors of human uridine phosphorylase-1: synthesis, inhibition studies, thermodynamics, and in vitro influence on 5-fluorouracil cytotoxicity.
Pontifical Catholic University of Rio Grande Do Sul
A structure-activity relationship study of 1,2,4-triazolo[1,5-a][1,3,5]triazin-5,7-dione and its 5-thioxo analogues on anti-thymidine phosphorylase and associated anti-angiogenic activities.
National University of Singapore
Synthesis of pyrazolo[1,5-a][1,3,5]triazine derivatives as inhibitors of thymidine phosphorylase.
National University of Singapore
Structural diversity of nucleoside phosphonic acids as a key factor in the discovery of potent inhibitors of rat T-cell lymphoma thymidine phosphorylase.
Academy of Sciences of The Czech Republic
Aminoimidazolylmethyluracil analogues as potent inhibitors of thymidine phosphorylase and their bioreductive nitroimidazolyl prodrugs.
University of Manchester
Identification of a novel class of inhibitor of human and Escherichia coli thymidine phosphorylase by in silico screening.
University of Manchester
Design of novel N-(2,4-dioxo-1,2,3,4-tetrahydro-thieno[3,2-d]pyrimidin-7-yl)-guanidines as thymidine phosphorylase inhibitors, and flexible docking to a homology model.
Attenuon
8-Aza-7,9-dideazaxanthine acyclic nucleoside phosphonate inhibitors of thymidine phosphorylase.
Academy of Sciences of The Czech Republic
The role of phosphate in the action of thymidine phosphorylase inhibitors: Implications for the catalytic mechanism.
University At Buffalo
Xanthine oxidase-activated prodrugs of thymidine phosphorylase inhibitors.
University of Manchester
Synthesis and evaluation of multisubstrate bicyclic pyrimidine nucleoside inhibitors of human thymidine phosphorylase.
Attenuon
5'-O-tritylinosine and analogues as allosteric inhibitors of human thymidine phosphorylase.
Instituto De QuíMica MéDica (Csic)
Synthesis and enzymatic evaluation of xanthine oxidase-activated prodrugs based on inhibitors of thymidine phosphorylase.
University of Manchester
Potential tumor-selective nitroimidazolylmethyluracil prodrug derivatives: inhibitors of the angiogenic enzyme thymidine phosphorylase.
University of Manchester
Structure-activity relationship of biaryl acylsulfonamide analogues on the human EP(3) prostanoid receptor.
Merck Frosst Centre For Therapeutic Research
Novel nonsubstrate inhibitors of human thymidine phosphorylase, a potential target for tumor-dependent angiogenesis.
Istituto Di Genetica Biochimica Ed Evoluzionistica
Design of Novel Inhibitors of Human Thymidine Phosphorylase: Synthesis, Enzyme Inhibition, in Vitro Toxicity, and Impact on Human Glioblastoma Cancer.
Universidade Federal Do Pampa
Synthesis and biological evaluation of novel oxadiazole derivatives: a new class of thymidine phosphorylase inhibitors as potential anti-tumor agents.
Institute of Information Technology
Fluorophosphonylated nucleoside derivatives as new series of thymidine phosphorylase multisubstrate inhibitors.
University of Caen Normandie
Structure-activity relationship of 2,4,5-trioxoimidazolidines as inhibitors of thymidine phosphorylase.
University of Manchester
Schiff bases of 3-formylchromone as thymidine phosphorylase inhibitors.
University of Karachi
Biotransformation of (-)-ambrox by cell suspension cultures of Actinidia deliciosa.
University of Karachi
Synthesis and biological activity of 5-fluoro-2',3'-dideoxy-3'-fluorouridine and its 5'-phosphate.
TBA
1,3,5-Triazines: A promising scaffold for anticancer drugs development.
University of Palermo
Synthesis and biological evaluation of novel 1-(aryl-aldehyde-oxime)uracil derivatives as a new class of thymidine phosphorylase inhibitors.
Yunnan University
Rational design of bis-indolylmethane-oxadiazole hybrids as inhibitors of thymidine phosphorylase.
Imam Abdulrahman Bin Faisal University
Tetrahydrophenanthridinones and tetrahydrocyclopentaquinolinones as PARP and tubulin polymerization inhibitors
Janssen Pharmaceutica
Non-amidic linkers with branched termini as CGRP receptor antagonists
Merck Sharp & Dohme
Characterization and function of the bovine kidney epithelial angiotensin receptor subtype 4 using angiotensin IV and divalinal angiotensin IV as receptor ligands.
Washington State University
Characterization of a 5-hydroxytryptamine receptor in mouse neuroblastoma N18TG2 cells.
University of Pennsylvania