Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50018753
TargetHepatocyte growth factor receptor(Human)
Kurukshetra University

Curated by ChEMBL
LigandPNGBDBM50612045(CHEMBL5286745)
Affinity DataIC50: 0.220nMAssay Description:Inhibition of human MET H1094Y mutant incubated for 1 hrs by ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Kurukshetra University

Curated by ChEMBL
LigandPNGBDBM50612045(CHEMBL5286745)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human MET Y1235D mutant incubated for 1 hrs by ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Kurukshetra University

Curated by ChEMBL
LigandPNGBDBM50608645(CHEMBL4535844)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of Escherichia coli DNA gyrase supercoiling activity by Microplate Assay kit methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Kurukshetra University

Curated by ChEMBL
LigandPNGBDBM50612044(CHEMBL4470336)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of Escherichia coli DNA gyrase supercoiling activity by Microplate Assay kit methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Kurukshetra University

Curated by ChEMBL
LigandPNGBDBM50612045(CHEMBL5286745)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of human MET incubated for 30 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Kurukshetra University

Curated by ChEMBL
LigandPNGBDBM50612045(CHEMBL5286745)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of human MET M1250T mutant incubated for 1 hrs by ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Kurukshetra University

Curated by ChEMBL
LigandPNGBDBM50612045(CHEMBL5286745)
Affinity DataIC50: 65nMAssay Description:Inhibition of human MET L1195V mutant incubated for 1 hrs by ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Kurukshetra University

Curated by ChEMBL
LigandPNGBDBM50612045(CHEMBL5286745)
Affinity DataIC50: 81nMAssay Description:Inhibition of human MET D1228H mutant incubated for 1 hrs by ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(malaria parasite P. vivax)
Kurukshetra University

Curated by ChEMBL
LigandPNGBDBM50612056(CHEMBL5270166)
Affinity DataIC50: 94nMAssay Description:Inhibition of Plasmodium vivax dihydrofolate reductase measured after 48 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Kurukshetra University

Curated by ChEMBL
LigandPNGBDBM50612046(CHEMBL5276696)
Affinity DataIC50: 110nMAssay Description:Inhibition of c-Met (unknown origin) incubated for 1 hrs in presence of ATP by ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Kurukshetra University

Curated by ChEMBL
LigandPNGBDBM50612046(CHEMBL5276696)
Affinity DataIC50: 190nMAssay Description:Inhibition of human VEGFR2 (unknown origin) incubated for 1 hrs in presence of ATP by ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetSimilar to alpha-tubulin isoform 1(Bovine)
Kurukshetra University

Curated by ChEMBL
LigandPNGBDBM50612054(CHEMBL4749493)
Affinity DataIC50: 660nMAssay Description:Inhibition of bovine brain tubulin polymerization incubated for 20 mins in presence of GTPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Kurukshetra University

Curated by ChEMBL
LigandPNGBDBM50612042(CHEMBL5285408)
Affinity DataIC50: 970nMAssay Description:Inhibition of human Topoisomerase 2 incubated for 30 mins by ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetSimilar to alpha-tubulin isoform 1(Bovine)
Kurukshetra University

Curated by ChEMBL
LigandPNGBDBM50612055(CHEMBL5274633)
Affinity DataIC50: 970nMAssay Description:Inhibition of bovine brain tubulin polymerization incubated for 20 mins in presence of GTPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Kurukshetra University

Curated by ChEMBL
LigandPNGBDBM50612043(CHEMBL5269118)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human Topoisomerase 2 incubated for 30 mins by ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetSimilar to alpha-tubulin isoform 1(Bovine)
Kurukshetra University

Curated by ChEMBL
LigandPNGBDBM50005480(combretastin A4 | CHEMBL67 | 2-Methoxy-5-[2-(3,4,5...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of bovine brain tubulin polymerization incubated for 20 mins in presence of GTPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Kurukshetra University

Curated by ChEMBL
LigandPNGBDBM50457206(CHEMBL4216765)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of EGFR (unknown origin) infected in insect sf9 cells incubated for 1 hrs in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Kurukshetra University

Curated by ChEMBL
LigandPNGBDBM50612053(CHEMBL5287053)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of EGFR (unknown origin) infected in insect sf9 cells incubated for 1 hrs in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetThymidine phosphorylase(Human)
Kurukshetra University

Curated by ChEMBL
LigandPNGBDBM50612050(CHEMBL5282306)
Affinity DataIC50: 4.39E+4nMAssay Description:Inhibition of Thymidine phosphorylase (unknown origin) incubated for 14 days by CAM assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetThymidine phosphorylase(Human)
Kurukshetra University

Curated by ChEMBL
LigandPNGBDBM50612051(CHEMBL5284678)
Affinity DataIC50: 4.39E+4nMAssay Description:Inhibition of Thymidine phosphorylase (unknown origin) incubated for 14 days by CAM assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetThymidine phosphorylase(Human)
Kurukshetra University

Curated by ChEMBL
LigandPNGBDBM50612052(CHEMBL5280134)
Affinity DataIC50: 4.39E+4nMAssay Description:Inhibition of Thymidine phosphorylase (unknown origin) incubated for 14 days by CAM assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetThymidine phosphorylase(Human)
Kurukshetra University

Curated by ChEMBL
LigandPNGBDBM50612049(CHEMBL2002786)
Affinity DataIC50: 4.39E+4nMAssay Description:Inhibition of Thymidine phosphorylase (unknown origin) incubated for 14 days by CAM assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetThymidine phosphorylase(Human)
Kurukshetra University

Curated by ChEMBL
LigandPNGBDBM50612048(CHEMBL5272184)
Affinity DataIC50: 4.39E+4nMAssay Description:Inhibition of Thymidine phosphorylase (unknown origin) incubated for 14 days by CAM assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetThymidine phosphorylase(Human)
Kurukshetra University

Curated by ChEMBL
LigandPNGBDBM50612047(CHEMBL5273439)
Affinity DataIC50: 4.39E+4nMAssay Description:Inhibition of Thymidine phosphorylase (unknown origin) incubated for 14 days by CAM assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed