BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.1M data for 1.3M Compounds and 9.6K Targets. Of those, 1.5M data for 698K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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To help with training and testing AI and other models, BindingDB downloads and search results now provide the publication date and BindingDB curation date of each measurement.

21 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Activation of the¿-Aminobutyric Acid Type B (GABA(B)) Receptor by Agonists and Positive Allosteric Modulators.EBI
Purdue University
Evaluation of difluoromethyl ketones as agonists of the¿-aminobutyric acid type B (GABAB) receptor.EBI
Purdue University
Partial GABAA receptor agonists. Synthesis and in vitro pharmacology of a series of nonannulated analogs of 4,5,6,7-tetrahydroisoxazolo[5,4-c]pyridin-3-ol.EBI
Royal Danish School of Pharmacy
3-Thienyl- and 3-furylaminobutyric acids. Synthesis and binding GABAB receptor studies.EBI
Laboratoire De Pharmacie Chimique, Facult�
Synthesis and biochemical evaluation of baclofen analogues locked in the baclofen solid-state conformation.EBI
Centre De Neurochimie Du Cnrs
GABA agonists and uptake inhibitors. Synthesis, absolute stereochemistry, and enantioselectivity of (R)-(-)- and (S)-(+)-homo-beta-proline.EBI
Royal Danish School of Pharmacy
Synthesis and pharmacological evaluation of gamma-aminobutyric acid analogues. New ligand for GABAB sites.EBI
TBA
Aminomethyl-2,6-difluorophenols as a novel class of increased lipophilicity GABA(C) receptor antagonists.EBI
The University of Sydney
 
The first selective antagonist for a GABAC receptorEBI
TBA
 
A study of 3-amino-N-hydroxypropanesulfonamide derivatives as potential GABAB agonists and their fragmentation to 3-aminopropanesulfinic acidEBI
TBA
Novel Cyclic Phosphinic Acids as GABAC ρ Receptor Antagonists: Design, Synthesis, and PharmacologyEBI
TBA
 
Synthesis and resolution of β-(aminomethyl)-4-chlorobenzeneethanesulfinic acid a potent gabaB receptor ligandEBI
TBA
 
Biological activity of 3-aminopropyl (methyl) phosphinic acid, a potent and selective GABAB agonist with CNS activityEBI
TBA
6-Aryl-quinazolines as novel GABAEBI
Chemical Works of Gedeon Richter
Alkyne-Bridged α-Conotoxin Vc1.1 Potently Reverses Mechanical Allodynia in Neuropathic Pain Models.EBI
Monash University
Targeting of N-Type Calcium Channels via GABAEBI
Beijing Institute of Biotechnology
Synthesis and pharmacology of the baclofen homologues 5-amino-4-(4-chlorophenyl)pentanoic acid and the R- and S-enantiomers of 5-amino-3-(4-chlorophenyl)pentanoic acid.EBI
The Royal Danish School of Pharmacy
Discovery of a Negative Allosteric Modulator of GABAB Receptors.EBI
Chinese Academy of Sciences
Phosphinic acid analogues of GABA. 1. New potent and selective GABAB agonists.EBI
Ciba-Geigy
Syntheses and optimization of new GS39783 analogues as positive allosteric modulators of GABA B receptors.EBI
Novartis Institutes For Biomedical Research
Synthesis and activity of 5-(aminomethylene)-1,3-cyclohexanediones: enolic analogues of gamma-aminobutyric acid.EBI
TBA