Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50035975
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Rat)
Laboratoire De Pharmacie Chimique, Facult�

Curated by ChEMBL
LigandPNGBDBM24183(4-amino-n-[2,3-3H]butyric acid | cid_119 | Gamma-A...)
Affinity DataIC50: 40nMAssay Description:Inhibition of [3H]baclofen binding to rat gamma-aminobutyric acid type B receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Rat)
Laboratoire De Pharmacie Chimique, Facult�

Curated by ChEMBL
LigandPNGBDBM24182(4-amino-3-(4-chlorophenyl)butanoic acid | CHEMBL70...)
Affinity DataIC50: 330nMAssay Description:Inhibition of [3H]baclofen binding to rat gamma-aminobutyric acid type B receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Rat)
Laboratoire De Pharmacie Chimique, Facult�

Curated by ChEMBL
LigandPNGBDBM24182(4-amino-3-(4-chlorophenyl)butanoic acid | CHEMBL70...)
Affinity DataIC50: 330nMAssay Description:Inhibition of [3H]baclofen binding to rat gamma-aminobutyric acid type B receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Rat)
Laboratoire De Pharmacie Chimique, Facult�

Curated by ChEMBL
LigandPNGBDBM50007118(CHEMBL87482 | 4-Amino-3-(5-chloro-thiophen-2-yl)-b...)
Affinity DataIC50: 610nMAssay Description:Inhibition of [3H]baclofen binding to rat gamma-aminobutyric acid type B receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Rat)
Laboratoire De Pharmacie Chimique, Facult�

Curated by ChEMBL
LigandPNGBDBM50007121(CHEMBL83245 | 4-Amino-3-(2-chloro-phenyl)-butyric ...)
Affinity DataIC50: 800nMAssay Description:Inhibition of [3H]baclofen binding to rat gamma-aminobutyric acid type B receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Rat)
Laboratoire De Pharmacie Chimique, Facult�

Curated by ChEMBL
LigandPNGBDBM50368295(CHEMBL301492)
Affinity DataIC50: 1.33E+3nMAssay Description:Inhibition of [3H]baclofen binding to rat gamma-aminobutyric acid type B receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Rat)
Laboratoire De Pharmacie Chimique, Facult�

Curated by ChEMBL
LigandPNGBDBM50007107(CHEMBL86144 | 4-Amino-3-(5-methyl-thiophen-2-yl)-b...)
Affinity DataIC50: 1.34E+3nMAssay Description:Inhibition of [3H]baclofen binding to rat gamma-aminobutyric acid type B receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Rat)
Laboratoire De Pharmacie Chimique, Facult�

Curated by ChEMBL
LigandPNGBDBM50007108(CHEMBL314177 | 4-Amino-3-(5-bromo-thiophen-2-yl)-b...)
Affinity DataIC50: 1.86E+3nMAssay Description:Inhibition of [3H]baclofen binding to rat gamma-aminobutyric acid type B receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Rat)
Laboratoire De Pharmacie Chimique, Facult�

Curated by ChEMBL
LigandPNGBDBM50007117(CHEMBL315476 | 4-Amino-3-thiophen-2-yl-butyric aci...)
Affinity DataIC50: 9.72E+3nMAssay Description:Inhibition of [3H]baclofen binding to rat gamma-aminobutyric acid type B receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Rat)
Laboratoire De Pharmacie Chimique, Facult�

Curated by ChEMBL
LigandPNGBDBM50007109(CHEMBL315789 | 4-Amino-3-(3-chloro-phenyl)-butyric...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of [3H]baclofen binding to rat gamma-aminobutyric acid type B receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Rat)
Laboratoire De Pharmacie Chimique, Facult�

Curated by ChEMBL
LigandPNGBDBM50007113(CHEMBL87856 | 4-Amino-3-thiophen-3-yl-butyric acid)
Affinity DataIC50: 2.09E+4nMAssay Description:Inhibition of [3H]baclofen binding to rat gamma-aminobutyric acid type B receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Rat)
Laboratoire De Pharmacie Chimique, Facult�

Curated by ChEMBL
LigandPNGBDBM50007110(CHEMBL315950 | 4-Amino-3-(4-bromo-thiophen-2-yl)-b...)
Affinity DataIC50: 3.91E+4nMAssay Description:Inhibition of [3H]baclofen binding to rat gamma-aminobutyric acid type B receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Rat)
Laboratoire De Pharmacie Chimique, Facult�

Curated by ChEMBL
LigandPNGBDBM50007111(CHEMBL85948 | 4-Amino-3-(4-chloro-thiophen-2-yl)-b...)
Affinity DataIC50: 4.53E+4nMAssay Description:Inhibition of [3H]baclofen binding to rat gamma-aminobutyric acid type B receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Rat)
Laboratoire De Pharmacie Chimique, Facult�

Curated by ChEMBL
LigandPNGBDBM50007119(CHEMBL53073 | 4-Amino-3-phenyl-butyric acid)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of [3H]baclofen binding to rat gamma-aminobutyric acid type B receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Rat)
Laboratoire De Pharmacie Chimique, Facult�

Curated by ChEMBL
LigandPNGBDBM50007120(CHEMBL315440 | 4-Amino-3-(4-hydroxy-phenyl)-butyri...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of [3H]baclofen binding to rat gamma-aminobutyric acid type B receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Rat)
Laboratoire De Pharmacie Chimique, Facult�

Curated by ChEMBL
LigandPNGBDBM50007114(CHEMBL85880 | 4-Amino-3-furan-2-yl-butyric acid)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of [3H]baclofen binding to rat gamma-aminobutyric acid type B receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Rat)
Laboratoire De Pharmacie Chimique, Facult�

Curated by ChEMBL
LigandPNGBDBM50007112(CHEMBL83011 | 4-Amino-3-(5-methyl-furan-2-yl)-buty...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of [3H]baclofen binding to rat gamma-aminobutyric acid type B receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Rat)
Laboratoire De Pharmacie Chimique, Facult�

Curated by ChEMBL
LigandPNGBDBM50007116(CHEMBL313323 | 4-Amino-3-(3-methyl-thiophen-2-yl)-...)
Affinity DataIC50: 1.24E+5nMAssay Description:Inhibition of [3H]baclofen binding to rat gamma-aminobutyric acid type B receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed