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BindingDB contains 3.1M data for 1.3M Compounds and 9.6K Targets. Of those, 1.5M data for 698K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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12 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Ras inhibition via direct Ras binding--is there a path forward?EBI
Genentech
Synthesis and antitumor activity of new benzoheterocyclic derivatives of distamycin A.EBI
University of Ferrara
Design, synthesis and biological activity of a pyrrolo [2,1-c][1,4]benzodiazepine (PBD)-distamycin hybrid.EBI
University of Ferrara
 
Synthesis and evaluation of pyrazolo[3,4-b]quinoline ribofuranosides and their derivatives as inhibitors of oncogenic RasEBI
TBA
A decade of approved first-in-class small molecule orphan drugs: Achievements, challenges and perspectives.EBI
China Pharmaceutical University
Targeting mutated GTPase KRAS in tumor therapies.EBI
Sun Yat-Sen University
Zinc enzymes in medicinal chemistry.EBI
Hefei University of Technology
Targeting KRAS mutant cancers by preventing signaling transduction in the MAPK pathway.EBI
Massachusetts College of Pharmacy and Health Sciences University
Fragment-to-Lead Medicinal Chemistry Publications in 2018.EBI
Frontier Medicines
C-terminal modifications of histidyl-N-benzylglycinamides to give improved inhibition of Ras farnesyltransferase, cellular activity, and anticancer activity in mice.EBI
Warner-Lambert
Ophirapstanol trisulfate, a new biologically active steroid sulfate from the deep water marine sponge Topsentia ophiraphidites.EBI
Harbor Branch Oceanographic Institution
RET inhibitors, pharmaceutical compositions and uses thereofBDB
Sunshine Lake Pharma Co.