Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50042134
TargetGTPase HRas(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50421182(CHEMBL2086797)
Affinity DataKd:  2.80E+4nMAssay Description:Binding affinity to His6-tagged HRas expressed in Escherichia coli (BL21) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetGTPase HRas(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50421182(CHEMBL2086797)
Affinity DataKd:  1.58E+5nMAssay Description:Binding affinity to His6-tagged HRas-GDP expressed in Escherichia coli (BL21) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetGTPase NRas(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50421183(CHEMBL2086789)
Affinity DataIC50: 500nMAssay Description:Inhibition of N-Ras expressed in Escherichia coli using [3H]GDP and [3H]GTP assessed as inhibition of intrinsic nucleotide exchange by scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetSon of sevenless homolog 1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50421182(CHEMBL2086797)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition to His6-tagged Sos1 catalytic domain-mediated nucleotide exchange by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed