33 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Data
Article Title
Organization
Identification of new pyrrolo[2,3-d]pyrimidines as Src tyrosine kinase inhibitors in vitro active against Glioblastoma.
University of Genoa
Novel biguanide-based derivatives scouted as TAAR1 agonists: Synthesis, biological evaluation, ADME prediction and molecular docking studies.
University of Genoa
Design and synthesis of 4,5,6,7-tetrahydro-1H-1,2-diazepin-7-one derivatives as a new series of Phosphodiesterase 4 (PDE4) inhibitors.
University of Genoa
Quinazolinedione SIRT6 inhibitors sensitize cancer cells to chemotherapeutics.
University of Genoa
In silico evaluation of human small heat shock protein HSP27: homology modeling, mutation analyses and docking studies.
University of Genoa
Synthesis, biological activities and pharmacokinetic properties of new fluorinated derivatives of selective PDE4D inhibitors.
University of Genoa
Synthesis, biological evaluation, and molecular modeling of new 3-(cyclopentyloxy)-4-methoxybenzaldehyde O-(2-(2,6-dimethylmorpholino)-2-oxoethyl) Oxime (GEBR-7b) related phosphodiesterase 4D (PDE4D) inhibitors.
University of Genoa
Synthesis, structural characterization and effect on human granulocyte intracellular cAMP levels of abscisic acid analogs.
University of Genoa
Synthesis of 2,6-disubstituted benzylamine derivatives as reversible selective inhibitors of copper amine oxidases.
University of Genoa
(+)-Laburnamine, a natural selective ligand and partial agonist for theα4β2 nicotinic receptor subtype.
University of Genoa
Vascular endothelial growth factor (VEGF) receptors: drugs and new inhibitors.
University of Genoa
2-Phenyl-2,3-dihydro-1H-imidazo[1,2-b]pyrazole derivatives: new potent inhibitors of fMLP-induced neutrophil chemotaxis.
University of Genoa
Alkylamino derivatives of 4-aminomethylpyridine as inhibitors of copper-containing amine oxidases.
University of Genoa
Structure-based design, parallel synthesis, structure-activity relationship, and molecular modeling studies of thiocarbamates, new potent non-nucleoside HIV-1 reverse transcriptase inhibitor isosteres of phenethylthiazolylthiourea derivatives.
University of Genoa
Synthesis, molecular modeling studies, and pharmacological activity of selective A(1) receptor antagonists.
University of Genoa
Synthesis of new 5,6-dihydrobenzo[h]quinazoline 2,4-diamino substituted and antiplatelet/antiphlogistic activities evaluation.
University of Genoa
Homology modeling in tandem with 3D-QSAR analyses: a computational approach to depict the agonist binding site of the human CB2 receptor.
University of Genoa
Quinolizidinyl derivatives of bi- and tricyclic systems as potent inhibitors of acetyl- and butyrylcholinesterase with potential in Alzheimer's disease.
University of Genoa
New selective phosphodiesterase 4D inhibitors differently acting on long, short, and supershort isoforms.
University of Genoa
Thioxanthenone-based derivatives as multitarget therapeutic leads for Alzheimer's disease.
University of Genoa
Discovery of novel VX-809 hybrid derivatives as F508del-CFTR correctors by molecular modeling, chemical synthesis and biological assays.
University of Genoa
Ellagic acid a multi-target bioactive compound for drug discovery in CNS? A narrative review.
University of Genoa
Further SAR studies on bicyclic basic merbarone analogues as potent antiproliferative agents.
University of Genoa
Parallel synthesis, molecular modelling and further structure-activity relationship studies of new acylthiocarbamates as potent non-nucleoside HIV-1 reverse transcriptase inhibitors.
University of Genoa
Thiocarbamates as non-nucleoside HIV-1 reverse transcriptase inhibitors. Part 2: Parallel synthesis, molecular modelling and structure-activity relationship studies on analogues of O-(2-phenylethyl)-N-phenylthiocarbamate.
University of Genoa
Parallel one-pot synthesis and structure-activity relationship study of symmetric formimidoester disulfides as a novel class of potent non-nucleoside HIV-1 reverse transcriptase inhibitors.
University of Genoa
Synthesis and in vitro antiplatelet activity of new 4-(1-piperazinyl)coumarin derivatives. Human platelet phosphodiesterase 3 inhibitory properties of the two most effective compounds described and molecular modeling study on their interactions with phosphodiesterase 3A catalytic site.
University of Genoa
SIRT6 inhibitors with salicylate-like structure show immunosuppressive and chemosensitizing effects.
University of Genoa
Synthesis, biological evaluation and molecular modeling of novel azaspiro dihydrotriazines as influenza virus inhibitors targeting the host factor dihydrofolate reductase (DHFR).
University of Genoa
Rational design, chemical synthesis and biological evaluation of novel biguanides exploring species-specificity responsiveness of TAAR1 agonists.
University of Genoa
Synthesis and biological evaluation of novel thiazole- VX-809 hybrid derivatives as F508del correctors by QSAR-based filtering tools.
University of Genoa