Compile Data Set for Download or QSAR
Report error Found 77 Enz. Inhib. hit(s) with all data for entry = 50019577
TargetCholinesterase(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50620646(CHEMBL5422760)
Affinity DataIC50: 7nMAssay Description:Inhibition of human recombinant BChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by DTNB reag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 17nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by DTNB reag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholinesterase(Electric eel)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 20nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by DTNB reagent b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetCholinesterase(Horse)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50620646(CHEMBL5422760)
Affinity DataIC50: 88nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by DTNB reagent ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50620655(CHEMBL5405496)
Affinity DataIC50: 120nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by DTNB reagent b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetCholinesterase(Horse)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50620651(CHEMBL5419364)
Affinity DataIC50: 140nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by DTNB reagent ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50620660(CHEMBL5438801)
Affinity DataIC50: 140nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by DTNB reagent b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetCholinesterase(Horse)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50620666(CHEMBL5436261)
Affinity DataIC50: 150nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by DTNB reagent ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetCholinesterase(Horse)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50620654(CHEMBL5415210)
Affinity DataIC50: 150nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by DTNB reagent ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetCholinesterase(Horse)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50620648(CHEMBL5431870)
Affinity DataIC50: 160nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by DTNB reagent ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50620646(CHEMBL5422760)
Affinity DataIC50: 180nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by DTNB reagent b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetCholinesterase(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50620660(CHEMBL5438801)
Affinity DataIC50: 300nMAssay Description:Inhibition of human recombinant BChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by DTNB reag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetCholinesterase(Horse)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50620660(CHEMBL5438801)
Affinity DataIC50: 370nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by DTNB reagent ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetCholinesterase(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50620651(CHEMBL5419364)
Affinity DataIC50: 710nMAssay Description:Inhibition of human recombinant BChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by DTNB reag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetAmyloid-beta precursor protein(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromone;...)
Affinity DataIC50: 820nMAssay Description:Inhibition of amyloid beta 40 peptide (unknown origin) aggregation incubated for 2 hr by ThT fluorescence based spectrofluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetAmyloid-beta precursor protein(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50613758(CHEMBL5286183)
Affinity DataIC50: 840nMAssay Description:Inhibition of amyloid beta 40 peptide (unknown origin) aggregation incubated for 2 hr by ThT fluorescence based spectrofluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetCholinesterase(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50620648(CHEMBL5431870)
Affinity DataIC50: 900nMAssay Description:Inhibition of human recombinant BChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by DTNB reag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetCholinesterase(Horse)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50620657(CHEMBL5440445)
Affinity DataIC50: 960nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by DTNB reagent ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetCholinesterase(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50620666(CHEMBL5436261)
Affinity DataIC50: 990nMAssay Description:Inhibition of human recombinant BChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by DTNB reag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetAmyloid-beta precursor protein(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50620665(CHEMBL5422668)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of amyloid beta 40 peptide (unknown origin) aggregation incubated for 2 hr by ThT fluorescence based spectrofluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50620655(CHEMBL5405496)
Affinity DataIC50: 1.75E+3nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by DTNB reag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetMicrotubule-associated protein tau(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50620657(CHEMBL5440445)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of tau (unknown origin) aggregation expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetCholinesterase(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50620654(CHEMBL5415210)
Affinity DataIC50: 1.82E+3nMAssay Description:Inhibition of human recombinant BChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by DTNB reag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50620666(CHEMBL5436261)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by DTNB reagent b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetCholinesterase(Horse)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by DTNB reagent ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetCholinesterase(Horse)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50620655(CHEMBL5405496)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by DTNB reagent ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50620654(CHEMBL5415210)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by DTNB reagent b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetAmyloid-beta precursor protein(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50620648(CHEMBL5431870)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of amyloid beta 40 peptide (unknown origin) aggregation incubated for 2 hr by ThT fluorescence based spectrofluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetAmyloid-beta precursor protein(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50620651(CHEMBL5419364)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of amyloid beta 40 peptide (unknown origin) aggregation incubated for 2 hr by ThT fluorescence based spectrofluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50620666(CHEMBL5436261)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by DTNB reag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetAmyloid-beta precursor protein(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50620652(CHEMBL5425075)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of amyloid beta 40 peptide (unknown origin) aggregation incubated for 2 hr by ThT fluorescence based spectrofluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetAmyloid-beta precursor protein(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50620649(CHEMBL5434938)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of amyloid beta 40 peptide (unknown origin) aggregation incubated for 2 hr by ThT fluorescence based spectrofluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetMicrotubule-associated protein tau(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50620655(CHEMBL5405496)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of tau (unknown origin) aggregation expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50620648(CHEMBL5431870)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by DTNB reagent b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50620651(CHEMBL5419364)
Affinity DataIC50: 3.59E+3nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by DTNB reag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50620648(CHEMBL5431870)
Affinity DataIC50: 4.26E+3nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by DTNB reag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetAmyloid-beta precursor protein(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50620646(CHEMBL5422760)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of amyloid beta 40 peptide (unknown origin) aggregation incubated for 2 hr by ThT fluorescence based spectrofluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetAmyloid-beta precursor protein(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50620662(CHEMBL5427593)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of amyloid beta 40 peptide (unknown origin) aggregation incubated for 2 hr by ThT fluorescence based spectrofluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetAmyloid-beta precursor protein(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50620650(CHEMBL5406305)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of amyloid beta 40 peptide (unknown origin) aggregation incubated for 2 hr by ThT fluorescence based spectrofluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50620657(CHEMBL5440445)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by DTNB reagent b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50620654(CHEMBL5415210)
Affinity DataIC50: 4.75E+3nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by DTNB reag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetCholinesterase(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of human recombinant BChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by DTNB reag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetMicrotubule-associated protein tau(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50620658(CHEMBL5439128)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of tau (unknown origin) aggregation expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50620651(CHEMBL5419364)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by DTNB reagent b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetMicrotubule-associated protein tau(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50620650(CHEMBL5406305)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of tau (unknown origin) aggregation expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetMicrotubule-associated protein tau(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50620652(CHEMBL5425075)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of tau (unknown origin) aggregation expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetAmyloid-beta precursor protein(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50620647(CHEMBL5408406)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of amyloid beta 40 peptide (unknown origin) aggregation incubated for 2 hr by ThT fluorescence based spectrofluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetMicrotubule-associated protein tau(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50620654(CHEMBL5415210)
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of tau (unknown origin) aggregation expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetMicrotubule-associated protein tau(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50620649(CHEMBL5434938)
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of tau (unknown origin) aggregation expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetCholinesterase(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50620655(CHEMBL5405496)
Affinity DataIC50: 7.31E+3nMAssay Description:Inhibition of human recombinant BChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by DTNB reag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
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