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BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 748K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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15 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Leveraging Structure-Based Drug Design to Identify Next-Generation MAT2A Inhibitors, Including Brain-Penetrant and Peripherally Efficacious Leads.EBI
Agios Pharmaceuticals
Discovery of AG-270, a First-in-Class Oral MAT2A Inhibitor for the Treatment of Tumors with Homozygous EBI
Agios Pharmaceuticals
Vorasidenib (AG-881): A First-in-Class, Brain-Penetrant Dual Inhibitor of Mutant IDH1 and 2 for Treatment of Glioma.EBI
Agios Pharmaceuticals
Discovery of AG-120 (Ivosidenib): A First-in-Class Mutant IDH1 Inhibitor for the Treatment of IDH1 Mutant Cancers.EBI
Agios Pharmaceuticals
Bicyclic heterocycles as FGFR4 inhibitorsBDB
Incyte
4-imidazopyridazin-1-yl-benzamides as Btk inhibitorsBDB
Merck Sharp & Dohme
Amino, amido and heterocyclic compounds as modulators of RAGE activity and uses thereofBDB
The State University of New York
Boronic acid derivativesBDB
Merck Patent
Compositions and methods for treating toxoplasmosis, cryptosporidiosis and other apicomplexan protozoan related diseasesBDB
University of Washington
Cardiac glycoside analogs and their use in methods for inhibition of viral infectionBDB
The John Hopkins University
Serendipitous discovery of light-induced (In Situ) formation of an Azo-bridged dimeric sulfonated naphthol as a potent PTP1B inhibitor.BDB
Concordia University of Wisconsin
PyridinonesBDB
Boehringer Ingelheim International
Substituted pyrazolo[1,5-a]pyrazines as mGluR5 receptor modulatorsBDB
Vanderbilt University
Hypophosphorous acid derivatives having antihyperalgic activity and biological applications thereofBDB
Universite Paris Descartes
3-Oxo-2,3-dihydro-1H-indazole-4-carboxamide derivatives as PARP-1 inhibitorsBDB
Nerviano Medical Sciences