BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.1M data for 1.3M Compounds and 9.6K Targets. Of those, 1.5M data for 698K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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To help with training and testing AI and other models, BindingDB downloads and search results now provide the publication date and BindingDB curation date of each measurement.

12 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Inhibiting the deubiquitinating enzymes (DUBs).EBI
Genentech
Discovery of Potent OTUB1/USP8 Dual Inhibitors Targeting Proteostasis in Non-Small-Cell Lung Cancer.EBI
Fudan University
Discovery of USP7 small-molecule allosteric inhibitors.EBI
Medivir
Novel highly selective inhibitors of ubiquitin specific protease 30 (USP30) accelerate mitophagy.EBI
Mitobridge, Inc. (An Astellas)
Discovery of Potent, Selective, and Orally Bioavailable Inhibitors of USP7 with In Vivo Antitumor Activity.EBI
Rapt Therapeutics
Salt of LSD1 inhibitor and a polymorph thereofBDB
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)
DIHYDRO-CYCLOPENTA-ISOQUINOLINE SULFONAMIDES DERIVATIVESBDB
Ucb Biopharma
5-aminolevulinate synthase inhibitors and methods of use thereofBDB
University of South Florida
Substituted nucleosides, nucleotides and analogs thereofBDB
Janssen Biopharma
Indazole compounds as mGluR4 allosteric potentiators, compositions, and methods of treating neurological dysfunctionBDB
Vanderbilt University
1,3,4-thiadiazole compounds and their use in treating cancerBDB
Astrazeneca
Thiazole derivativesBDB
Merck Patent