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Found
18
Enz. Inhib. hit(s) with all data for entry = 50020979
Target
Poly(ADP-ribose) glycohydrolase
(Human)
University of Bologna
Curated by
ChEMBL
Ligand
BDBM371049
(US10239843, Example 156)
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Affinity Data
EC50: 19nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
10/11/2025
Entry Details
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PubMed
PDB
3D Structure (crystal)
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Target
Poly(ADP-ribose) glycohydrolase
(Human)
University of Bologna
Curated by
ChEMBL
Ligand
BDBM370895
(US10239843, Example 2)
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Affinity Data
EC50: 3.90E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
10/11/2025
Entry Details
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PubMed
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Target
DNA repair protein RAD51 homolog 1
(Human)
University of Bologna
Curated by
ChEMBL
Ligand
BDBM50635709
(CHEMBL5527941)
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Affinity Data
Kd: 355nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PDB
In Depth
Date in BDB:
10/11/2025
Entry Details
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PubMed
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Target
DNA repair protein RAD52 homolog
(Human)
University of Bologna
Curated by
ChEMBL
Ligand
BDBM50565809
(CHEMBL1718911)
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Affinity Data
Kd: 2.58E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
10/11/2025
Entry Details
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PubMed
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Target
Poly(ADP-ribose) glycohydrolase
(Human)
University of Bologna
Curated by
ChEMBL
Ligand
BDBM205479
(PDD00017273 (4) | US20230278998, Compound PDD00017...)
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Affinity Data
EC50: 26nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
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PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
10/11/2025
Entry Details
Copy Entry DOI
PubMed
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Target
Serine-protein kinase ATM
(Human)
University of Bologna
Curated by
ChEMBL
Ligand
BDBM418555
(8-(1,3-Dimethylpyrazol-4- yl)-1-[3-fluoro-5-(tride...)
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Affinity Data
IC50: 0.200nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Date in BDB:
10/11/2025
Entry Details
Copy Entry DOI
PubMed
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Target
Serine-protein kinase ATM
(Human)
University of Bologna
Curated by
ChEMBL
Ligand
BDBM50565800
(Azd-1390 | Azd1390 | US20240294545, Compound AZD13...)
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Affinity Data
IC50: 0.780nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Date in BDB:
10/11/2025
Entry Details
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PubMed
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Target
Wee1-like protein kinase
(Human)
University of Bologna
Curated by
ChEMBL
Ligand
BDBM50635712
(CHEMBL5555318)
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Affinity Data
IC50: 0.800nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
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PubMed
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Target
DNA-dependent protein kinase catalytic subunit
(Human)
University of Bologna
Curated by
ChEMBL
Ligand
BDBM50635714
(CHEMBL5558159)
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Affinity Data
IC50: 0.890nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
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PubMed
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Target
DNA-dependent protein kinase catalytic subunit
(Human)
University of Bologna
Curated by
ChEMBL
Ligand
BDBM315715
(US10172859, Example 136 | (S)-[2-Chloro-4- fluoro-...)
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Affinity Data
IC50: 3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
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PC cid
PC sid
Similars
In Depth
Date in BDB:
10/11/2025
Entry Details
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PubMed
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Target
Ubiquitin carboxyl-terminal hydrolase 1
(Human)
University of Bologna
Curated by
ChEMBL
Ligand
BDBM324932
(2-(2-isopropylphenyl)-9-(4- | US10189841, Compound...)
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Affinity Data
IC50: 4.10nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
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PC cid
PC sid
Similars
In Depth
Date in BDB:
10/11/2025
Entry Details
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PubMed
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Target
Poly [ADP-ribose] polymerase 1
(Human)
University of Bologna
Curated by
ChEMBL
Ligand
BDBM50635713
(Azd-9574 | AZD9574)
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Affinity Data
IC50: 5nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
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PubMed
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Target
Ubiquitin carboxyl-terminal hydrolase 1
(Human)
University of Bologna
Curated by
ChEMBL
Ligand
BDBM580031
(US11485736, Compound Table 3.15)
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Affinity Data
IC50: 11nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
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PC cid
PC sid
Similars
In Depth
Date in BDB:
10/11/2025
Entry Details
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PubMed
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Target
Ubiquitin carboxyl-terminal hydrolase 1
(Human)
University of Bologna
Curated by
ChEMBL
Ligand
BDBM50069762
(CHEMBL3182437 | ML323 | US9802904, 87)
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Affinity Data
IC50: 76nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
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CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
10/11/2025
Entry Details
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PubMed
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Target
DNA repair protein RAD52 homolog
(Human)
University of Bologna
Curated by
ChEMBL
Ligand
BDBM50635711
(CHEMBL5559362)
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Affinity Data
IC50: 2.00E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
Copy Entry DOI
PubMed
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Target
DNA repair protein RAD52 homolog
(Human)
University of Bologna
Curated by
ChEMBL
Ligand
BDBM50635710
(CHEMBL5542154)
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Affinity Data
IC50: 2.00E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
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PubMed
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Target
DNA polymerase theta
(Human)
University of Bologna
Curated by
ChEMBL
Ligand
BDBM50226181
(Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-...)
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Affinity Data
IC50: 2.40E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
PC cid
PC sid
Similars
In Depth
Date in BDB:
10/11/2025
Entry Details
Copy Entry DOI
PubMed
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Target
DNA repair protein RAD51 homolog 1
(Human)
University of Bologna
Curated by
ChEMBL
Ligand
BDBM50635709
(CHEMBL5527941)
Copy SMILES
Copy InChI
Affinity Data
Ki: 366nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PDB
In Depth
Date in BDB:
10/11/2025
Entry Details
Copy Entry DOI
PubMed
Copy Rxn URL