BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.1M data for 1.3M Compounds and 9.6K Targets. Of those, 1.5M data for 698K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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To help with training and testing AI and other models, BindingDB downloads and search results now provide the publication date and BindingDB curation date of each measurement.

12 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Discovery of 2-(6-(5-Chloro-2-methoxyphenyl)-4-oxo-2-thioxo-3,4-dihydropyrimidin-1(2H)-yl)acetamide (PF-06282999): A Highly Selective Mechanism-Based Myeloperoxidase Inhibitor for the Treatment of Cardiovascular Diseases.EBI
Pfizer
Discovery of AZD4831, a Mechanism-Based Irreversible Inhibitor of Myeloperoxidase, As a Potential Treatment for Heart Failure with Preserved Ejection Fraction.EBI
Astrazeneca
Small molecule and macrocyclic pyrazole derived inhibitors of myeloperoxidase (MPO).EBI
Bristol-Myers Squibb
Discovery and structure activity relationships of 7-benzyl triazolopyridines as stable, selective, and reversible inhibitors of myeloperoxidase.EBI
Bristol Myers Squibb
Discovery of a novel indole pharmacophore for the irreversible inhibition of myeloperoxidase (MPO).EBI
Novartis Institutes For Biomedical Research
Potent Triazolopyridine Myeloperoxidase Inhibitors.EBI
Bristol-Myers Squibb Research and Development
INHIBITING SEROTONIN TRANSPORTER PROTEIN (5-HTT)BDB
Sensorium Therapeutics
Pyrrolidine Main Protease Inhibitors as Antiviral AgentsBDB
Abbvie
Substituted n′-hydroxycarbamimidoyl-1,2,5-oxadiazole compounds as indoleamine 2,3-dioxygenase (IDO) inhibitorsBDB
Merck Sharp & Dohme
Amino-substituted imidazopyridazinesBDB
Bayer Intellectual Property
Carbamate/urea derivatives containing piperidin and piperazin rings as H3 receptor inhibitorsBDB
Novartis
7-membered ring compound and method of production and pharmaceutical application thereofBDB
Daiichi Sankyo