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BindingDB contains 3.1M data for 1.3M Compounds and 9.6K Targets. Of those, 1.5M data for 698K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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20 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
2-Amino-3-(phenylsulfanyl)norbornane-2-carboxylate: an appealing scaffold for the design of Rac1-Tiam1 protein-protein interaction inhibitors.EBI
University of Milan
Structure-activity relationship of isoform selective inhibitors of Rac1/1b GTPase nucleotide binding.EBI
Exonhit Therapeutics
Virtual screening approach for the identification of new Rac1 inhibitors.EBI
University of Milan
Advances in the development of Rho GTPase inhibitors.EBI
Shanghai Jiao Tong University
Targeting Small GTPases and Their Prenylation in Diabetes Mellitus.EBI
Lodz University of Technology
Design, synthesis and biological evaluation of new carbazole derivatives as anti-cancer and anti-migratory agents.EBI
University of Puerto Rico
Indazoles and use thereofBDB
Purdue Pharma
Benzylamine derivativesBDB
Kalvista Pharmceuticals
Piperidinone carboxamide azaindane CGRP receptor antagonistsBDB
Merck Sharp & Dohme
Pyridinecarboxamides as CXCR2 modulatorsBDB
Syntrix Biosystems
Pyridine compoundsBDB
Daiichi Sankyo
3,3-difluoro-piperidine derivatives as NR2B NMDA receptor antagonistsBDB
Rugen Holdings (Cayman)
Substituted pyrrolo[3,4-e]indolizines, imidazo[1,2-a]pyrrolo[3,4-e]pyridines, pyrrolo[3,4-e][1,2,4]triazolo[1,5-a]pyridines and pyrrolo[3,4-e][1,2,4]triazolo[4,3-a]pyridines as positive allosteric modulators of muscarinic acetylcholine receptor M1BDB
Vanderbilt University
Benzothiazole and benzisothiazole-substituted compounds as mGluR4 allosteric potentiators, compositions, and methods of treating neurological dysfunctionBDB
Vanderbilt University
Phosphatidylinositol 3-kinase inhibitorsBDB
Gilead Sciences
Novel aminophenyl benzamide-type histone deacetylase inhibitors with enhanced potency and selectivity.BDB
Methylgene
2,4-diaminopyrimidine derivatives as potent growth hormone secretagogue receptor antagonists.BDB
Abbott Laboratories
Discovery and pharmacological evaluation of growth hormone secretagogue receptor antagonists.BDB
Abbott Laboratories
Synthesis and monoamine oxidase inhibitory activity of new pyridazine-, pyrimidine- and 1,2,4-triazine-containing tricyclic derivatives.BDB
University of Bari
Tumor suppression by a rationally designed reversible inhibitor of methionine aminopeptidase-2.BDB
Abbott Laboratories