15 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
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Article Title
Organization
Fragment-Based Discovery of 2-Aminoquinazolin-4(3H)-ones As Novel Class Nonpeptidomimetic Inhibitors of the Plasmepsins I, II, and IV.
Latvian Institute of Organic Synthesis
Plasmepsin inhibitory activity and structure-guided optimization of a potent hydroxyethylamine-based antimalarial hit.
Latvian Institute of Organic Synthesis
alpha-Substituted norstatines as the transition-state mimic in inhibitors of multiple digestive vacuole malaria aspartic proteases.
Uppsala University
Expedient solid-phase synthesis of both symmetric and asymmetric diol libraries targeting aspartic proteases.
National University of Singapore
High antiplasmodial activity of novel plasmepsins I and II inhibitors.
University of Milan
Synthesis of malarial plasmepsin inhibitors and prediction of binding modes by molecular dynamics simulations.
Uppsala University
Design and synthesis of potent inhibitors of plasmepsin I and II: X-ray crystal structure of inhibitor in complex with plasmepsin II.
LinköPing University
Plasmepsin Inhibitors in Antimalarial Drug Discovery: Medicinal Chemistry and Target Validation (2000 to Present).
University of Zambia
Peptidomimetic plasmepsin inhibitors with potent anti-malarial activity and selectivity against cathepsin D.
Latvian Institute of Organic Synthesis
2-Aminoquinazolin-4(3H)-one based plasmepsin inhibitors with improved hydrophilicity and selectivity.
Latvian Institute of Organic Synthesis
Cyclic HIV-1 protease inhibitors derived from mannitol: synthesis, inhibitory potencies, and computational predictions of binding affinities.
Uppsala University