Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 366
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Uppsala University

LigandPNGBDBM1158((4S,5R,6R,7S)-1,3-dibenzyl-5,6-dihydroxy-4,7-bis(p...)
Affinity DatapH: 5.5 T: 2°CAssay Description:The IC50 value is the inhibitor concentration that results in 50% of HIV-1 protease activity measured by a spectrophotometric assay using a chromopho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Uppsala University

LigandPNGBDBM1159((4S,5S,6S,7S)-1,3-Dibenzyl-4,7-bis(phenoxymethyl)-...)
Affinity DatapH: 5.5 T: 2°CAssay Description:The IC50 value is the inhibitor concentration that results in 50% of HIV-1 protease activity measured by a spectrophotometric assay using a chromopho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Uppsala University

LigandPNGBDBM1160((4R,5R,6R,7R)-1,3-dibenzyl-5,6-dihydroxy-4,7-bis(p...)
Affinity DatapH: 5.5 T: 2°CAssay Description:The IC50 value is the inhibitor concentration that results in 50% of HIV-1 protease activity measured by a spectrophotometric assay using a chromopho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Uppsala University

LigandPNGBDBM1165((4R,5S,6S,7R)-1,3-Bis{[4-(methoxycarbonyl)phenyl]m...)
Affinity DataIC50: 8.00E+3nMpH: 5.5 T: 2°CAssay Description:The IC50 value is the inhibitor concentration that results in 50% of HIV-1 protease activity measured by a spectrophotometric assay using a chromopho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Uppsala University

LigandPNGBDBM1166((4R,5S,6S,7R)-5,6-dihydroxy-1,3-bis({[4-(hydroxyme...)
Affinity DataKi: <1nM ΔG°: <-53.4kJ/mole IC50: 10nMpH: 5.5 T: 2°CAssay Description:The IC50 value is the inhibitor concentration that results in 50% of HIV-1 protease activity measured by a spectrophotometric assay using a chromopho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Uppsala University

LigandPNGBDBM150((4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-1,3-bis({...)
Affinity DataKi: <1nM ΔG°: <-53.4kJ/mole IC50: 15nMpH: 5.5 T: 2°CAssay Description:The IC50 value is the inhibitor concentration that results in 50% of HIV-1 protease activity measured by a spectrophotometric assay using a chromopho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Uppsala University

LigandPNGBDBM1157((4R,5S,6S,7R)-1,3-dibenzyl-5,6-dihydroxy-4,7-bis(p...)
Affinity DataKi:  12.2nM ΔG°:  -47.0kJ/mole IC50: 80nMpH: 5.5 T: 2°CAssay Description:The IC50 value is the inhibitor concentration that results in 50% of HIV-1 protease activity measured by a spectrophotometric assay using a chromopho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Uppsala University

LigandPNGBDBM1164((3R,4S,5S,6R)-2,7-dibenzyl-4,5-dihydroxy-3,6-bis(2...)
Affinity DataKi:  14.7nM ΔG°:  -46.5kJ/mole IC50: 200nMpH: 5.5 T: 2°CAssay Description:The IC50 value is the inhibitor concentration that results in 50% of HIV-1 protease activity measured by a spectrophotometric assay using a chromopho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Uppsala University

LigandPNGBDBM1163(CHEMBL130998 | Cyclic Sulfamide deriv. 19 | (3R,4S...)
Affinity DataKi:  19.1nM ΔG°:  -45.8kJ/mole IC50: 200nMpH: 5.5 T: 2°CAssay Description:The IC50 value is the inhibitor concentration that results in 50% of HIV-1 protease activity measured by a spectrophotometric assay using a chromopho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Uppsala University

LigandPNGBDBM1161((4R,5S,6S,7R)-1,3-Dibenzyl-4,7-bis(2-phenylethyl)-...)
Affinity DataKi:  214nM ΔG°:  -39.6kJ/mole IC50: 4.00E+3nMpH: 5.5 T: 2°CAssay Description:The IC50 value is the inhibitor concentration that results in 50% of HIV-1 protease activity measured by a spectrophotometric assay using a chromopho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Uppsala University

LigandPNGBDBM1162((4R,5S,6S,7R)-1,3-Dibenzyl-4,7-bis(3-phenylpropyl)...)
Affinity DataKi:  570nM ΔG°:  -37.1kJ/mole IC50: 1.00E+4nMpH: 5.5 T: 2°CAssay Description:The IC50 value is the inhibitor concentration that results in 50% of HIV-1 protease activity measured by a spectrophotometric assay using a chromopho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2004
Entry Details Article
PubMed