BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.1M data for 1.3M Compounds and 9.6K Targets. Of those, 1.5M data for 698K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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To help with training and testing AI and other models, BindingDB downloads and search results now provide the publication date and BindingDB curation date of each measurement.

5 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Discovery of Novel Potent Covalent Glutathione Peroxidase 4 Inhibitors as Highly Selective Ferroptosis Inducers for the Treatment of Triple-Negative Breast Cancer.EBI
China Pharmaceutical University
Dual degradation mechanism of GPX4 degrader in induction of ferroptosis exerting anti-resistant tumor effect.EBI
Peking University
Discovery of ML210-Based glutathione peroxidase 4 (GPX4) degrader inducing ferroptosis of human cancer cells.EBI
Peking University
Structure-activity relationships of GPX4 inhibitor warheads.EBI
Institute of Mit and Harvard
Allosteric Modulator Discovery: From Serendipity to Structure-Based Design.EBI
Shanghai Jiao-Tong University School of Medicine