Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 50009378
TargetNAD-dependent protein deacylase sirtuin-6(Human)
Shanghai Jiao-Tong University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50528214(CHEMBL4592529)
Affinity DataEC50:  2.18E+5nMAssay Description:Inhibition of SIRT6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Shanghai Jiao-Tong University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50528215(CHEMBL4562495)
Affinity DataKd:  3.22E+3nMAssay Description:Binding affinity to STAT3 CCD (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-6(Human)
Shanghai Jiao-Tong University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50528216(CHEMBL4440358)
Affinity DataEC50:  5.70E+3nMAssay Description:Inhibition of SIRT6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNAD-dependent protein deacylase sirtuin-6(Human)
Shanghai Jiao-Tong University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50528217(CHEMBL4538188)
Affinity DataEC50:  1.74E+5nMAssay Description:Inhibition of SIRT6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-6(Human)
Shanghai Jiao-Tong University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50528218(CHEMBL4551664)
Affinity DataEC50:  1.03E+4nMAssay Description:Inhibition of SIRT6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
Shanghai Jiao-Tong University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50528219(CHEMBL1230164)
Affinity DataKd:  6.30E+4nMAssay Description:Binding affinity to GPX4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Shanghai Jiao-Tong University School of Medicine

Curated by ChEMBL
LigandPNGBDBM60927(ANS | BDBM50126831 | 1-anilinonaphthalene-8-sulfon...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of p38alpha (unknown origin) using biotinylated maltose peptide as substrate after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 12(Human)
Shanghai Jiao-Tong University School of Medicine

Curated by ChEMBL
LigandPNGBDBM60927(ANS | BDBM50126831 | 1-anilinonaphthalene-8-sulfon...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of p38gamma (unknown origin) using biotinylated maltose peptide as substrate after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 13(Human)
Shanghai Jiao-Tong University School of Medicine

Curated by ChEMBL
LigandPNGBDBM60927(ANS | BDBM50126831 | 1-anilinonaphthalene-8-sulfon...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of p38delta (unknown origin) using biotinylated maltose peptide as substrate after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11(Human)
Shanghai Jiao-Tong University School of Medicine

Curated by ChEMBL
LigandPNGBDBM60927(ANS | BDBM50126831 | 1-anilinonaphthalene-8-sulfon...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of p38beta (unknown origin) using biotinylated maltose peptide as substrate after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetCathepsin K(Human)
Shanghai Jiao-Tong University School of Medicine

Curated by ChEMBL
LigandPNGBDBM52006(2-[[2-(carbamoylthio)-1-oxoethyl]amino]benzoic aci...)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of cathepsin K (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)