34 articles for thisTarget
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Article Title
Organization
Discovery of Novel Potent Reversible and Irreversible Myeloperoxidase Inhibitors Using Virtual Screening Procedure.
Free University of Brussels
Substituted 4,6-diaminoquinolines as inhibitors of C5a receptor binding.
Merck Sharp and Dohme Research Laboratories
Novel bis-arylalkylamines as myeloperoxidase inhibitors: Design, synthesis, and structure-activity relationship study.
Free University of Brussels
Discovery of 2-(6-(5-Chloro-2-methoxyphenyl)-4-oxo-2-thioxo-3,4-dihydropyrimidin-1(2H)-yl)acetamide (PF-06282999): A Highly Selective Mechanism-Based Myeloperoxidase Inhibitor for the Treatment of Cardiovascular Diseases.
Pfizer
Inhibition of myeloperoxidase: evaluation of 2H-indazoles and 1H-indazolones.
University of California
Biologically active eremophilane-type sesquiterpenes from Camarops sp., an endophytic fungus isolated from Alibertia macrophylla.
Universidade Estadual Paulista
Design, synthesis, and structure-activity relationship studies of novel 3-alkylindole derivatives as selective and highly potent myeloperoxidase inhibitors.
Free University of Brussels
Evaluation of new scaffolds of myeloperoxidase inhibitors by rational design combined with high-throughput virtual screening.
Free University of Brussels
Conception of myeloperoxidase inhibitors derived from flufenamic acid by computational docking and structure modification.
Free University of Brussels
Structure-based design, synthesis, and pharmacological evaluation of 3-(aminoalkyl)-5-fluoroindoles as myeloperoxidase inhibitors.
Universite£? Libre De Bruxelles
Design, synthesis, and biological activity studies on benzimidazole derivatives targeting myeloperoxidase.
Izmir Katip Celebi University
Discovery of AZD4831, a Mechanism-Based Irreversible Inhibitor of Myeloperoxidase, As a Potential Treatment for Heart Failure with Preserved Ejection Fraction.
Astrazeneca
Small molecule and macrocyclic pyrazole derived inhibitors of myeloperoxidase (MPO).
Bristol-Myers Squibb
Discovery and structure activity relationships of 7-benzyl triazolopyridines as stable, selective, and reversible inhibitors of myeloperoxidase.
Bristol Myers Squibb
Discovery of a novel indole pharmacophore for the irreversible inhibition of myeloperoxidase (MPO).
Novartis Institutes For Biomedical Research
Potent Triazolopyridine Myeloperoxidase Inhibitors.
Bristol-Myers Squibb Research and Development
The development of myeloperoxidase inhibitors.
University Sarajevo School of Science and Technology
Thioxo-dihydroquinazolin-one Compounds as Novel Inhibitors of Myeloperoxidase.
Emory University
Improvements in the minimum binding sequence of C5a: examination of His-67.
Abbott Laboratories
Novel benzothiophene-, benzofuran-, and naphthalenecarboxamidotetrazoles as potential antiallergy agents.
Warner-Lambert
Cyanopyrrolidine derivatives with activity as inhibitors of USP30
Mission Therapeutics
Substituted n′-hydroxycarbamimidoyl-1,2,5-oxadiazole compounds as indoleamine 2,3-dioxygenase (IDO) inhibitors
Merck Sharp & Dohme
HYPDH inhibitors and methods of use for the treatment of kidney stones
Wake Forest University Health Sciences
(Hetero)aryl imidazoles/pyrazoles for treatment of neurological disorders
Hoffmann-La Roche
Coregulator control of androgen receptor action by a novel nuclear receptor-binding motif.
Karlsruhe Institute of Technology
Carbamate/urea derivatives containing piperidin and piperazin rings as H3 receptor inhibitors
Novartis
7-membered ring compound and method of production and pharmaceutical application thereof
Daiichi Sankyo