The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.5M data for 728K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

If BindingDB was of value to your research, please take a moment to donate to this nonprofit project. Your donation will let us provide you with more data and improved service.

To help with training and testing AI and other models, BindingDB downloads and search results now provide the publication date and BindingDB curation date of each measurement.

13 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Design, synthesis and biological activity of original pyrazolo-pyrido-diazepine, -pyrazine and -oxazine dione derivatives as novel dual Nox4/Nox1 inhibitors.EBI
Genkyotex
First in class, potent, and orally bioavailable NADPH oxidase isoform 4 (Nox4) inhibitors for the treatment of idiopathic pulmonary fibrosis.EBI
Genkyotex
Targeting NOX2 with Bivalent Small-Molecule p47phox-p22phox Inhibitors.EBI
University of Copenhagen
NADPH Oxidases: From Molecular Mechanisms to Current Inhibitors.EBI
TBA
Discovery of a NADPH oxidase inhibitor, (E)-3-cyclohexyl-5-(4-((2-hydroxyethyl)(methyl)amino)benzylidene)-1-methyl-2-thioxoimidazolidin-4-oneone, as a novel therapeutic for Parkinson's disease.EBI
Korea University
A closer look at NEBI
Monash University Malaysia
Bridged tetrahydroisoquinolines as selective NADPH oxidase 2 (Nox2) inhibitors.EBI
University of Pittsburgh
The medicinal chemistry of mitochondrial dysfunction: a critical overview of efforts to modulate mitochondrial health.EBI
Msd The Francis Crick Institute
Ethynyl derivativesBDB
Hoffmann-La Roche
BICYCLIC HETEROCYCLIC FGFR4 INHIBITOR, PHARMACEUTICAL COMPOSITION AND PREPARATION COMPRISING SAME, AND APPLICATION THEREOFBDB
Hangzhou Apeloa Medicine Research Institute Co.
Liver X receptor (LXR) modulatorsBDB
Ralexar Therapeutics
Inhibitors of protein tyrosine phosphatasesBDB
Indiana University Research and Technology
Derivatives of N-acyl-N′-phenylpiperazine useful (inter alia) for the prophylaxis or treatment of diabetesBDB
Takeda Pharmaceutical