38 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
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Article Title
Organization
Dipeptidyl Nitroalkenes as Potent Reversible Inhibitors of Cysteine Proteases Rhodesain and Cruzain.
Universitat Jaume I
Development of novel 1,4-benzodiazepine-based Michael acceptors as antitrypanosomal agents.
University of Messina
Development of novel dipeptide-like rhodesain inhibitors containing the 3-bromoisoxazoline warhead in a constrained conformation.
University of Messina
Constrained peptidomimetics as antiplasmodial falcipain-2 inhibitors.
University of Messina
Novel 2H-isoquinolin-3-ones as antiplasmodial falcipain-2 inhibitors.
University of Messina
Dipeptidyl-alpha,beta-epoxyesters as potent irreversible inhibitors of the cysteine proteases cruzain and rhodesain.
Universitat Jaume I
Identification of novel parasitic cysteine protease inhibitors using virtual screening. 1. The ChemBridge database.
University of Mississippi
Identification of novel parasitic cysteine protease inhibitors by use of virtual screening. 2. The available chemical directory.
University of Mississippi
Allicin and derivates are cysteine protease inhibitors with antiparasitic activity.
University of WüRzburg
Synthesis of novel peptidomimetics as inhibitors of protozoan cysteine proteases falcipain-2 and rhodesain.
University of Messina
On-bead screening of a combinatorial fumaric acid derived peptide library yields antiplasmodial cysteine protease inhibitors with unusual peptide sequences.
University of Duisburg-Essen
Michael acceptor based antiplasmodial and antitrypanosomal cysteine protease inhibitors with unusual amino acids.
University of W£Rzburg
Novel non-peptidic vinylsulfones targeting the S2 and S3 subsites of parasite cysteine proteases.
University of California
Synthesis and structure-activity relationship studies of cruzain and rhodesain inhibitors.
Universidade Federal Do Rio Grande Do Sul
Development of novel dipeptide nitriles as inhibitors of rhodesain of Trypanosoma brucei rhodesiense.
University of Messina
Aziridine-2,3-dicarboxylate inhibitors targeting the major cysteine protease of Trypanosoma brucei as lead trypanocidal agents.
University of Wuerzburg
Development of Urea-Bond-Containing Michael Acceptors as Antitrypanosomal Agents Targeting Rhodesain.
University of Messina
New peptidomimetic rhodesain inhibitors with improved selectivity towards human cathepsins.
Johannes Gutenberg University
Discovery of potent thiosemicarbazone inhibitors of rhodesain and cruzain.
University of California San Francisco
Synthesis and structure-activity relationships of parasiticidal thiosemicarbazone cysteine protease inhibitors against Plasmodium falciparum, Trypanosoma brucei, and Trypanosoma cruzi.
University of California San Francisco
Structure-Based Optimization of Quinazolines as Cruzain and
Federal University of Minas Gerais (Ufmg)
Fluorovinylsulfones and -Sulfonates as Potent Covalent Reversible Inhibitors of the Trypanosomal Cysteine Protease Rhodesain: Structure-Activity Relationship, Inhibition Mechanism, Metabolism, and In Vivo Studies.
Johannes Gutenberg University
Computer-aided design of 1,4-naphthoquinone-based inhibitors targeting cruzain and rhodesain cysteine proteases.
Federal University of Alagoas
Synthesis and biological screening of thiosemicarbazones of substituted 3-acetylcoumarins having d-glucose moiety.
Institute For Advanced Technology (Vietnam Academy of Military Science and Technology)
Discovery and characterization of trypanocidal cysteine protease inhibitors from the 'malaria box'.
Universidade Federal De Minas Gerais
Drug Synergism: Studies of Combination of RK-52 and Curcumin against Rhodesain of
University of Messina
Nostotrebin 6 Related Cyclopentenediones and δ-Lactones with Broad Activity Spectrum Isolated from the Cultivation Medium of the Cyanobacterium
University of Halle-Wittenberg
Optimization Strategy of Novel Peptide-Based Michael Acceptors for the Treatment of Human African Trypanosomiasis.
University of Messina
Can Cysteine Protease Cross-Class Inhibitors Achieve Selectivity?
University of S£O Paulo
New aziridine-based inhibitors of cathepsin L-like cysteine proteases with selectivity for the Leishmania cysteine protease LmCPB2.8.
Johannes Gutenberg-Universit£T Mainz
Antiprotozoal and cysteine proteases inhibitory activity of dipeptidyl enoates.
Universitat Jaume I
Discovery of a quinoline-based phenyl sulfone derivative as an antitrypanosomal agent.
Jackson State University
Bistacrines as potential antitrypanosomal agents.
Julius-Maximilians-University of W£Rzburg
2 H-1,2,3-Triazole-Based Dipeptidyl Nitriles: Potent, Selective, and Trypanocidal Rhodesain Inhibitors by Structure-Based Design.
Eth Zurich
Repurposing a Library of Human Cathepsin L Ligands: Identification of Macrocyclic Lactams as Potent Rhodesain and Trypanosoma brucei Inhibitors.
Eth Zurich