Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 50014828
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50114651((1E)-1-(3-bromophenyl)ethan-1-one thiosemicarbazon...)
Affinity DataIC50: 50nMAssay Description:Inhibition of rhodesain from Trypanosoma brucei rhodesienseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCruzipain(Trypanosoma cruzi)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50114651((1E)-1-(3-bromophenyl)ethan-1-one thiosemicarbazon...)
Affinity DataIC50: 60nMAssay Description:Inhibition of cruzain from Trypanosoma cruziMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50148049((1E)-1-(1,1'-biphenyl-4-yl)ethan-1-one thiosemicar...)
Affinity DataIC50: 90nMAssay Description:Inhibition of rhodesain from Trypanosoma brucei rhodesienseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50148061((1Z)-1-{3-[(1E)-N-(aminocarbonothioyl)ethanehydraz...)
Affinity DataIC50: 330nMAssay Description:Inhibition of rhodesain from Trypanosoma brucei rhodesienseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50148055((1E)-1-(3-phenoxyphenyl)ethan-1-one thiosemicarbaz...)
Affinity DataIC50: 550nMAssay Description:Inhibition of rhodesain from Trypanosoma brucei rhodesienseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50148057((1E)-1-(3-anilinophenyl)ethan-1-one thiosemicarbaz...)
Affinity DataIC50: 800nMAssay Description:Inhibition of rhodesain from Trypanosoma brucei rhodesienseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50148053((1E)-1-(1,1'-biphenyl-3-yl)ethan-1-one thiosemicar...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of rhodesain from Trypanosoma brucei rhodesienseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50148060((1E)-1-(3-bromophenyl)ethan-1-one N,N-diethylthios...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of rhodesain from Trypanosoma brucei rhodesienseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50148052(N'-[(1E)-1-(3-bromophenyl)ethylidene]piperidine-1-...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of rhodesain from Trypanosoma brucei rhodesienseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50148058(N'-[(1E)-1-(3-bromophenyl)ethylidene]-4-methylpipe...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of rhodesain from Trypanosoma brucei rhodesienseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCruzipain(Trypanosoma cruzi)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50148058(N'-[(1E)-1-(3-bromophenyl)ethylidene]-4-methylpipe...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of cruzain from Trypanosoma cruziMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCruzipain(Trypanosoma cruzi)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50148061((1Z)-1-{3-[(1E)-N-(aminocarbonothioyl)ethanehydraz...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of cruzain from Trypanosoma cruziMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCruzipain(Trypanosoma cruzi)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50148060((1E)-1-(3-bromophenyl)ethan-1-one N,N-diethylthios...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of cruzain from Trypanosoma cruziMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCruzipain(Trypanosoma cruzi)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50148049((1E)-1-(1,1'-biphenyl-4-yl)ethan-1-one thiosemicar...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of cruzain from Trypanosoma cruziMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCruzipain(Trypanosoma cruzi)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50148052(N'-[(1E)-1-(3-bromophenyl)ethylidene]piperidine-1-...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of cruzain from Trypanosoma cruziMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50148050((1E)-1-(4-phenoxyphenyl)ethan-1-one thiosemicarbaz...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of rhodesain from Trypanosoma brucei rhodesienseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCruzipain(Trypanosoma cruzi)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50148053((1E)-1-(1,1'-biphenyl-3-yl)ethan-1-one thiosemicar...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of cruzain from Trypanosoma cruziMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCruzipain(Trypanosoma cruzi)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50148055((1E)-1-(3-phenoxyphenyl)ethan-1-one thiosemicarbaz...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of cruzain from Trypanosoma cruziMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCruzipain(Trypanosoma cruzi)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50148050((1E)-1-(4-phenoxyphenyl)ethan-1-one thiosemicarbaz...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of cruzain from Trypanosoma cruziMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFalcipain 2(malaria parasite P. falciparum)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50148049((1E)-1-(1,1'-biphenyl-4-yl)ethan-1-one thiosemicar...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of falcipain2 from Plasmodium falciparumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50148059((1E)-1-(4-anilinophenyl)ethan-1-one thiosemicarbaz...)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of rhodesain from Trypanosoma brucei rhodesienseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCruzipain(Trypanosoma cruzi)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50148062((2E)-2-[1-(3-bromophenyl)ethylidene]hydrazinecarbo...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of cruzain from Trypanosoma cruziMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCruzipain(Trypanosoma cruzi)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50148059((1E)-1-(4-anilinophenyl)ethan-1-one thiosemicarbaz...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of cruzain from Trypanosoma cruziMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50148062((2E)-2-[1-(3-bromophenyl)ethylidene]hydrazinecarbo...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of rhodesain from Trypanosoma brucei rhodesienseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCruzipain(Trypanosoma cruzi)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50148057((1E)-1-(3-anilinophenyl)ethan-1-one thiosemicarbaz...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of cruzain from Trypanosoma cruziMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFalcipain 2(malaria parasite P. falciparum)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50148058(N'-[(1E)-1-(3-bromophenyl)ethylidene]-4-methylpipe...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of falcipain2 from Plasmodium falciparumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCruzipain(Trypanosoma cruzi)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50148056(2-acetylpyridine thiosemicarbazone | (1E)-1-pyridi...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of cruzain from Trypanosoma cruziMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50148056(2-acetylpyridine thiosemicarbazone | (1E)-1-pyridi...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of rhodesain from Trypanosoma brucei rhodesienseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50148051(N'-[1-Pyridin-2-yl-eth-(E)-ylidene]-hydrazinecarbo...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of rhodesain from Trypanosoma brucei rhodesienseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFalcipain 2(malaria parasite P. falciparum)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50148054((1Z)-1-{6-[(1E)-N-(aminocarbonothioyl)ethanehydraz...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of falcipain2 from Plasmodium falciparumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFalcipain 2(malaria parasite P. falciparum)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50148056(2-acetylpyridine thiosemicarbazone | (1E)-1-pyridi...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of falcipain2 from Plasmodium falciparumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFalcipain 2(malaria parasite P. falciparum)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50148051(N'-[1-Pyridin-2-yl-eth-(E)-ylidene]-hydrazinecarbo...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of falcipain2 from Plasmodium falciparumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFalcipain 2(malaria parasite P. falciparum)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50148059((1E)-1-(4-anilinophenyl)ethan-1-one thiosemicarbaz...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of falcipain2 from Plasmodium falciparumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed