25 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
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Article Title
Organization
"Cyclopenta[c]pyrrol Negative Allosteric Modulators of NR2B"

Novartis
MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF

Children'S Hospital Medical Center
Combination therapies using immuno-dash inhibitors and PGE2 antagonists

Tufts College
Heterocyclic compounds as PI3K-γ inhibitors

Incyte
Chiral N-acyl-5,6,7,(8-substituted)-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazines as selective NK-3 receptor antagonists, pharmaceutical composition, methods for use in NK-3 receptor mediated disorders and chiral synthesis thereof

Ogeda
Arylcyclopropylamine based demethylase inhibitors of LSD1 and their medical use

Oryzon Genomics
Flouro-naphthyl derivatives

Hoffmann-La Roche
Substituted 2-aminopyridine protein kinase inhibitor

Chia Tai Tianqing Pharmaceutical Group
2-acylaminothiazoles for the treatment of cancer

UniversitÁ
Heterocyclic compounds and methods for their use

Novartis
Inhibitors of protein kinase C. 2. Substituted bisindolylmaleimides with improved potency and selectivity.

Roche Products
Benzocycloalkyl amines as novel C-termini for HIV protease inhibitors.

Merck Sharp and Dohme Research Laboratories
Potent, orally bioavailable HIV-1 protease inhibitors containing noncoded D-amino acids

Eli Lilly
A major role for a set of non-active site mutations in the development of HIV-1 protease drug resistance.

Johns Hopkins University
An ethylenamine inhibitor binds tightly to both wild type and mutant HIV-1 proteases. Structure and energy study.

Academy of Sciences of The Czech Republic
Beta-strand mimicking macrocyclic amino acids: templates for protease inhibitors with antiviral activity.

University of Queensland
In vitro anti-human immunodeficiency virus (HIV) activities of transition state mimetic HIV protease inhibitors containing allophenylnorstatine.

National Cancer Institute-Bethesda
Use of medium-sized cycloalkyl rings to enhance secondary binding: discovery of a new class of human immunodeficiency virus (HIV) protease inhibitors.

Upjohn
Structure-based design of sulfonamide-substituted non-peptidic HIV protease inhibitors.

Upjohn
L-735,524: an orally bioavailable human immunodeficiency virus type 1 protease inhibitor.

Merck Research Laboratories
L-687,908, a potent hydroxyethylene-containing HIV protease inhibitor.

Merck Research Laboratories
Design and fast synthesis of C-terminal duplicated potent C(2)-symmetric P1/P1'-modified HIV-1 protease inhibitors.

Uppsala University
Amplification of the effects of drug resistance mutations by background polymorphisms in HIV-1 protease from African subtypes.

The Johns Hopkins University
Understanding binding affinity: a combined isothermal titration calorimetry/molecular dynamics study of the binding of a series of hydrophobically modified benzamidinium chloride inhibitors to trypsin.

University of Groningen