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BindingDB contains 3.1M data for 1.3M Compounds and 9.6K Targets. Of those, 1.5M data for 698K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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25 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
"Cyclopenta[c]pyrrol Negative Allosteric Modulators of NR2B"BDB
Novartis
MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOFBDB
Children'S Hospital Medical Center
Combination therapies using immuno-dash inhibitors and PGE2 antagonistsBDB
Tufts College
Heterocyclic compounds as PI3K-γ inhibitorsBDB
Incyte
Chiral N-acyl-5,6,7,(8-substituted)-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazines as selective NK-3 receptor antagonists, pharmaceutical composition, methods for use in NK-3 receptor mediated disorders and chiral synthesis thereofBDB
Ogeda
Arylcyclopropylamine based demethylase inhibitors of LSD1 and their medical useBDB
Oryzon Genomics
Flouro-naphthyl derivativesBDB
Hoffmann-La Roche
Substituted 2-aminopyridine protein kinase inhibitorBDB
Chia Tai Tianqing Pharmaceutical Group
2-acylaminothiazoles for the treatment of cancerBDB
UniversitÁ
Heterocyclic compounds and methods for their useBDB
Novartis
Inhibitors of protein kinase C. 2. Substituted bisindolylmaleimides with improved potency and selectivity.BDB
Roche Products
Benzocycloalkyl amines as novel C-termini for HIV protease inhibitors.BDB
Merck Sharp and Dohme Research Laboratories
 
Potent, orally bioavailable HIV-1 protease inhibitors containing noncoded D-amino acidsBDB
Eli Lilly
A major role for a set of non-active site mutations in the development of HIV-1 protease drug resistance.BDB
Johns Hopkins University
An ethylenamine inhibitor binds tightly to both wild type and mutant HIV-1 proteases. Structure and energy study.BDB
Academy of Sciences of The Czech Republic
Beta-strand mimicking macrocyclic amino acids: templates for protease inhibitors with antiviral activity.BDB
University of Queensland
In vitro anti-human immunodeficiency virus (HIV) activities of transition state mimetic HIV protease inhibitors containing allophenylnorstatine.BDB
National Cancer Institute-Bethesda
Use of medium-sized cycloalkyl rings to enhance secondary binding: discovery of a new class of human immunodeficiency virus (HIV) protease inhibitors.BDB
Upjohn
Structure-based design of sulfonamide-substituted non-peptidic HIV protease inhibitors.BDB
Upjohn
L-735,524: an orally bioavailable human immunodeficiency virus type 1 protease inhibitor.BDB
Merck Research Laboratories
L-687,908, a potent hydroxyethylene-containing HIV protease inhibitor.BDB
Merck Research Laboratories
Design and fast synthesis of C-terminal duplicated potent C(2)-symmetric P1/P1'-modified HIV-1 protease inhibitors.BDB
Uppsala University
Amplification of the effects of drug resistance mutations by background polymorphisms in HIV-1 protease from African subtypes.BDB
The Johns Hopkins University
Understanding binding affinity: a combined isothermal titration calorimetry/molecular dynamics study of the binding of a series of hydrophobically modified benzamidinium chloride inhibitors to trypsin.BDB
University of Groningen