Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 500
TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM3175(Bisindolylmaleimide 11b | Ro 31-8220 | CHEMBL6291 ...)
Affinity DataIC50: 10nMAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2005
Entry Details Article
PubMed
TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM3179(3-(3-{3-[4-(1-methyl-1H-indol-3-yl)-2,5-dioxo-2,5-...)
Affinity DataIC50: 19nMAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2005
Entry Details Article
PubMed
TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM3178(3-(1-Methyl-3-indolyl)-4-[1-[3-(2-nitroguanidino)p...)
Affinity DataIC50: 26nMAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2005
Entry Details Article
PubMed
TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM3176([(4-{3-[4-(1-methyl-1H-indol-3-yl)-2,5-dioxo-2,5-d...)
Affinity DataIC50: 28nMAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2005
Entry Details Article
PubMed
TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM3180(5-{3-[4-(1-methyl-1H-indol-3-yl)-2,5-dioxo-2,5-dih...)
Affinity DataIC50: 31nMAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2005
Entry Details Article
PubMed
TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM3171(3-[1-[3-(Methylamino)propyl]-3-indolyl]-4-(1-methy...)
Affinity DataIC50: 35nMpH: 7.5 T: 2°CAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2005
Entry Details Article
PubMed
TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM3174([(2-{3-[4-(1-methyl-1H-indol-3-yl)-2,5-dioxo-2,5-d...)
Affinity DataIC50: 41nMAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2005
Entry Details Article
PubMed
TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM2681(3-{1-[3-(dimethylamino)propyl]-1H-indol-3-yl}-4-(1...)
Affinity DataIC50: 45nMAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2005
Entry Details Article
PubMed
TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM3177([(5-{3-[4-(1-methyl-1H-indol-3-yl)-2,5-dioxo-2,5-d...)
Affinity DataIC50: 47nMAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2005
Entry Details Article
PubMed
TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM3169(3-[1-(4-aminobutyl)-1H-indol-3-yl]-4-(1-methyl-1H-...)
Affinity DataIC50: 55nMpH: 7.5 T: 2°CAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2005
Entry Details Article
PubMed
TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM3167(3-[1-(2-aminoethyl)-1H-indol-3-yl]-4-(1-methyl-1H-...)
Affinity DataIC50: 64nMpH: 7.5 T: 2°CAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2005
Entry Details Article
PubMed
TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM2695(Ro 31-7549 | 3-[1-(3-aminopropyl)-1H-indol-3-yl]-4...)
Affinity DataIC50: 75nMpH: 7.5 T: 2°CAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2005
Entry Details Article
PubMed
TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM3170(3-[1-(5-aminopentyl)-1H-indol-3-yl]-4-(1-methyl-1H...)
Affinity DataIC50: 76nMpH: 7.5 T: 2°CAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2005
Entry Details Article
PubMed
TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM3173(trimethyl(3-{3-[4-(1-methyl-1H-indol-3-yl)-2,5-dio...)
Affinity DataIC50: 93nMAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2005
Entry Details Article
PubMed
TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM3164(3-[1-(3-Hydroxypropyl)-3-indolyl]-4-(1-methyl-3-in...)
Affinity DataIC50: 130nMpH: 7.5 T: 2°CAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2005
Entry Details Article
PubMed
TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM3165(3-[1-(4-hydroxybutyl)-1H-indol-3-yl]-4-(1-methyl-1...)
Affinity DataIC50: 170nMpH: 7.5 T: 2°CAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2005
Entry Details Article
PubMed
TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM3166(3-[1-(5-hydroxypentyl)-1H-indol-3-yl]-4-(1-methyl-...)
Affinity DataIC50: 280nMpH: 7.5 T: 2°CAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2005
Entry Details Article
PubMed
TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM3163(3-[1-(2-hydroxyethyl)-1H-indol-3-yl]-4-(1-methyl-1...)
Affinity DataIC50: 340nMpH: 7.5 T: 2°CAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2005
Entry Details Article
PubMed
LigandPNGBDBM3175(Bisindolylmaleimide 11b | Ro 31-8220 | CHEMBL6291 ...)
Affinity DataIC50: 900nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2005
Entry Details Article
PubMed
LigandPNGBDBM3176([(4-{3-[4-(1-methyl-1H-indol-3-yl)-2,5-dioxo-2,5-d...)
Affinity DataIC50: 2.70E+3nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2005
Entry Details Article
PubMed
LigandPNGBDBM3179(3-(3-{3-[4-(1-methyl-1H-indol-3-yl)-2,5-dioxo-2,5-...)
Affinity DataIC50: 2.90E+3nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2005
Entry Details Article
PubMed
LigandPNGBDBM3177([(5-{3-[4-(1-methyl-1H-indol-3-yl)-2,5-dioxo-2,5-d...)
Affinity DataIC50: 4.60E+3nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2005
Entry Details Article
PubMed
LigandPNGBDBM3178(3-(1-Methyl-3-indolyl)-4-[1-[3-(2-nitroguanidino)p...)
Affinity DataIC50: 4.90E+3nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2005
Entry Details Article
PubMed
LigandPNGBDBM2695(Ro 31-7549 | 3-[1-(3-aminopropyl)-1H-indol-3-yl]-4...)
Affinity DataIC50: 5.20E+3nMpH: 8.5 T: 2°CAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2005
Entry Details Article
PubMed
LigandPNGBDBM3180(5-{3-[4-(1-methyl-1H-indol-3-yl)-2,5-dioxo-2,5-dih...)
Affinity DataIC50: 7.40E+3nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2005
Entry Details Article
PubMed
LigandPNGBDBM3167(3-[1-(2-aminoethyl)-1H-indol-3-yl]-4-(1-methyl-1H-...)
Affinity DataIC50: 8.90E+3nMpH: 8.5 T: 2°CAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2005
Entry Details Article
PubMed
LigandPNGBDBM3169(3-[1-(4-aminobutyl)-1H-indol-3-yl]-4-(1-methyl-1H-...)
Affinity DataIC50: 9.30E+3nMpH: 8.5 T: 2°CAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2005
Entry Details Article
PubMed
LigandPNGBDBM3170(3-[1-(5-aminopentyl)-1H-indol-3-yl]-4-(1-methyl-1H...)
Affinity DataIC50: 1.04E+4nMpH: 8.5 T: 2°CAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2005
Entry Details Article
PubMed
LigandPNGBDBM3171(3-[1-[3-(Methylamino)propyl]-3-indolyl]-4-(1-methy...)
Affinity DataIC50: 1.19E+4nMpH: 8.5 T: 2°CAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2005
Entry Details Article
PubMed
LigandPNGBDBM3174([(2-{3-[4-(1-methyl-1H-indol-3-yl)-2,5-dioxo-2,5-d...)
Affinity DataIC50: 1.21E+4nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2005
Entry Details Article
PubMed
LigandPNGBDBM3164(3-[1-(3-Hydroxypropyl)-3-indolyl]-4-(1-methyl-3-in...)
Affinity DataIC50: 1.42E+4nMpH: 8.5 T: 2°CAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2005
Entry Details Article
PubMed
LigandPNGBDBM3165(3-[1-(4-hydroxybutyl)-1H-indol-3-yl]-4-(1-methyl-1...)
Affinity DataIC50: 1.84E+4nMpH: 8.5 T: 2°CAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2005
Entry Details Article
PubMed
LigandPNGBDBM3166(3-[1-(5-hydroxypentyl)-1H-indol-3-yl]-4-(1-methyl-...)
Affinity DataIC50: 2.13E+4nMpH: 8.5 T: 2°CAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2005
Entry Details Article
PubMed
LigandPNGBDBM3163(3-[1-(2-hydroxyethyl)-1H-indol-3-yl]-4-(1-methyl-1...)
Affinity DataIC50: 2.21E+4nMpH: 8.5 T: 2°CAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2005
Entry Details Article
PubMed
LigandPNGBDBM2681(3-{1-[3-(dimethylamino)propyl]-1H-indol-3-yl}-4-(1...)
Affinity DataIC50: 2.56E+4nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2005
Entry Details Article
PubMed
LigandPNGBDBM3173(trimethyl(3-{3-[4-(1-methyl-1H-indol-3-yl)-2,5-dio...)
Affinity DataIC50: 6.45E+4nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2005
Entry Details Article
PubMed