BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.1M data for 1.3M Compounds and 9.6K Targets. Of those, 1.5M data for 698K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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To help with training and testing AI and other models, BindingDB downloads and search results now provide the publication date and BindingDB curation date of each measurement.

8 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Optimization of Arylamides as Novel, Potent and Brain-penetrant Antiprion Lead Compounds.EBI
University of California
Antimalarial drug quinacrine binds to C-terminal helix of cellular prion protein.EBI
Institut F£R Molekularbiologie Und Biophysik
Variety of antiprion compounds discovered through an in silico screen based on cellular-form prion protein structure: Correlation between antiprion activity and binding affinity.EBI
Gifu University
Innovative Non-PrP-Targeted Drug Strategy Designed to Enhance Prion Clearance.EBI
Scuola Internazionale Superiore Di Studi Avanzati (Sissa)
The compound (3-{5-[(2,5-dimethoxyphenyl)amino]-1,3,4-thiadiazolidin-2-yl}-5,8-methoxy-2H-chromen-2-one) inhibits the prion protein conversion from PrPEBI
University of Alberta
X-ray Structures of Target-Ligand Complexes Containing Compounds with Assay Interference Potential.EBI
Rheinische Friedrich-Wilhelms-Universit£T
Pyrazolyl substituted carbonic acid derivatives as modulators of the prostacyclin (PGI2) receptor useful for the treatment of disorders related theretoBDB
Arena Pharmaceuticals