18 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
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Article Title
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Development of CoMFA and CoMSIA models of affinity and selectivity for indole ligands of cannabinoid CB1 and CB2 receptors.
Universidade Federal Do Rio De Janeiro
CoMFA and HQSAR of acylhydrazide cruzain inhibitors.
Universidade Federal Do Rio De Janeiro
Design, synthesis, and pharmacological evaluation of N-acylhydrazones and novel conformationally constrained compounds as selective and potent orally active phosphodiesterase-4 inhibitors.
Universidade Federal Do Rio De Janeiro
Discovery of LASSBio-772, a 1,3-benzodioxole N-phenylpiperazine derivative with potent alpha 1A/D-adrenergic receptor blocking properties.
Universidade Federal Do Rio De Janeiro
Structure-based design and biological profile of (E)-N-(4-Nitrobenzylidene)-2-naphthohydrazide, a novel small molecule inhibitor of I¿B kinase-ß.
Universidade Federal Do Rio De Janeiro
Synthesis, biological activity, and molecular modeling studies of 1H-1,2,3-triazole derivatives of carbohydrates as alpha-glucosidases inhibitors.
Universidade Federal Do Rio De Janeiro
Thrombin inhibition by novel benzamidine derivatives: a free-energy perturbation study.
Universidade Federal Do Rio De Janeiro
Identification of a novel ligand binding motif in the transthyretin channel.
Universidade Federal Do Rio De Janeiro
Studies towards the identification of putative bioactive conformation of potent vasodilator arylidene N-acylhydrazone derivatives.
Universidade Federal Do Rio De Janeiro
Novel 6-methanesulfonamide-3,4-methylenedioxyphenyl-N-acylhydrazones: orally effective anti-inflammatory drug candidates.
Universidade Federal Do Rio De Janeiro
Design, synthesis, and pharmacological profile of novel fused pyrazolo[4,3-d]pyridine and pyrazolo[3,4-b][1,8]naphthyridine isosteres: a new class of potent and selective acetylcholinesterase inhibitors.
Universidade Federal Do Rio De Janeiro
Discovery of sulfonyl hydrazone derivative as a new selective PDE4A and PDE4D inhibitor by lead-optimization approach on the prototype LASSBio-448: In vitro and in vivo preclinical studies.
Universidade Federal Do Rio De Janeiro
Synthesis and preliminary pharmacological evaluation of coumestans with different patterns of oxygenation.
Universidade Federal Do Rio De Janeiro
Phenylhydrazides as inhibitors of Leishmania amazonensis arginase and antileishmanial activity.
Universidade Federal Do Rio De Janeiro
Synthesis and pharmacological evaluation of new N-phenylpiperazine derivatives designed as homologues of the antipsychotic lead compound LASSBio-579.
Universidade Federal Do Rio De Janeiro
Docking, synthesis and pharmacological activity of novel urea-derivatives designed as p38 MAPK inhibitors.
Universidade Federal Do Rio De Janeiro
Development of a new methodology for screening of human immunodeficiency virus type 1 microbicides based on real-time PCR quantification.
Universidade Federal Do Rio De Janeiro
