Compile Data Set for Download or QSAR
Report error Found 53 Enz. Inhib. hit(s) with all data for entry = 50005558
Target5-hydroxytryptamine receptor 2A(Rat)
Universidade Federal Do Rio De Janeiro

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataIC50: 600nMAssay Description:Displacement of [3H]-ketanserin from 5HT2A receptor high affinity component in rat brain cortical membranes after 15 mins by competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Universidade Federal Do Rio De Janeiro

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataIC50: 1.30E+4nMAssay Description:Displacement of [3H]-ketanserin from 5HT2A receptor in rat brain cortical membranes after 15 mins by competition assay in presence of Gpp(NH)pMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Universidade Federal Do Rio De Janeiro

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataIC50: 3.06E+4nMAssay Description:Displacement of [3H]-ketanserin from 5HT2A receptor low affinity component in rat brain cortical membranes after 15 mins by competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Universidade Federal Do Rio De Janeiro

Curated by ChEMBL
LigandPNGBDBM50001884(8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b...)
Affinity DataKi:  21nMAssay Description:Displacement of [3H]-ketanserin from 5HT2A receptor in rat brain cortical membranes after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Rat)
Universidade Federal Do Rio De Janeiro

Curated by ChEMBL
LigandPNGBDBM50001884(8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b...)
Affinity DataKi:  22nMAssay Description:Displacement of [3H]-QNB from muscarinic receptor in rat brain cortical membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Universidade Federal Do Rio De Janeiro

Curated by ChEMBL
LigandPNGBDBM50001884(8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b...)
Affinity DataKi:  23nMAssay Description:Displacement of [3H]-mesulergine from human 5HT2C receptor after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Rat)
Universidade Federal Do Rio De Janeiro

Curated by ChEMBL
LigandPNGBDBM50001884(8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b...)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]-prozosin from alpha1B adrenoreceptor in rat liver membranes after 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Universidade Federal Do Rio De Janeiro

Curated by ChEMBL
LigandPNGBDBM50001884(8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b...)
Affinity DataKi:  60nMAssay Description:Displacement of [3H]-YM-09151-2 from human D4 receptor after 120 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Universidade Federal Do Rio De Janeiro

Curated by ChEMBL
LigandPNGBDBM50492801(CHEMBL2414357)
Affinity DataKi:  90nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5HT1A receptor in rat brain hippocampal membranes after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
LigandPNGBDBM50001884(8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b...)
Affinity DataKi:  100nMAssay Description:Displacement of [3H]-RX821002 from alpha2 adrenoreceptor in rat brain cortical membranes after 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Universidade Federal Do Rio De Janeiro

Curated by ChEMBL
LigandPNGBDBM50492799(CHEMBL2414354)
Affinity DataKi:  100nMAssay Description:Displacement of [3H]-YM-09151-2 from human D4 receptor after 120 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Universidade Federal Do Rio De Janeiro

Curated by ChEMBL
LigandPNGBDBM50492799(CHEMBL2414354)
Affinity DataKi:  110nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5HT1A receptor in rat brain hippocampal membranes after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Universidade Federal Do Rio De Janeiro

Curated by ChEMBL
LigandPNGBDBM50001884(8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b...)
Affinity DataKi:  140nMAssay Description:Displacement of [3H]-YM-09151-2 from D2 receptor in rat brain striatal membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Universidade Federal Do Rio De Janeiro

Curated by ChEMBL
LigandPNGBDBM50492800(CHEMBL2414358)
Affinity DataKi:  160nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5HT1A receptor in rat brain hippocampal membranes after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Universidade Federal Do Rio De Janeiro

Curated by ChEMBL
LigandPNGBDBM50308002(1-[(1-(4-Chlorophenyl)-1H-pyrazol-4-yl)methyl]-4-p...)
Affinity DataKi:  180nMAssay Description:Displacement of [3H]-YM-09151-2 from human D4 receptor after 120 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Universidade Federal Do Rio De Janeiro

Curated by ChEMBL
LigandPNGBDBM50492802(CHEMBL2414356)
Affinity DataKi:  180nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5HT1A receptor in rat brain hippocampal membranes after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Universidade Federal Do Rio De Janeiro

Curated by ChEMBL
LigandPNGBDBM50308002(1-[(1-(4-Chlorophenyl)-1H-pyrazol-4-yl)methyl]-4-p...)
Affinity DataKi:  220nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5HT1A receptor in rat brain hippocampal membranes after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Universidade Federal Do Rio De Janeiro

Curated by ChEMBL
LigandPNGBDBM50492801(CHEMBL2414357)
Affinity DataKi:  250nMAssay Description:Displacement of [3H]-YM-09151-2 from D2 receptor in rat brain striatal membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Universidade Federal Do Rio De Janeiro

Curated by ChEMBL
LigandPNGBDBM50001884(8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b...)
Affinity DataKi:  260nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5HT1A receptor in rat brain hippocampal membranes after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Universidade Federal Do Rio De Janeiro

Curated by ChEMBL
LigandPNGBDBM50492798(CHEMBL2414355)
Affinity DataKi:  310nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5HT1A receptor in rat brain hippocampal membranes after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Universidade Federal Do Rio De Janeiro

Curated by ChEMBL
LigandPNGBDBM50492802(CHEMBL2414356)
Affinity DataKi:  330nMAssay Description:Displacement of [3H]-YM-09151-2 from human D4 receptor after 120 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Rat)
Universidade Federal Do Rio De Janeiro

Curated by ChEMBL
LigandPNGBDBM50492800(CHEMBL2414358)
Affinity DataKi:  380nMAssay Description:Displacement of [3H]-prozosin from alpha1B adrenoreceptor in rat liver membranes after 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Universidade Federal Do Rio De Janeiro

Curated by ChEMBL
LigandPNGBDBM50308002(1-[(1-(4-Chlorophenyl)-1H-pyrazol-4-yl)methyl]-4-p...)
Affinity DataKi:  390nMAssay Description:Displacement of [3H]-YM-09151-2 from D2 receptor in rat brain striatal membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Rat)
Universidade Federal Do Rio De Janeiro

Curated by ChEMBL
LigandPNGBDBM50492798(CHEMBL2414355)
Affinity DataKi:  400nMAssay Description:Displacement of [3H]-prozosin from alpha1B adrenoreceptor in rat liver membranes after 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Universidade Federal Do Rio De Janeiro

Curated by ChEMBL
LigandPNGBDBM50492800(CHEMBL2414358)
Affinity DataKi:  490nMAssay Description:Displacement of [3H]-YM-09151-2 from D2 receptor in rat brain striatal membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Rat)
Universidade Federal Do Rio De Janeiro

Curated by ChEMBL
LigandPNGBDBM50492801(CHEMBL2414357)
Affinity DataKi:  570nMAssay Description:Displacement of [3H]-prozosin from alpha1B adrenoreceptor in rat liver membranes after 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Universidade Federal Do Rio De Janeiro

Curated by ChEMBL
LigandPNGBDBM50492802(CHEMBL2414356)
Affinity DataKi:  600nMAssay Description:Displacement of [3H]-ketanserin from 5HT2A receptor in rat brain cortical membranes after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
LigandPNGBDBM50492801(CHEMBL2414357)
Affinity DataKi:  610nMAssay Description:Displacement of [3H]-RX821002 from alpha2 adrenoreceptor in rat brain cortical membranes after 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Universidade Federal Do Rio De Janeiro

Curated by ChEMBL
LigandPNGBDBM50492798(CHEMBL2414355)
Affinity DataKi:  650nMAssay Description:Displacement of [3H]-ketanserin from 5HT2A receptor in rat brain cortical membranes after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Universidade Federal Do Rio De Janeiro

Curated by ChEMBL
LigandPNGBDBM50492801(CHEMBL2414357)
Affinity DataKi:  650nMAssay Description:Displacement of [3H]-ketanserin from 5HT2A receptor in rat brain cortical membranes after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Universidade Federal Do Rio De Janeiro

Curated by ChEMBL
LigandPNGBDBM50492802(CHEMBL2414356)
Affinity DataKi:  680nMAssay Description:Displacement of [3H]-YM-09151-2 from D2 receptor in rat brain striatal membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Rat)
Universidade Federal Do Rio De Janeiro

Curated by ChEMBL
LigandPNGBDBM50492802(CHEMBL2414356)
Affinity DataKi:  700nMAssay Description:Displacement of [3H]-prozosin from alpha1B adrenoreceptor in rat liver membranes after 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Universidade Federal Do Rio De Janeiro

Curated by ChEMBL
LigandPNGBDBM50492798(CHEMBL2414355)
Affinity DataKi:  790nMAssay Description:Displacement of [3H]-YM-09151-2 from D2 receptor in rat brain striatal membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Universidade Federal Do Rio De Janeiro

Curated by ChEMBL
LigandPNGBDBM50492801(CHEMBL2414357)
Affinity DataKi:  800nMAssay Description:Displacement of [3H]-YM-09151-2 from human D4 receptor after 120 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Rat)
Universidade Federal Do Rio De Janeiro

Curated by ChEMBL
LigandPNGBDBM50492799(CHEMBL2414354)
Affinity DataKi:  850nMAssay Description:Displacement of [3H]-prozosin from alpha1B adrenoreceptor in rat liver membranes after 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Universidade Federal Do Rio De Janeiro

Curated by ChEMBL
LigandPNGBDBM50492800(CHEMBL2414358)
Affinity DataKi:  950nMAssay Description:Displacement of [3H]-ketanserin from 5HT2A receptor in rat brain cortical membranes after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Universidade Federal Do Rio De Janeiro

Curated by ChEMBL
LigandPNGBDBM50492800(CHEMBL2414358)
Affinity DataKi:  1.18E+3nMAssay Description:Displacement of [3H]-YM-09151-2 from human D4 receptor after 120 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
LigandPNGBDBM50492800(CHEMBL2414358)
Affinity DataKi:  1.40E+3nMAssay Description:Displacement of [3H]-RX821002 from alpha2 adrenoreceptor in rat brain cortical membranes after 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Universidade Federal Do Rio De Janeiro

Curated by ChEMBL
LigandPNGBDBM50492798(CHEMBL2414355)
Affinity DataKi:  1.50E+3nMAssay Description:Displacement of [3H]-YM-09151-2 from human D4 receptor after 120 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
LigandPNGBDBM50492802(CHEMBL2414356)
Affinity DataKi:  1.60E+3nMAssay Description:Displacement of [3H]-RX821002 from alpha2 adrenoreceptor in rat brain cortical membranes after 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Universidade Federal Do Rio De Janeiro

Curated by ChEMBL
LigandPNGBDBM50492799(CHEMBL2414354)
Affinity DataKi:  1.90E+3nMAssay Description:Displacement of [3H]-YM-09151-2 from D2 receptor in rat brain striatal membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
LigandPNGBDBM50492799(CHEMBL2414354)
Affinity DataKi:  2.10E+3nMAssay Description:Displacement of [3H]-RX821002 from alpha2 adrenoreceptor in rat brain cortical membranes after 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Universidade Federal Do Rio De Janeiro

Curated by ChEMBL
LigandPNGBDBM50492799(CHEMBL2414354)
Affinity DataKi:  2.49E+3nMAssay Description:Displacement of [3H]-ketanserin from 5HT2A receptor in rat brain cortical membranes after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
LigandPNGBDBM50308002(1-[(1-(4-Chlorophenyl)-1H-pyrazol-4-yl)methyl]-4-p...)
Affinity DataKi:  2.50E+3nMAssay Description:Displacement of [3H]-RX821002 from alpha2 adrenoreceptor in rat brain cortical membranes after 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Rat)
Universidade Federal Do Rio De Janeiro

Curated by ChEMBL
LigandPNGBDBM50308002(1-[(1-(4-Chlorophenyl)-1H-pyrazol-4-yl)methyl]-4-p...)
Affinity DataKi:  2.60E+3nMAssay Description:Displacement of [3H]-prozosin from alpha1B adrenoreceptor in rat liver membranes after 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Universidade Federal Do Rio De Janeiro

Curated by ChEMBL
LigandPNGBDBM50492798(CHEMBL2414355)
Affinity DataKi:  2.80E+3nMAssay Description:Displacement of [3H]-mesulergine from human 5HT2C receptor after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
LigandPNGBDBM50492798(CHEMBL2414355)
Affinity DataKi:  2.80E+3nMAssay Description:Displacement of [3H]-RX821002 from alpha2 adrenoreceptor in rat brain cortical membranes after 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Universidade Federal Do Rio De Janeiro

Curated by ChEMBL
LigandPNGBDBM50492802(CHEMBL2414356)
Affinity DataKi:  5.10E+3nMAssay Description:Displacement of [3H]-mesulergine from human 5HT2C receptor after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Universidade Federal Do Rio De Janeiro

Curated by ChEMBL
LigandPNGBDBM50492801(CHEMBL2414357)
Affinity DataKi:  5.90E+3nMAssay Description:Displacement of [3H]-mesulergine from human 5HT2C receptor after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Universidade Federal Do Rio De Janeiro

Curated by ChEMBL
LigandPNGBDBM50308002(1-[(1-(4-Chlorophenyl)-1H-pyrazol-4-yl)methyl]-4-p...)
Affinity DataKi:  6.91E+3nMAssay Description:Displacement of [3H]-ketanserin from 5HT2A receptor in rat brain cortical membranes after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
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