Binding Database

BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 748K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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25 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review

PMID

Data

Article Title

Organization

Synthesis and biological evaluation of 1-(4-(piperazin-1-yl)phenyl)pyridin-2(1H)-one derivatives as potential SSRIs.

Sunshine Lake Pharma

Design, synthesis and biological evaluation of pyridinylmethylenepiperidine derivatives as potent 5-HT

Sunshine Lake Pharma

Computational Fragment-Based Design Facilitates Discovery of Potent and Selective Monoamine Oxidase-B (MAO-B) Inhibitor.

Sunshine Lake Pharma

Discovery of hepatitis B virus capsid assembly inhibitors leading to a heteroaryldihydropyrimidine based clinical candidate (GLS4).

Sunshine Lake Pharma

CD73 inhibitors

Oric Pharmaceuticals

Tricyclic inhibitors of poly(ADP-ribose)polymerase

Rakovina Therapeutics

Methods and compositions of inhibiting DCN1-UBC12 interaction

Memorial Sloan Kettering Cancer Center

Aminopyrimidinyl compounds

Pfizer

Imidazolonylquinolines and the use thereof as ATM kinase inhibitors

Merck Patent

Biaryl kinase inhibitors

Bristol-Myers Squibb

Imidazopyridine compounds

Astellas Pharma

Chromone containing sulfonamides as potent carbonic anhydrase inhibitors.

Ondokuz Mayis University

Synthesis and biological evaluation of novel N, N'-disubstituted urea and thiourea derivatives as potential anti-melanoma agents.

Nanjing University

Sulfur-containing heterocyclic derivative having Beta secretase inhibitory activity

Shionogi

Synthetic methods for spiro-oxindole compounds

Xenon Pharmaceuticals

Substituted hetero-bicyclic compounds, compositions and medicinal applications thereof

Advinus Therapeutics

Spiro compounds useful as inhibitors of stearoyl-coenzyme A delta-9 desaturase

Merck Canada

Pyridone amides as modulators of sodium channels

Vertex Pharmaceuticals

BACE inhibitors

Eli Lilly

Plant-derived flavones as inhibitors of aurora B kinase and their quantitative structure-activity relationships.

Konkuk University

Method of treating contrast-induced nephropathy

Novartis

Tyrosine kinase inhibitors

Chembridge

Functional calcitonin gene-related peptide subtype 2 receptors in porcine coronary arteries are identified as calcitonin gene-related peptide subtype 1 receptors by radioligand binding and reverse transcription-polymerase chain reaction.

Creighton University

Synthesis and in vitro Evaluation of Novel Indole-Based Sigma Receptors Ligands.

Yeditepe University