23 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
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Article Title
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Discovery of novel small molecule inhibitors of lysine methyltransferase G9a and their mechanism in leukemia cell lines.
Georgia State University
Synthesis and evaluation of 2,5 and 2,6 pyridine-based CXCR4 inhibitors.
Georgia State University
Discovery of selective inhibitors of tyrosyl-DNA phosphodiesterase 2 by targeting the enzyme DNA-binding cleft.
Georgia State University
Design, synthesis and biological evaluation of di-substituted noscapine analogs as potent and microtubule-targeted anticancer agents.
Georgia State University
Pharmacophore-based virtual screening and biological evaluation of small molecule inhibitors for protein arginine methylation.
Georgia State University
Synthesis and evaluation of carbocyanine dyes as PRMT inhibitors and imaging agents.
Georgia State University
Discovery and mechanistic study of a class of protein arginine methylation inhibitors.
Georgia State University
Design, synthesis, and structure-activity relationship, molecular modeling, and NMR studies of a series of phenyl alkyl ketones as highly potent and selective phosphodiesterase-4 inhibitors.
Georgia State University
Pyrogallol and its analogs can antagonize bacterial quorum sensing in Vibrio harveyi.
Georgia State University
Inhibition of the Ubiquitin Transfer Cascade by a Peptidomimetic Foldamer Mimicking the E2 N-Terminal Helix.
Georgia State University
Developments of small molecules as inhibitors for carbonic anhydrase isoforms.
Georgia State University
Evaluation of small molecule SecA inhibitors against methicillin-resistant Staphylococcus aureus.
Georgia State University
Substituted Bis-THF Protease Inhibitors with Improved Potency against Highly Resistant Mature HIV-1 Protease PR20.
Georgia State University
Novel P2 tris-tetrahydrofuran group in antiviral compound 1 (GRL-0519) fills the S2 binding pocket of selected mutants of HIV-1 protease.
Georgia State University
Potent antiviral HIV-1 protease inhibitor GRL-02031 adapts to the structures of drug resistant mutants with its P1'-pyrrolidinone ring.
Georgia State University
Design and synthesis of novel small-molecule inhibitors of the hypoxia inducible factor pathway.
Georgia State University
Solution kinetics measurements suggest HIV-1 protease has two binding sites for darunavir and amprenavir.
Georgia State University
Potent new antiviral compound shows similar inhibition and structural interactions with drug resistant mutants and wild type HIV-1 protease.
Georgia State University
