Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50040612
TargetHistone H4(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50397030(CHEMBL2171189)
Affinity DataKd:  2.38E+4nMAssay Description:Binding affinity to fluorescein-labeled Histone H4(1-20) by spectrofluorometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 1 [11-371](Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50397030(CHEMBL2171189)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of histidine tagged recombinant PRMT1 expressed in Escherichia coli BL21 (DE3) cells using Histone H4(1-20) substrate preincubated for 5 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50397030(CHEMBL2171189)
Affinity DataIC50: 1.52E+4nMAssay Description:Inhibition of recombinant p300 HAT domain using Histone H4(1-20) substrate assessed as inhibition of histone acetyltransferase activity after 10 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 1 [11-371](Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50328743(3-((4-acetamidophenyl)diazenyl)-4-hydroxy-7-(3-(5-...)
Affinity DataIC50: 2.05E+4nMAssay Description:Inhibition of histidine tagged recombinant PRMT1 expressed in Escherichia coli BL21 (DE3) cells using Histone H4(1-20) substrate preincubated for 5 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 1 [11-371](Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50397031(CHEMBL2171190)
Affinity DataIC50: 4.17E+4nMAssay Description:Inhibition of histidine tagged recombinant PRMT1 expressed in Escherichia coli BL21 (DE3) cells using Histone H4(1-20) substrate preincubated for 5 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 1 [11-371](Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50206427(AMI-1 | 7,7'-carbonylbis(azanediyl)bis(4-hydroxyna...)
Affinity DataIC50: 7.69E+4nMAssay Description:Inhibition of histidine tagged recombinant PRMT1 expressed in Escherichia coli BL21 (DE3) cells using Histone H4(1-20) substrate preincubated for 5 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 1 [11-371](Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50397031(CHEMBL2171190)
Affinity DataKi:  8.40E+3nMAssay Description:Competitive inhibition of histidine tagged recombinant PRMT1 expressed in Escherichia coli BL21 (DE3) cells assessed as Ki intercept using Histone H4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 1 [11-371](Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50397030(CHEMBL2171189)
Affinity DataKi:  1.13E+4nMAssay Description:Competitive inhibition of histidine tagged recombinant PRMT1 expressed in Escherichia coli BL21 (DE3) cells assessed as Ki intercept using Histone H4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 1 [11-371](Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50397030(CHEMBL2171189)
Affinity DataKi:  2.97E+4nMAssay Description:Non competitive inhibition of histidine tagged recombinant PRMT1 expressed in Escherichia coli BL21 (DE3) cells assessed as Ki slope using SAM preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 1 [11-371](Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50397031(CHEMBL2171190)
Affinity DataKi: >2.57E+5nMAssay Description:Non competitive inhibition of histidine tagged recombinant PRMT1 expressed in Escherichia coli BL21 (DE3) cells assessed as Ki slope using SAM preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed