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Report error Found 28 of affinity data for UniProtKB/TrEMBL: P22079
TargetLactoperoxidase(Human)
Esgelbio

US Patent
LigandPNGBDBM707363(US20240408072, Compound NE-2-6)
Affinity DataIC50: 13nMAssay Description:The screening of compounds for MPO inhibition activity was conducted in three stages. The inhibitory activity of each compound against MPO was assess...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetLactoperoxidase(Human)
Esgelbio

US Patent
LigandPNGBDBM707365(US20240408072, Compound NE-2-8)
Affinity DataIC50: 16nMAssay Description:The screening of compounds for MPO inhibition activity was conducted in three stages. The inhibitory activity of each compound against MPO was assess...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetLactoperoxidase(Human)
Esgelbio

US Patent
LigandPNGBDBM707364(US20240408072, Compound NE-2-7)
Affinity DataIC50: 20nMAssay Description:The screening of compounds for MPO inhibition activity was conducted in three stages. The inhibitory activity of each compound against MPO was assess...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetLactoperoxidase(Human)
Esgelbio

US Patent
LigandPNGBDBM50133597(CHEBI:8502 | Propacil | Propylthiouracil | Prothyr...)
Affinity DataIC50: 119nMAssay Description:The screening of compounds for MPO inhibition activity was conducted in three stages. The inhibitory activity of each compound against MPO was assess...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetLactoperoxidase(Human)
Esgelbio

US Patent
LigandPNGBDBM707366(US20240408072, Compound NE-2-9)
Affinity DataIC50: 130nMAssay Description:The screening of compounds for MPO inhibition activity was conducted in three stages. The inhibitory activity of each compound against MPO was assess...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetLactoperoxidase(Human)
Esgelbio

US Patent
LigandPNGBDBM50241361(CHEMBL1515 | METHIMAZOLE | US9138393, Methimazole ...)
Affinity DataIC50: 510nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetLactoperoxidase(Human)
Esgelbio

US Patent
LigandPNGBDBM50638126(CHEMBL5517779)
Affinity DataIC50: 590nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetLactoperoxidase(Human)
Esgelbio

US Patent
LigandPNGBDBM50239994(CHEBI:82346 | Methylthiouracil)
Affinity DataIC50: 1.49E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetLactoperoxidase(Human)
Esgelbio

US Patent
LigandPNGBDBM50638128(CHEMBL5555319)
Affinity DataIC50: 2.20E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetLactoperoxidase(Human)
Esgelbio

US Patent
LigandPNGBDBM50638130(CHEMBL5560226)
Affinity DataIC50: 5.50E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetLactoperoxidase(Human)
Esgelbio

US Patent
LigandPNGBDBM50638124(CHEMBL5557885)
Affinity DataIC50: 7.30E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetLactoperoxidase(Human)
Esgelbio

US Patent
LigandPNGBDBM50133597(CHEBI:8502 | Propacil | Propylthiouracil | Prothyr...)
Affinity DataIC50: 7.52E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetLactoperoxidase(Human)
Esgelbio

US Patent
LigandPNGBDBM50507390(CHEMBL4482878 | US10981879, Example 3)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of human LPO assessed as reduction in H2O2 catalyzed 3,5-iodo tyrosine formation from 3-iodotyrosine and potassium iodide preincubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetLactoperoxidase(Human)
Esgelbio

US Patent
LigandPNGBDBM50275890(ethyl 2,3-dihydro-3-methyl-2-selenoxoimidazole-1-c...)
Affinity DataIC50: 1.01E+4nMAssay Description:Inhibition of lactoperoxidase-catalyzed iodination of L-tyrosine assessed as 3,5-diiodo-L-tyrosine formation by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetLactoperoxidase(Human)
Esgelbio

US Patent
LigandPNGBDBM50275889(carbimazole | CHEMBL508102)
Affinity DataIC50: 1.04E+4nMAssay Description:Inhibition of lactoperoxidase-catalyzed iodination of L-tyrosine assessed as 3,5-diiodo-L-tyrosine formation by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetLactoperoxidase(Human)
Esgelbio

US Patent
LigandPNGBDBM50275891(methyl 3-methyl-2-thioxo-2,3-dihydro-1H-imidazole-...)
Affinity DataIC50: 1.07E+4nMAssay Description:Inhibition of lactoperoxidase-catalyzed iodination of L-tyrosine assessed as 3,5-diiodo-L-tyrosine formation by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetLactoperoxidase(Human)
Esgelbio

US Patent
LigandPNGBDBM50241361(CHEMBL1515 | METHIMAZOLE | US9138393, Methimazole ...)
Affinity DataIC50: 1.18E+4nMAssay Description:Inhibition of lactoperoxidase-catalyzed iodination of L-tyrosine assessed as 3,5-diiodo-L-tyrosine formation by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetLactoperoxidase(Human)
Esgelbio

US Patent
LigandPNGBDBM50275895(methyl 3-ethyl-2-thioxo-2,3-dihydro-1H-imidazole-1...)
Affinity DataIC50: 1.96E+4nMAssay Description:Inhibition of lactoperoxidase-catalyzed iodination of L-tyrosine assessed as 3,5-diiodo-L-tyrosine formation by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetLactoperoxidase(Human)
Esgelbio

US Patent
LigandPNGBDBM50275892(methyl 3-methyl-2-selenoxo-2,3-dihydro-1H-imidazol...)
Affinity DataIC50: 1.97E+4nMAssay Description:Inhibition of lactoperoxidase-catalyzed iodination of L-tyrosine assessed as 3,5-diiodo-L-tyrosine formation by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetLactoperoxidase(Human)
Esgelbio

US Patent
LigandPNGBDBM50275893(ethyl 3-ethyl-2-thioxo-2,3-dihydro-1H-imidazole-1-...)
Affinity DataIC50: 2.05E+4nMAssay Description:Inhibition of lactoperoxidase-catalyzed iodination of L-tyrosine assessed as 3,5-diiodo-L-tyrosine formation by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetLactoperoxidase(Human)
Esgelbio

US Patent
LigandPNGBDBM50275894(ethyl 3-ethyl-2-selenoxo-2,3-dihydro-1H-imidazole-...)
Affinity DataIC50: 2.13E+4nMAssay Description:Inhibition of lactoperoxidase-catalyzed iodination of L-tyrosine assessed as 3,5-diiodo-L-tyrosine formation by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetLactoperoxidase(Human)
Esgelbio

US Patent
LigandPNGBDBM50638125(CHEMBL5557030)
Affinity DataIC50: 2.31E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetLactoperoxidase(Human)
Esgelbio

US Patent
LigandPNGBDBM50275944(methyl 3-ethyl-2-selenoxo-2,3-dihydro-1H-imidazole...)
Affinity DataIC50: 2.53E+4nMAssay Description:Inhibition of lactoperoxidase-catalyzed iodination of L-tyrosine assessed as 3,5-diiodo-L-tyrosine formation by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetLactoperoxidase(Human)
Esgelbio

US Patent
LigandPNGBDBM50638127(CHEMBL5558431)
Affinity DataIC50: 3.87E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetLactoperoxidase(Human)
Esgelbio

US Patent
LigandPNGBDBM50554035(CHEMBL4790231)
Affinity DataIC50: 6.20E+4nMAssay Description:Inhibition of LPO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetLactoperoxidase(Human)
Esgelbio

US Patent
LigandPNGBDBM50554034(CHEMBL4747269)
Affinity DataIC50: 6.20E+4nMAssay Description:Inhibition of LPO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetLactoperoxidase(Human)
Esgelbio

US Patent
LigandPNGBDBM50106515(7-Benzyloxy-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-y...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human LPO assessed as reduction in H2O2 catalyzed 3,5-iodo tyrosine formation from 3-iodotyrosine and potassium iodide preincubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetLactoperoxidase(Human)
Esgelbio

US Patent
LigandPNGBDBM50638129(CHEMBL5561937)
Affinity DataIC50: 1.37E+5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed