Compile Data Set for Download or QSAR
Report error Found 1444 of affinity data for UniProtKB/TrEMBL: Q9QYJ6
LigandPNGBDBM50365964(CHEMBL2070530 | CHEMBL1956235)
Affinity DataKd:  0.940nMAssay Description:Binding affinity to PDE10A in Sprague-Dawley rat striatum by TopCount analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
LigandPNGBDBM290889(US9579407, Example 00162 | 1-[2-fluoro-4- (tetrahy...)
Affinity DataKd:  12nMAssay Description:Binding affinity to PDE10A in rat brain caudate-putamen by saturation binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandPNGBDBM290889(US9579407, Example 00162 | 1-[2-fluoro-4- (tetrahy...)
Affinity DataKd:  4.70nMAssay Description:Binding affinity to PDE10A in rat brain nucleus accumbens by saturation binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandPNGBDBM50496800(CHEMBL3218036)
Affinity DataKd:  1.30nMAssay Description:Binding affinity to PDE10A in rat striatum homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandPNGBDBM115431(US8637500, 455 | US8637500, 454 | US8637500, 301)
Affinity DataIC50: 0.0400nMT: 2°CAssay Description:An IMAP TR-FRET assay was used to analyze the enzyme activity (Molecular Devices Corp., Sunnyvale Calif.). 5 μL of serial diluted PDE10A (BPS Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
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LigandPNGBDBM115430(US8637500, 299)
Affinity DataIC50: 0.0450nMT: 2°CAssay Description:An IMAP TR-FRET assay was used to analyze the enzyme activity (Molecular Devices Corp., Sunnyvale Calif.). 5 μL of serial diluted PDE10A (BPS Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
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LigandPNGBDBM115427(US8637500, 296)
Affinity DataIC50: 0.0550nMT: 2°CAssay Description:An IMAP TR-FRET assay was used to analyze the enzyme activity (Molecular Devices Corp., Sunnyvale Calif.). 5 μL of serial diluted PDE10A (BPS Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
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LigandPNGBDBM115428(US8637500, 297)
Affinity DataIC50: 0.0560nMT: 2°CAssay Description:An IMAP TR-FRET assay was used to analyze the enzyme activity (Molecular Devices Corp., Sunnyvale Calif.). 5 μL of serial diluted PDE10A (BPS Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
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LigandPNGBDBM142557(US8933224, 150)
Affinity DataIC50: 0.0697nMpH: 7.5Assay Description:The ability of a compound to inhibit PDE10 enzymatic activity can be demonstrated by any number of assays that are known in the art. The products of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2015
Entry Details
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LigandPNGBDBM142550(US8933224, 144 | US8933224, 143)
Affinity DataIC50: 0.0837nMpH: 7.5Assay Description:The ability of a compound to inhibit PDE10 enzymatic activity can be demonstrated by any number of assays that are known in the art. The products of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2015
Entry Details
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LigandPNGBDBM142481(US8933224, 74)
Affinity DataIC50: 0.0896nMpH: 7.5Assay Description:The ability of a compound to inhibit PDE10 enzymatic activity can be demonstrated by any number of assays that are known in the art. The products of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2015
Entry Details
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LigandPNGBDBM142544(US8933224, 137)
Affinity DataIC50: 0.0950nMpH: 7.5Assay Description:The ability of a compound to inhibit PDE10 enzymatic activity can be demonstrated by any number of assays that are known in the art. The products of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2015
Entry Details
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LigandPNGBDBM115424(US8637500, 293)
Affinity DataIC50: 0.0980nMT: 2°CAssay Description:An IMAP TR-FRET assay was used to analyze the enzyme activity (Molecular Devices Corp., Sunnyvale Calif.). 5 μL of serial diluted PDE10A (BPS Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
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LigandPNGBDBM142536(US8933224, 129)
Affinity DataIC50: 0.0998nMpH: 7.5Assay Description:The ability of a compound to inhibit PDE10 enzymatic activity can be demonstrated by any number of assays that are known in the art. The products of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2015
Entry Details
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LigandPNGBDBM142459(US8933224, 52)
Affinity DataIC50: 0.101nMpH: 7.5Assay Description:The ability of a compound to inhibit PDE10 enzymatic activity can be demonstrated by any number of assays that are known in the art. The products of ...More data for this Ligand-Target Pair
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Date in BDB:
6/8/2015
Entry Details
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LigandPNGBDBM142451(US8933224, 44)
Affinity DataIC50: 0.102nMpH: 7.5Assay Description:The ability of a compound to inhibit PDE10 enzymatic activity can be demonstrated by any number of assays that are known in the art. The products of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2015
Entry Details
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LigandPNGBDBM142550(US8933224, 144 | US8933224, 143)
Affinity DataIC50: 0.106nMpH: 7.5Assay Description:The ability of a compound to inhibit PDE10 enzymatic activity can be demonstrated by any number of assays that are known in the art. The products of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2015
Entry Details
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LigandPNGBDBM142442(US8933224, 35)
Affinity DataIC50: 0.123nMpH: 7.5Assay Description:The ability of a compound to inhibit PDE10 enzymatic activity can be demonstrated by any number of assays that are known in the art. The products of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2015
Entry Details
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LigandPNGBDBM142555(US8933224, 148)
Affinity DataIC50: 0.125nMpH: 7.5Assay Description:The ability of a compound to inhibit PDE10 enzymatic activity can be demonstrated by any number of assays that are known in the art. The products of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2015
Entry Details
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LigandPNGBDBM142559(US8933224, 152)
Affinity DataIC50: 0.130nMpH: 7.5Assay Description:The ability of a compound to inhibit PDE10 enzymatic activity can be demonstrated by any number of assays that are known in the art. The products of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2015
Entry Details
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LigandPNGBDBM115425(US8637500, 294)
Affinity DataIC50: 0.132nMT: 2°CAssay Description:An IMAP TR-FRET assay was used to analyze the enzyme activity (Molecular Devices Corp., Sunnyvale Calif.). 5 μL of serial diluted PDE10A (BPS Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
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LigandPNGBDBM142493(US8933224, 86)
Affinity DataIC50: 0.132nMpH: 7.5Assay Description:The ability of a compound to inhibit PDE10 enzymatic activity can be demonstrated by any number of assays that are known in the art. The products of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2015
Entry Details
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LigandPNGBDBM142446(US8933224, 173 | US8933224, 39)
Affinity DataIC50: 0.136nMpH: 7.5Assay Description:The ability of a compound to inhibit PDE10 enzymatic activity can be demonstrated by any number of assays that are known in the art. The products of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2015
Entry Details
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LigandPNGBDBM142548(US8933224, 141)
Affinity DataIC50: 0.142nMpH: 7.5Assay Description:The ability of a compound to inhibit PDE10 enzymatic activity can be demonstrated by any number of assays that are known in the art. The products of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2015
Entry Details
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LigandPNGBDBM142561(US8933224, 154)
Affinity DataIC50: 0.144nMpH: 7.5Assay Description:The ability of a compound to inhibit PDE10 enzymatic activity can be demonstrated by any number of assays that are known in the art. The products of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2015
Entry Details
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LigandPNGBDBM142425(US8933224, 18)
Affinity DataIC50: 0.147nMpH: 7.5Assay Description:The ability of a compound to inhibit PDE10 enzymatic activity can be demonstrated by any number of assays that are known in the art. The products of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2015
Entry Details
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LigandPNGBDBM142519(US8933224, 112)
Affinity DataIC50: 0.147nMpH: 7.5Assay Description:The ability of a compound to inhibit PDE10 enzymatic activity can be demonstrated by any number of assays that are known in the art. The products of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2015
Entry Details
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LigandPNGBDBM142568(US8933224, 161)
Affinity DataIC50: 0.163nMpH: 7.5Assay Description:The ability of a compound to inhibit PDE10 enzymatic activity can be demonstrated by any number of assays that are known in the art. The products of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2015
Entry Details
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LigandPNGBDBM115429(US8637500, 298)
Affinity DataIC50: 0.171nMT: 2°CAssay Description:An IMAP TR-FRET assay was used to analyze the enzyme activity (Molecular Devices Corp., Sunnyvale Calif.). 5 μL of serial diluted PDE10A (BPS Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
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LigandPNGBDBM142562(US8933224, 155)
Affinity DataIC50: 0.171nMpH: 7.5Assay Description:The ability of a compound to inhibit PDE10 enzymatic activity can be demonstrated by any number of assays that are known in the art. The products of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2015
Entry Details
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LigandPNGBDBM142593(US8933224, 11)
Affinity DataIC50: 0.174nMpH: 7.5Assay Description:The ability of a compound to inhibit PDE10 enzymatic activity can be demonstrated by any number of assays that are known in the art. The products of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2015
Entry Details
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LigandPNGBDBM142444(US8933224, 132 | US8933224, 37)
Affinity DataIC50: 0.174nMpH: 7.5Assay Description:The ability of a compound to inhibit PDE10 enzymatic activity can be demonstrated by any number of assays that are known in the art. The products of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2015
Entry Details
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LigandPNGBDBM142448(US8933224, 41)
Affinity DataIC50: 0.175nMpH: 7.5Assay Description:The ability of a compound to inhibit PDE10 enzymatic activity can be demonstrated by any number of assays that are known in the art. The products of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2015
Entry Details
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LigandPNGBDBM142444(US8933224, 132 | US8933224, 37)
Affinity DataIC50: 0.177nMpH: 7.5Assay Description:The ability of a compound to inhibit PDE10 enzymatic activity can be demonstrated by any number of assays that are known in the art. The products of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2015
Entry Details
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LigandPNGBDBM31592(PF-2545920 | substituted pyrazole, 9 | US9138494, ...)
Affinity DataIC50: 0.180nMAssay Description:Inhibition of rat PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
LigandPNGBDBM115422(US8637500, 291)
Affinity DataIC50: 0.189nMT: 2°CAssay Description:An IMAP TR-FRET assay was used to analyze the enzyme activity (Molecular Devices Corp., Sunnyvale Calif.). 5 μL of serial diluted PDE10A (BPS Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
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LigandPNGBDBM142446(US8933224, 173 | US8933224, 39)
Affinity DataIC50: 0.193nMpH: 7.5Assay Description:The ability of a compound to inhibit PDE10 enzymatic activity can be demonstrated by any number of assays that are known in the art. The products of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2015
Entry Details
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LigandPNGBDBM142594(US8933224, 12)
Affinity DataIC50: 0.194nMpH: 7.5Assay Description:The ability of a compound to inhibit PDE10 enzymatic activity can be demonstrated by any number of assays that are known in the art. The products of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2015
Entry Details
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LigandPNGBDBM142564(US8933224, 157)
Affinity DataIC50: 0.196nMpH: 7.5Assay Description:The ability of a compound to inhibit PDE10 enzymatic activity can be demonstrated by any number of assays that are known in the art. The products of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2015
Entry Details
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LigandPNGBDBM99011(US8497265, 467)
Affinity DataIC50: 0.200nMAssay Description:Enzyme activity: An IMAP TR-FRET assay was used to analyze the enzyme activity (Molecular Devices Corp., Sunnyvale, Calif). More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2013
Entry Details
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LigandPNGBDBM142586(US8933224, 4)
Affinity DataIC50: 0.205nMpH: 7.5Assay Description:The ability of a compound to inhibit PDE10 enzymatic activity can be demonstrated by any number of assays that are known in the art. The products of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2015
Entry Details
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LigandPNGBDBM142565(US8933224, 158)
Affinity DataIC50: 0.227nMpH: 7.5Assay Description:The ability of a compound to inhibit PDE10 enzymatic activity can be demonstrated by any number of assays that are known in the art. The products of ...More data for this Ligand-Target Pair
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Date in BDB:
6/8/2015
Entry Details
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LigandPNGBDBM98900(US8497265, 226)
Affinity DataIC50: 0.229nMAssay Description:Enzyme activity: An IMAP TR-FRET assay was used to analyze the enzyme activity (Molecular Devices Corp., Sunnyvale, Calif). More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2013
Entry Details
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LigandPNGBDBM142527(US8933224, 120)
Affinity DataIC50: 0.233nMpH: 7.5Assay Description:The ability of a compound to inhibit PDE10 enzymatic activity can be demonstrated by any number of assays that are known in the art. The products of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2015
Entry Details
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LigandPNGBDBM142435(US8933224, 28)
Affinity DataIC50: 0.236nMpH: 7.5Assay Description:The ability of a compound to inhibit PDE10 enzymatic activity can be demonstrated by any number of assays that are known in the art. The products of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2015
Entry Details
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LigandPNGBDBM142424(US8933224, 17)
Affinity DataIC50: 0.240nMpH: 7.5Assay Description:The ability of a compound to inhibit PDE10 enzymatic activity can be demonstrated by any number of assays that are known in the art. The products of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2015
Entry Details
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LigandPNGBDBM142479(US8933224, 72)
Affinity DataIC50: 0.255nMpH: 7.5Assay Description:The ability of a compound to inhibit PDE10 enzymatic activity can be demonstrated by any number of assays that are known in the art. The products of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2015
Entry Details
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LigandPNGBDBM142543(US8933224, 136)
Affinity DataIC50: 0.265nMpH: 7.5Assay Description:The ability of a compound to inhibit PDE10 enzymatic activity can be demonstrated by any number of assays that are known in the art. The products of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2015
Entry Details
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LigandPNGBDBM142546(US8933224, 139)
Affinity DataIC50: 0.270nMpH: 7.5Assay Description:The ability of a compound to inhibit PDE10 enzymatic activity can be demonstrated by any number of assays that are known in the art. The products of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2015
Entry Details
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LigandPNGBDBM142508(US8933224, 101)
Affinity DataIC50: 0.283nMpH: 7.5Assay Description:The ability of a compound to inhibit PDE10 enzymatic activity can be demonstrated by any number of assays that are known in the art. The products of ...More data for this Ligand-Target Pair
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Date in BDB:
6/8/2015
Entry Details
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