Compile Data Set for Download or QSAR
Report error Found 23 of affinity data for UniProtKB/TrEMBL: Q9QVP9
TargetProtein-tyrosine kinase 2-beta(Mouse)
Amgen

Curated by ChEMBL
LigandPNGBDBM50301356(N-(5-(6,7-dimethoxyquinolin-4-yloxy)pyridin-2-yl)-...)
Affinity DataEC50:  10nMAssay Description:Inhibition of mouse Pyk2 in MC3TC3 cells assessed as increase in alkaline phosphatase levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetProtein-tyrosine kinase 2-beta(Mouse)
Amgen

Curated by ChEMBL
LigandPNGBDBM50301356(N-(5-(6,7-dimethoxyquinolin-4-yloxy)pyridin-2-yl)-...)
Affinity DataEC50:  10nMAssay Description:Inhibition of mouse Pyk2 in MC3TC3 cells assessed as increase in calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetProtein-tyrosine kinase 2-beta(Mouse)
Amgen

Curated by ChEMBL
LigandPNGBDBM50301364(N-(5-(6,7-dimethoxyquinolin-4-yloxy)pyridin-2-yl)-...)
Affinity DataEC50:  10nMAssay Description:Inhibition of mouse Pyk2 in MC3TC3 cells assessed as increase in calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetProtein-tyrosine kinase 2-beta(Mouse)
Amgen

Curated by ChEMBL
LigandPNGBDBM50301364(N-(5-(6,7-dimethoxyquinolin-4-yloxy)pyridin-2-yl)-...)
Affinity DataEC50:  10nMAssay Description:Inhibition of mouse Pyk2 in MC3TC3 cells assessed as increase in osteocalcin levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetProtein-tyrosine kinase 2-beta(Mouse)
Amgen

Curated by ChEMBL
LigandPNGBDBM50301364(N-(5-(6,7-dimethoxyquinolin-4-yloxy)pyridin-2-yl)-...)
Affinity DataEC50:  10nMAssay Description:Inhibition of mouse Pyk2 in MC3TC3 cells assessed as increase in alkaline phosphatase levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetProtein-tyrosine kinase 2-beta(Mouse)
Amgen

Curated by ChEMBL
LigandPNGBDBM50301356(N-(5-(6,7-dimethoxyquinolin-4-yloxy)pyridin-2-yl)-...)
Affinity DataEC50:  10nMAssay Description:Inhibition of mouse Pyk2 in MC3TC3 cells assessed as increase in osteocalcin levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetProtein-tyrosine kinase 2-beta(Mouse)
Amgen

Curated by ChEMBL
LigandPNGBDBM50402999(CHEMBL2207441)
Affinity DataIC50: 62nMAssay Description:Inhibition of PYK2 in mouse NIH-3T3 cells by LI-COR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProtein-tyrosine kinase 2-beta(Mouse)
Amgen

Curated by ChEMBL
LigandPNGBDBM50402996(CHEMBL2207440)
Affinity DataIC50: 98nMAssay Description:Inhibition of PYK2 in mouse NIH-3T3 cells by LI-COR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProtein-tyrosine kinase 2-beta(Mouse)
Amgen

Curated by ChEMBL
LigandPNGBDBM378885(US10266537, Compound 93)
Affinity DataIC50: 116nMAssay Description:The aim of this experiment is to detect the inhibitory activity of the compounds of the present invention against in vitro protein kinases using isot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2020
Entry Details
Go to US Patent

TargetProtein-tyrosine kinase 2-beta(Mouse)
Amgen

Curated by ChEMBL
LigandPNGBDBM50318872(1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(3-((...)
Affinity DataIC50: 190nMAssay Description:Inhibition of PYK2 in mouse NIH-3T3 cells by LI-COR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProtein-tyrosine kinase 2-beta(Mouse)
Amgen

Curated by ChEMBL
LigandPNGBDBM50403004(CHEMBL2207439)
Affinity DataIC50: 236nMAssay Description:Inhibition of PYK2 in mouse NIH-3T3 cells by LI-COR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProtein-tyrosine kinase 2-beta(Mouse)
Amgen

Curated by ChEMBL
LigandPNGBDBM50403003(CHEMBL2207823)
Affinity DataIC50: 265nMAssay Description:Inhibition of PYK2 in mouse NIH-3T3 cells by LI-COR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProtein-tyrosine kinase 2-beta(Mouse)
Amgen

Curated by ChEMBL
LigandPNGBDBM50403002(CHEMBL2207430)
Affinity DataIC50: 283nMAssay Description:Inhibition of PYK2 in mouse NIH-3T3 cells by LI-COR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProtein-tyrosine kinase 2-beta(Mouse)
Amgen

Curated by ChEMBL
LigandPNGBDBM50403001(CHEMBL2207438)
Affinity DataIC50: 328nMAssay Description:Inhibition of PYK2 in mouse NIH-3T3 cells by LI-COR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProtein-tyrosine kinase 2-beta(Mouse)
Amgen

Curated by ChEMBL
LigandPNGBDBM50402998(CHEMBL2207433)
Affinity DataIC50: 524nMAssay Description:Inhibition of PYK2 in mouse NIH-3T3 cells by LI-COR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProtein-tyrosine kinase 2-beta(Mouse)
Amgen

Curated by ChEMBL
LigandPNGBDBM50402990(CHEMBL2207427)
Affinity DataIC50: 530nMAssay Description:Inhibition of PYK2 in mouse NIH-3T3 cells by LI-COR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProtein-tyrosine kinase 2-beta(Mouse)
Amgen

Curated by ChEMBL
LigandPNGBDBM50402997(CHEMBL2207429)
Affinity DataIC50: 553nMAssay Description:Inhibition of PYK2 in mouse NIH-3T3 cells by LI-COR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProtein-tyrosine kinase 2-beta(Mouse)
Amgen

Curated by ChEMBL
LigandPNGBDBM50402993(CHEMBL2207432)
Affinity DataIC50: 607nMAssay Description:Inhibition of PYK2 in mouse NIH-3T3 cells by LI-COR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProtein-tyrosine kinase 2-beta(Mouse)
Amgen

Curated by ChEMBL
LigandPNGBDBM50403000(CHEMBL2207437)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of PYK2 in mouse NIH-3T3 cells by LI-COR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProtein-tyrosine kinase 2-beta(Mouse)
Amgen

Curated by ChEMBL
LigandPNGBDBM50402994(CHEMBL2207426)
Affinity DataIC50: 2.78E+3nMAssay Description:Inhibition of PYK2 in mouse NIH-3T3 cells by LI-COR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProtein-tyrosine kinase 2-beta(Mouse)
Amgen

Curated by ChEMBL
LigandPNGBDBM50402995(CHEMBL2207436)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of PYK2 in mouse NIH-3T3 cells by LI-COR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProtein-tyrosine kinase 2-beta(Mouse)
Amgen

Curated by ChEMBL
LigandPNGBDBM50403007(CHEMBL2207435)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of PYK2 in mouse NIH-3T3 cells by LI-COR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProtein-tyrosine kinase 2-beta(Mouse)
Amgen

Curated by ChEMBL
LigandPNGBDBM50402991(CHEMBL2207428)
Affinity DataIC50: 7.66E+3nMAssay Description:Inhibition of PYK2 in mouse NIH-3T3 cells by LI-COR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed