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Report error Found 8 of affinity data for UniProtKB/TrEMBL: Q9NRX4
Target14 kDa phosphohistidine phosphatase(Human)
University of Utah College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50442875(NORSTICTIC ACID)
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of PHPT1 (unknown origin) using DiFMUP as fluorogenic substrate incubated for 30 mins followed by substrate addition and measured every 60...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
Target14 kDa phosphohistidine phosphatase(Human)
University of Utah College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50186231([2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]ace...)
Affinity DataIC50: 1.83E+4nMAssay Description:Inhibition of human PHPT1 expressed in Escherichia coli BL21 (DE3) using pNPP as substrate incubated for 1 hr by multimode microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
Target14 kDa phosphohistidine phosphatase(Human)
University of Utah College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50056922(cid_73677 | CHEMBL173530 | 1,4-Dihydroxy-10-methox...)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of PHPT1 (unknown origin) using DiFMUP as fluorogenic substrate incubated for 30 mins followed by substrate addition and measured every 60...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
Target14 kDa phosphohistidine phosphatase(Human)
University of Utah College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50239376(ROXARSONE | CHEBI:35817)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of PHPT1 (unknown origin) using DiFMUP as fluorogenic substrate incubated for 30 mins followed by substrate addition and measured every 60...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
Target14 kDa phosphohistidine phosphatase(Human)
University of Utah College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50240028(Acetarsol | Acetarsone | Gynoplix | S.V.C. | Stova...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PHPT1 (unknown origin) using DiFMUP as fluorogenic substrate incubated for 30 mins followed by substrate addition and measured every 60...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
Target14 kDa phosphohistidine phosphatase(Human)
University of Utah College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50442875(NORSTICTIC ACID)
Affinity DataKi:  9.00E+4nMAssay Description:Inhibition of PHPT1 (unknown origin) assessed as inhibition constant measured up to 100 uM incubated up to 30 mins using DiFMUP as fluorogenic substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
Target14 kDa phosphohistidine phosphatase(Human)
University of Utah College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50186231([2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]ace...)
Affinity DataKi:  1.83E+5nMAssay Description:Inhibition of human PHPT1 expressed in Escherichia coli BL21 (DE3) using pNPP as substrate assessed as inhibition constant by reciprocal analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
Target14 kDa phosphohistidine phosphatase(Human)
University of Utah College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50220832(CHEMBL8211 | N-ethylmaleimide)
Affinity DataKi:  2.09E+5nMAssay Description:Inhibition of human PHPT1 expressed in Escherichia coli BL21 (DE3) using pNPP as substrate assessed as inhibition constant by reciprocal analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed