Compile Data Set for Download or QSAR
Report error Found 65 of affinity data for UniProtKB/TrEMBL: Q9NRW4
TargetDual specificity protein phosphatase 22(Human)
Ceptyr

Curated by ChEMBL
LigandPNGBDBM50168874(3-{5-[1-(4-Fluoro-phenyl)-meth-(Z)-ylidene]-4-oxo-...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of JNK-stimulating phosphatase-1 (JSP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 22(Human)
Ceptyr

Curated by ChEMBL
LigandPNGBDBM50425807(CHEMBL2316902)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of VHX (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 22(Human)
Ceptyr

Curated by ChEMBL
LigandPNGBDBM50425806(CHEMBL2316907)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of VHX (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 22(Human)
Ceptyr

Curated by ChEMBL
LigandPNGBDBM50556732(CHEMBL4750435)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of DUSP22 (unknown origin) pre-incubated for 20 mins followed by fluorescence substrate addition and measured after 120 mins by DiFMUP ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 22(Human)
Ceptyr

Curated by ChEMBL
LigandPNGBDBM50205422(N3-cyclohexyl-N1-(2,3-di(furan-2-yl)quinoxalin-6-y...)
Affinity DataIC50: 2.25E+3nMAssay Description:Inhibition of GST-tagged human recombinant JSP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 22(Human)
Ceptyr

Curated by ChEMBL
LigandPNGBDBM50205419(N3-butyl-N1-(2,3-di(furan-2-yl)quinoxalin-6-yl)-N3...)
Affinity DataIC50: 2.35E+3nMAssay Description:Inhibition of GST-tagged human recombinant JSP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 22(Human)
Ceptyr

Curated by ChEMBL
LigandPNGBDBM50205439(N1-(2,3-di(furan-2-yl)quinoxalin-6-yl)-N3,N3-dipro...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of GST-tagged human recombinant JSP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 22(Human)
Ceptyr

Curated by ChEMBL
LigandPNGBDBM50168885(3-{5-[1-(4-Nitro-phenyl)-meth-(Z)-ylidene]-4-oxo-2...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of JNK-stimulating phosphatase-1 (JSP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 22(Human)
Ceptyr

Curated by ChEMBL
LigandPNGBDBM50205438(N3-butyl-N1-(2,3-di(furan-2-yl)quinoxalin-6-yl)pip...)
Affinity DataIC50: 2.79E+3nMAssay Description:Inhibition of GST-tagged human recombinant JSP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 22(Human)
Ceptyr

Curated by ChEMBL
LigandPNGBDBM50425808(CHEMBL2316906)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of VHX (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 22(Human)
Ceptyr

Curated by ChEMBL
LigandPNGBDBM50205426(N3-cyclopentyl-N1-(2,3-di(furan-2-yl)quinoxalin-6-...)
Affinity DataIC50: 3.02E+3nMAssay Description:Inhibition of GST-tagged human recombinant JSP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 22(Human)
Ceptyr

Curated by ChEMBL
LigandPNGBDBM50168896(4-{5-[1-(4-Fluoro-phenyl)-meth-(Z)-ylidene]-4-oxo-...)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of JNK-stimulating phosphatase-1 (JSP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 22(Human)
Ceptyr

Curated by ChEMBL
LigandPNGBDBM50205428(N3-butyl-N1-(2,3-di(furan-2-yl)quinoxalin-6-yl)-N3...)
Affinity DataIC50: 5.55E+3nMAssay Description:Inhibition of GST-tagged human recombinant JSP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 22(Human)
Ceptyr

Curated by ChEMBL
LigandPNGBDBM50168876(3-{4-Oxo-5-[1-phenyl-meth-(Z)-ylidene]-2-thioxo-th...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of JNK-stimulating phosphatase-1 (JSP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 22(Human)
Ceptyr

Curated by ChEMBL
LigandPNGBDBM50168876(3-{4-Oxo-5-[1-phenyl-meth-(Z)-ylidene]-2-thioxo-th...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of JNK-stimulating phosphatase-1 (JSP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 22(Human)
Ceptyr

Curated by ChEMBL
LigandPNGBDBM50168893(3-{5-[1-Cyclohexyl-meth-(Z)-ylidene]-4-oxo-2-thiox...)
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of JNK-stimulating phosphatase-1 (JSP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 22(Human)
Ceptyr

Curated by ChEMBL
LigandPNGBDBM50205429(N3-tert-butyl-N1-(2,3-di(furan-2-yl)quinoxalin-6-y...)
Affinity DataIC50: 8.05E+3nMAssay Description:Inhibition of GST-tagged human recombinant JSP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 22(Human)
Ceptyr

Curated by ChEMBL
LigandPNGBDBM50205427(N1-(2,3-di(furan-2-yl)quinoxalin-6-yl)-N3-isobutyl...)
Affinity DataIC50: 8.36E+3nMAssay Description:Inhibition of GST-tagged human recombinant JSP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 22(Human)
Ceptyr

Curated by ChEMBL
LigandPNGBDBM50205432(N-(2,3-di(furan-2-yl)quinoxalin-6-yl)-3-(piperidin...)
Affinity DataIC50: 8.39E+3nMAssay Description:Inhibition of GST-tagged human recombinant JSP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 22(Human)
Ceptyr

Curated by ChEMBL
LigandPNGBDBM50168894((4-{4-Oxo-5-[1-phenyl-meth-(Z)-ylidene]-2-thioxo-t...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JNK-stimulating phosphatase-1 (JSP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 22(Human)
Ceptyr

Curated by ChEMBL
LigandPNGBDBM231167(US9340574, 7)
Affinity DataIC50: 1.00E+4nMpH: 7.0Assay Description:PTP activity was assayed using p-nitrophenyl phosphate (pNPP) as a substrate in 3,3-dimethylglutarate buffer (50 mM 3,3-dimethylglutarate, pH 7.0, 1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
Go to US Patent

TargetDual specificity protein phosphatase 22(Human)
Ceptyr

Curated by ChEMBL
LigandPNGBDBM50168886(4-{4-Oxo-5-[1-phenyl-meth-(Z)-ylidene]-2-thioxo-th...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of JNK-stimulating phosphatase-1 (JSP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 22(Human)
Ceptyr

Curated by ChEMBL
LigandPNGBDBM50205425(CHEMBL230842 | cid_2925555 | N1-(2,3-di(furan-2-yl...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of GST-tagged human recombinant JSP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 22(Human)
Ceptyr

Curated by ChEMBL
LigandPNGBDBM50168882(2-Hydroxy-4-{4-oxo-5-[1-phenyl-meth-(Z)-ylidene]-2...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of JNK-stimulating phosphatase-1 (JSP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 22(Human)
Ceptyr

Curated by ChEMBL
LigandPNGBDBM50168877(2-Hydroxy-5-{4-oxo-5-[1-phenyl-meth-(Z)-ylidene]-2...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of JNK-stimulating phosphatase-1 (JSP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 22(Human)
Ceptyr

Curated by ChEMBL
LigandPNGBDBM50168875(3-{4-Oxo-2-thioxo-5-[1-p-tolyl-meth-(Z)-ylidene]-t...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of JNK-stimulating phosphatase-1 (JSP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 22(Human)
Ceptyr

Curated by ChEMBL
LigandPNGBDBM50168881(4-{4-Oxo-5-[1-phenyl-meth-(Z)-ylidene]-2-thioxo-th...)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of JNK-stimulating phosphatase-1 (JSP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 22(Human)
Ceptyr

Curated by ChEMBL
LigandPNGBDBM50168883((4-{4-Oxo-5-[1-phenyl-meth-(Z)-ylidene]-2-thioxo-t...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of JNK-stimulating phosphatase-1 (JSP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 22(Human)
Ceptyr

Curated by ChEMBL
LigandPNGBDBM50168878((3-{4-Oxo-5-[1-phenyl-meth-(Z)-ylidene]-2-thioxo-t...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of JNK-stimulating phosphatase-1 (JSP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 22(Human)
Ceptyr

Curated by ChEMBL
LigandPNGBDBM82577(N-(4-fluoro-1,3-benzothiazol-2-yl)-5-(4-methoxyphe...)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of recombinant VHX (unknown origin) using OMFP as substrate after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 22(Human)
Ceptyr

Curated by ChEMBL
LigandPNGBDBM50168897(3-{5-[1-(4-Methoxy-phenyl)-meth-(Z)-ylidene]-4-oxo...)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of JNK-stimulating phosphatase-1 (JSP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 22(Human)
Ceptyr

Curated by ChEMBL
LigandPNGBDBM50205437(N1-(2,3-bis(4-fluorophenyl)quinoxalin-6-yl)-N3,N3-...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of GST-tagged human recombinant JSP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 22(Human)
Ceptyr

Curated by ChEMBL
LigandPNGBDBM50205434(N1-(2,3-dip-tolylquinoxalin-6-yl)-N3,N3-diethylpip...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of GST-tagged human recombinant JSP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 22(Human)
Ceptyr

Curated by ChEMBL
LigandPNGBDBM50205431(N1-(2,3-diphenylquinoxalin-6-yl)-N3,N3-diethylpipe...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of GST-tagged human recombinant JSP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 22(Human)
Ceptyr

Curated by ChEMBL
LigandPNGBDBM50205430(N1-(2,3-bis(4-bromophenyl)quinoxalin-6-yl)-N3,N3-d...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of GST-tagged human recombinant JSP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 22(Human)
Ceptyr

Curated by ChEMBL
LigandPNGBDBM50205435(N-(2,3-diphenylquinoxalin-6-yl)-3-(piperidine-1-ca...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of GST-tagged human recombinant JSP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 22(Human)
Ceptyr

Curated by ChEMBL
LigandPNGBDBM50205433(N1-(2,3-di(furan-2-yl)quinoxalin-6-yl)-N3-isopropy...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of GST-tagged human recombinant JSP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 22(Human)
Ceptyr

Curated by ChEMBL
LigandPNGBDBM50205424(N1-(2,3-bis(4-fluorophenyl)quinoxalin-6-yl)-N3-cyc...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of GST-tagged human recombinant JSP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 22(Human)
Ceptyr

Curated by ChEMBL
LigandPNGBDBM50205423(N3-cyclopentyl-N1-(2,3-dip-tolylquinoxalin-6-yl)pi...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of GST-tagged human recombinant JSP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 22(Human)
Ceptyr

Curated by ChEMBL
LigandPNGBDBM50205421(N1-(2,3-di(furan-2-yl)quinoxalin-6-yl)-N3-ethylpip...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of GST-tagged human recombinant JSP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 22(Human)
Ceptyr

Curated by ChEMBL
LigandPNGBDBM50205440(N1-(2,3-di(furan-2-yl)quinoxalin-6-yl)-N3,N3-dimet...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of GST-tagged human recombinant JSP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 22(Human)
Ceptyr

Curated by ChEMBL
LigandPNGBDBM50205436(N-(2,3-bis(4-bromophenyl)quinoxalin-6-yl)-3-(pyrro...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of GST-tagged human recombinant JSP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 22(Human)
Ceptyr

Curated by ChEMBL
LigandPNGBDBM84581(Thioxothiazolidinone derivative, 1)
Affinity DataIC50: 5.00E+4nMpH: 6.0 T: 2°CAssay Description:PTP assay were conducted at 25 C in 96-well plates. Reaction rates were determined using a Variokan plate reader from Thermo Electron. For assay pH...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2012
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 22(Human)
Ceptyr

Curated by ChEMBL
LigandPNGBDBM50168873(3-[4-Oxo-5-prop-(Z)-ylidene-2-thioxo-thiazolidin-3...)
Affinity DataIC50: 5.90E+4nMAssay Description:Inhibition of JNK-stimulating phosphatase-1 (JSP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 22(Human)
Ceptyr

Curated by ChEMBL
LigandPNGBDBM50168887(4-{4-Oxo-5-[1-phenyl-meth-(Z)-ylidene]-2-thioxo-th...)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of JNK-stimulating phosphatase-1 (JSP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 22(Human)
Ceptyr

Curated by ChEMBL
LigandPNGBDBM50168889(3-Methyl-4-{4-oxo-5-[1-phenyl-meth-(Z)-ylidene]-2-...)
Affinity DataIC50: 6.60E+4nMAssay Description:Inhibition of JNK-stimulating phosphatase-1 (JSP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 22(Human)
Ceptyr

Curated by ChEMBL
LigandPNGBDBM50262987(Illudalic acid | CHEMBL506661)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of LMWPTP (unknown origin) using DiFMUP as substrate incubated for 30 mins followed by substrate addition at pH 6.5 by standard phosphatas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 22(Human)
Ceptyr

Curated by ChEMBL
LigandPNGBDBM50348092(CHEMBL1800273)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of VHXMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 22(Human)
Ceptyr

Curated by ChEMBL
LigandPNGBDBM50263036(3-Hydroxy-6-methoxy-8,8-dimethyl-1-oxo-1,3,4,7,8,9...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of LMWPTP (unknown origin) using DiFMUP as substrate incubated for 30 mins followed by substrate addition at pH 6.5 by standard phosphatas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 22(Human)
Ceptyr

Curated by ChEMBL
LigandPNGBDBM50205441(N3-cyclohexyl-N1-(2,3-dimethoxyquinoxalin-6-yl)pip...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GST-tagged human recombinant JSP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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