Compile Data Set for Download or QSAR
Report error Found 2 of affinity data for UniProtKB/TrEMBL: Q9NPP4
TargetNLR family CARD domain-containing protein 4(Human)
Jecure Therapeutics

Curated by ChEMBL
LigandPNGBDBM50607509(CHEMBL5219789)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of NLRC4 inflammasome activation in LPS/flagellin-treated human THP-1 cells preincubated with LPS for 3 hrs followed by compound addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetNLR family CARD domain-containing protein 4(Human)
Jecure Therapeutics

Curated by ChEMBL
LigandPNGBDBM640460(US20230399319, Example 2-004)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of NLRC4 (unknown origin) in PMA-differentiated human THP-1 cells assessed as inhibition of IL-1 beta production pretreated for 15 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed