Compile Data Set for Download or QSAR
Report error Found 4 of affinity data for UniProtKB/TrEMBL: Q9N1U3
TargetGlucocorticoid receptor(Pig)
Oric Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM18627(Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...)
Affinity DataIC50: 11nMAssay Description:Antagonist activity at GR in mini pig PBMC assessed as reduction in dexamethasone-induced GILZ gene expression incubated for 24 hrs by RT-qPCR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Pig)
Oric Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM18627(Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...)
Affinity DataIC50: 20nMAssay Description:Antagonist activity at GR in mini pig PBMC assessed as reduction in dexamethasone-induced FKBP5 gene expression incubated for 24 hrs by RT-qPCR metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Pig)
Oric Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50368933(CHEMBL4161754)
Affinity DataIC50: 39nMAssay Description:Antagonist activity at GR in mini pig PBMC assessed as reduction in dexamethasone-induced FKBP5 gene expression incubated for 24 hrs by RT-qPCR metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Pig)
Oric Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50368933(CHEMBL4161754)
Affinity DataIC50: 181nMAssay Description:Antagonist activity at GR in mini pig PBMC assessed as reduction in dexamethasone-induced GILZ gene expression incubated for 24 hrs by RT-qPCR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed