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TargetVitamin K epoxide reductase complex subunit 1(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50535485(CHEMBL4594145)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of VKOR (unknown origin) in HEK293 expressing FIXgla-PC incubated for 48 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetVitamin K epoxide reductase complex subunit 1(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50343352(2-hydroxy-3-(3-oxo-1-phenylbutyl)-4H-chromen-4-one...)
Affinity DataIC50: 8.80nMAssay Description:Inhibition of VKOR (unknown origin) in HEK293 expressing FIXgla-PC incubated for 48 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetVitamin K epoxide reductase complex subunit 1(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50535487(CHEMBL4530669)
Affinity DataIC50: 58nMAssay Description:Inhibition of VKOR (unknown origin) in HEK293 expressing FIXgla-PC incubated for 48 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetVitamin K epoxide reductase complex subunit 1(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50535484(CHEMBL4517532)
Affinity DataIC50: 59nMAssay Description:Inhibition of VKOR (unknown origin) in HEK293 expressing FIXgla-PC incubated for 48 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetVitamin K epoxide reductase complex subunit 1(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50535488(CHEMBL4443961)
Affinity DataIC50: 90nMAssay Description:Inhibition of VKOR (unknown origin) in HEK293 expressing FIXgla-PC incubated for 48 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetVitamin K epoxide reductase complex subunit 1(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50629252(CHEMBL5435296)
Affinity DataIC50: 98nMAssay Description:Inhibition of recombinant human wild-type VKORC1 expressed in Pichia pastoris membrane incubated for 30 mins in presence of presence of dithiothreito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetVitamin K epoxide reductase complex subunit 1(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50629253(CHEBI:81892 | Brodifacoum | BRODIFACOUM)
Affinity DataIC50: 150nMAssay Description:Inhibition of recombinant human wild-type VKORC1 expressed in Pichia pastoris membrane incubated for 30 mins in presence of presence of dithiothreito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetVitamin K epoxide reductase complex subunit 1(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50629247(CHEMBL5436380)
Affinity DataIC50: 498nMAssay Description:Inhibition of recombinant human wild-type VKORC1 expressed in Pichia pastoris membrane incubated for 30 mins in presence of presence of dithiothreito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetVitamin K epoxide reductase complex subunit 1(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50629246(CHEMBL5433796)
Affinity DataIC50: 527nMAssay Description:Inhibition of recombinant human wild-type VKORC1 expressed in Pichia pastoris membrane incubated for 30 mins in presence of presence of dithiothreito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetVitamin K epoxide reductase complex subunit 1(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50629245(CHEMBL5432023)
Affinity DataIC50: 643nMAssay Description:Inhibition of recombinant human wild-type VKORC1 expressed in Pichia pastoris membrane incubated for 30 mins in presence of presence of dithiothreito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetVitamin K epoxide reductase complex subunit 1(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50629250(CHEMBL5403819)
Affinity DataIC50: 873nMAssay Description:Inhibition of recombinant human wild-type VKORC1 expressed in Pichia pastoris membrane incubated for 30 mins in presence of presence of dithiothreito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetVitamin K epoxide reductase complex subunit 1(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50343352(2-hydroxy-3-(3-oxo-1-phenylbutyl)-4H-chromen-4-one...)
Affinity DataIC50: 1.06E+3nMAssay Description:Inhibition of recombinant human wild-type VKORC1 expressed in Pichia pastoris membrane incubated for 30 mins in presence of presence of dithiothreito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetVitamin K epoxide reductase complex subunit 1(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50629244(CHEMBL5404461)
Affinity DataIC50: 1.53E+3nMAssay Description:Inhibition of recombinant human wild-type VKORC1 expressed in Pichia pastoris membrane incubated for 30 mins in presence of presence of dithiothreito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetVitamin K epoxide reductase complex subunit 1(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50535486(CHEMBL4463800)
Affinity DataIC50: 1.93E+3nMAssay Description:Inhibition of VKOR (unknown origin) in HEK293 expressing FIXgla-PC incubated for 48 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetVitamin K epoxide reductase complex subunit 1(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50629248(CHEMBL5434421)
Affinity DataIC50: 2.72E+3nMAssay Description:Inhibition of recombinant human wild-type VKORC1 expressed in Pichia pastoris membrane incubated for 30 mins in presence of presence of dithiothreito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetVitamin K epoxide reductase complex subunit 1(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50629249(CHEMBL5396437)
Affinity DataIC50: 5.54E+3nMAssay Description:Inhibition of recombinant human wild-type VKORC1 expressed in Pichia pastoris membrane incubated for 30 mins in presence of presence of dithiothreito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetVitamin K epoxide reductase complex subunit 1(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50629254(Warfarin alcohol | WARFARIN ALCOHOL)
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibition of recombinant human wild-type VKORC1 expressed in Pichia pastoris membrane incubated for 30 mins in presence of presence of dithiothreito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetVitamin K epoxide reductase complex subunit 1(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50629251(CHEMBL5424000)
Affinity DataIC50: 2.39E+4nMAssay Description:Inhibition of recombinant human wild-type VKORC1 expressed in Pichia pastoris membrane incubated for 30 mins in presence of presence of dithiothreito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetVitamin K epoxide reductase complex subunit 1(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50629255(Isoprenylcoumarin | ISOPRENYLCOUMARIN)
Affinity DataIC50: 7.90E+4nMAssay Description:Inhibition of recombinant human wild-type VKORC1 expressed in Pichia pastoris membrane incubated for 30 mins in presence of presence of dithiothreito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetVitamin K epoxide reductase complex subunit 1(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50343352(2-hydroxy-3-(3-oxo-1-phenylbutyl)-4H-chromen-4-one...)
Affinity DataKi:  1.80E+3nM ΔG°:  -34.1kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, standard reactions were performed in 200 mM Hepes buffer, pH 7.4, containing 150 mM KCl, 1 mM dithiothreitol, 0.25 to 2 g liter-1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/14/2017
Entry Details Article
PubMed
TargetVitamin K epoxide reductase complex subunit 1(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50386849(CHEMBL2048091)
Affinity DataKi:  4.48E+4nMAssay Description:Inhibition of VKORC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetVitamin K epoxide reductase complex subunit 1(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50386852(CHEMBL2048084)
Affinity DataKi:  6.89E+4nMAssay Description:Inhibition of VKORC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetVitamin K epoxide reductase complex subunit 1(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50386850(CHEMBL2048092)
Affinity DataKi:  7.42E+4nMAssay Description:Inhibition of VKORC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetVitamin K epoxide reductase complex subunit 1(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50386851(CHEMBL2048096)
Affinity DataKi:  7.96E+4nMAssay Description:Inhibition of VKORC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed