Compile Data Set for Download or QSAR
Report error Found 15 of affinity data for UniProtKB/TrEMBL: Q99028
TargetCatechol O-methyltransferase(Pig)
Instituto De QuíMica OrgáNica General (Csic)

Curated by ChEMBL
LigandPNGBDBM50004045(CHEMBL357072 | 2,3-Dihydroxy-4-nitro-benzaldehyde)
Affinity DataIC50: 1.50E+3nMAssay Description:In vitro inhibition of Catechol-O-methyltransferase (COMT) from isolated partially purified pig liver enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCatechol O-methyltransferase(Pig)
Instituto De QuíMica OrgáNica General (Csic)

Curated by ChEMBL
LigandPNGBDBM50004049(CHEMBL139882 | 3,4-Dihydroxy-2-nitro-benzaldehyde)
Affinity DataIC50: 1.50E+3nMAssay Description:In vitro inhibition of Catechol-O-methyltransferase (COMT) from isolated partially purified pig liver enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCatechol O-methyltransferase(Pig)
Instituto De QuíMica OrgáNica General (Csic)

Curated by ChEMBL
LigandPNGBDBM50004043(3,4-Dihydroxy-5-nitro-benzaldehyde | CHEMBL1244 | ...)
Affinity DataIC50: 2.00E+3nMAssay Description:In vitro inhibition of Catechol-O-methyltransferase (COMT) from isolated partially purified pig liver enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCatechol O-methyltransferase(Pig)
Instituto De QuíMica OrgáNica General (Csic)

Curated by ChEMBL
LigandPNGBDBM50004047(CHEMBL141858 | 2,3-Dihydroxy-5-nitro-benzaldehyde)
Affinity DataIC50: 2.10E+3nMAssay Description:In vitro inhibition of Catechol-O-methyltransferase (COMT) from isolated partially purified pig liver enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCatechol O-methyltransferase(Pig)
Instituto De QuíMica OrgáNica General (Csic)

Curated by ChEMBL
LigandPNGBDBM50004048(CHEMBL142876 | 4,5-Dihydroxy-2-nitro-benzaldehyde)
Affinity DataIC50: 8.50E+3nMAssay Description:In vitro inhibition of Catechol-O-methyltransferase (COMT) from isolated partially purified pig liver enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCatechol O-methyltransferase(Pig)
Instituto De QuíMica OrgáNica General (Csic)

Curated by ChEMBL
LigandPNGBDBM50004046(CHEMBL334706 | 2,3-Dihydroxy-6-nitro-benzaldehyde)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibition of Catechol-O-methyltransferase (COMT) from isolated partially purified pig liver enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCatechol O-methyltransferase(Pig)
Instituto De QuíMica OrgáNica General (Csic)

Curated by ChEMBL
LigandPNGBDBM50004044(CHEMBL89320 | 3-Hydroxy-4-methoxy-5-nitro-benzalde...)
Affinity DataIC50: 3.40E+4nMAssay Description:In vitro inhibition of Catechol-O-methyltransferase (COMT) from isolated partially purified pig liver enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCatechol O-methyltransferase(Pig)
Instituto De QuíMica OrgáNica General (Csic)

Curated by ChEMBL
LigandPNGBDBM50058814(N,N'-1,3-Propanediylbis(3,4-dihydroxybenzamide) | ...)
Affinity DataKi:  300nMAssay Description:In vitro inhibitory activity against Catechol-O-methyltransferase from porcine liver; Competitive mode of inhibitionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCatechol O-methyltransferase(Pig)
Instituto De QuíMica OrgáNica General (Csic)

Curated by ChEMBL
LigandPNGBDBM50058813(3,4,5-Trihydroxy-N-propyl-benzamide | CHEMBL64275)
Affinity DataKi:  500nMAssay Description:In vitro inhibitory activity against Catechol-O-methyltransferase from porcine liver; Competitive mode of inhibitionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCatechol O-methyltransferase(Pig)
Instituto De QuíMica OrgáNica General (Csic)

Curated by ChEMBL
LigandPNGBDBM50058812(N,N'-1,3-Propanediylbis(3,4,5-trihydroxybenzamide)...)
Affinity DataKi:  6.60E+3nMAssay Description:In vitro inhibitory activity against Catechol-O-methyltransferase from porcine liver; Uncompetitive mode of inhibitionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCatechol O-methyltransferase(Pig)
Instituto De QuíMica OrgáNica General (Csic)

Curated by ChEMBL
LigandPNGBDBM50004044(CHEMBL89320 | 3-Hydroxy-4-methoxy-5-nitro-benzalde...)
Affinity DataKi:  1.35E+4nMAssay Description:Compound was evaluated for reversible inhibition of Catechol O-methyltransferase with variable AdoMet and saturating catechol as substrate (mixed inh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCatechol O-methyltransferase(Pig)
Instituto De QuíMica OrgáNica General (Csic)

Curated by ChEMBL
LigandPNGBDBM50004044(CHEMBL89320 | 3-Hydroxy-4-methoxy-5-nitro-benzalde...)
Affinity DataKi:  1.72E+4nMAssay Description:Compound was evaluated for reversible inhibition of Catechol O-methyltransferase with saturating AdoMet and variable catechol as substrate (Non-compe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCatechol O-methyltransferase(Pig)
Instituto De QuíMica OrgáNica General (Csic)

Curated by ChEMBL
LigandPNGBDBM50058815(N,N'-1,5-Pentanediylbis(3,4,5-trihydroxybenzamide)...)
Affinity DataKi:  2.67E+4nMAssay Description:In vitro inhibitory activity against Catechol-O-methyltransferase from porcine liver; Uncompetitive mode of inhibitionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCatechol O-methyltransferase(Pig)
Instituto De QuíMica OrgáNica General (Csic)

Curated by ChEMBL
LigandPNGBDBM50058811(N,N'-1,6-Hexanediylbis(3,4,5-trihydroxybenzamide)H...)
Affinity DataKi:  3.50E+4nMAssay Description:In vitro inhibitory activity against Catechol-O-methyltransferase from porcine liver; Uncompetitive mode of inhibitionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCatechol O-methyltransferase(Pig)
Instituto De QuíMica OrgáNica General (Csic)

Curated by ChEMBL
LigandPNGBDBM50058816(N,N'-1,2-Ethanediylbis(3,4,5-trihydroxybenzamide)H...)
Affinity DataKi:  1.36E+5nMAssay Description:In vitro inhibitory activity against Catechol-O-methyltransferase from porcine liver; Uncompetitive mode of inhibitionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed