Compile Data Set for Download or QSAR
Report error Found 43 of affinity data for UniProtKB/TrEMBL: Q920R3
TargetAcyl-CoA (8-3)-desaturase(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50535222(CHEMBL4439992)
Affinity DataKd:  2.70nMAssay Description:Binding affinity to D5D in Sprague-Dawley rat liver microsomes after 150 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50245999(CHEMBL4084502)
Affinity DataIC50: 1nMAssay Description:Displacement of [3H]T-3364366 from D5D in rat liver microsomal membrane preincubated for 15 mins followed by radioligand addition measured after 150 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50245998(CHEMBL4064555)
Affinity DataIC50: 1.5nMAssay Description:Displacement of [3H]T-3364366 from D5D in rat liver microsomal membrane preincubated for 15 mins followed by radioligand addition measured after 150 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50535222(CHEMBL4439992)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of D5D in rat RLN10 cells using [14C]DGLA as substrate preincubated for 30 mins followed by substrate addition measured after 3 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50246049(CHEMBL4102458)
Affinity DataIC50: 4nMAssay Description:Displacement of [3H]T-3364366 from D5D in rat liver microsomal membrane preincubated for 15 mins followed by radioligand addition measured after 150 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50246000(CHEMBL4070383)
Affinity DataIC50: 5.30nMAssay Description:Displacement of [3H]T-3364366 from D5D in rat liver microsomal membrane preincubated for 15 mins followed by radioligand addition measured after 150 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50246000(CHEMBL4070383)
Affinity DataIC50: 5.30nMAssay Description:Displacement of [3H]T-3364366 from D5D in rat liver microsomal membrane preincubated for 15 mins followed by radioligand addition measured after 150 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50246023(CHEMBL4060775)
Affinity DataIC50: 8.5nMAssay Description:Displacement of [3H]T-3364366 from D5D in rat liver microsomal membrane preincubated for 15 mins followed by radioligand addition measured after 150 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50246076(CHEMBL4063561)
Affinity DataIC50: 12nMAssay Description:Displacement of [3H]T-3364366 from D5D in rat liver microsomal membrane preincubated for 15 mins followed by radioligand addition measured after 150 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50246045(CHEMBL4090490)
Affinity DataIC50: 13nMAssay Description:Displacement of [3H]T-3364366 from D5D in rat liver microsomal membrane preincubated for 15 mins followed by radioligand addition measured after 150 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50535222(CHEMBL4439992)
Affinity DataIC50: 19nMAssay Description:Inhibition of D5D in Sprague-Dawley rat liver microsomes using [14C]DGLA as substrate preincubated for 5 mins measured after 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50246007(CHEMBL4104260)
Affinity DataIC50: 23nMAssay Description:Displacement of [3H]T-3364366 from D5D in rat liver microsomal membrane preincubated for 15 mins followed by radioligand addition measured after 150 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50116708(CHEMBL2263368)
Affinity DataIC50: 26nMAssay Description:Inhibition of D5D in rat RLN10 cells using [14C]DGLA as substrate preincubated for 30 mins followed by substrate addition measured after 3 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50257967(N-(2-(7-(4-chloro-3-(trifluoromethyl)benzylamino)-...)
Affinity DataIC50: 30nMAssay Description:Inhibition of rat microsomal Delta-5-desaturaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50258014(N-(2-(2-(3,4-dichlorobenzylamino)-6-(4-methoxyphen...)
Affinity DataIC50: 30nMAssay Description:Inhibition of rat microsomal Delta-5-desaturaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50258197(N-(2-(6-(3,4-dichlorobenzylamino)-2-(4-methoxyphen...)
Affinity DataIC50: 30nMAssay Description:Inhibition of rat microsomal Delta-5-desaturaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50257757(3-(6-(3,4-dichlorobenzylamino)-2-(4-methoxyphenyl)...)
Affinity DataIC50: 30nMAssay Description:Inhibition of rat microsomal Delta-5-desaturaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50257860(N-(2-(7-(3,4-dichlorobenzylamino)-3-(4-methoxyphen...)
Affinity DataIC50: 30nMAssay Description:Inhibition of rat microsomal Delta-5-desaturaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50257808(N-(2-(6-(3,4-dichlorobenzylamino)-3-oxo-2-(pyridin...)
Affinity DataIC50: 30nMAssay Description:Inhibition of rat microsomal Delta-5-desaturaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50257758(3-(2-(4-methoxyphenyl)-3-oxo-6-(3-(trifluoromethyl...)
Affinity DataIC50: 30nMAssay Description:Inhibition of rat microsomal Delta-5-desaturaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50257919(N-(2-(7-(3,4-dichlorobenzylamino)-3-(4-methoxyphen...)
Affinity DataIC50: 30nMAssay Description:Inhibition of rat microsomal Delta-5-desaturaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50245997(CHEMBL4072166)
Affinity DataIC50: 39nMAssay Description:Displacement of [3H]T-3364366 from D5D in rat liver microsomal membrane preincubated for 15 mins followed by radioligand addition measured after 150 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50246047(CHEMBL4097127)
Affinity DataIC50: 47nMAssay Description:Displacement of [3H]T-3364366 from D5D in rat liver microsomal membrane preincubated for 15 mins followed by radioligand addition measured after 150 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50246065(CHEMBL4066595)
Affinity DataIC50: 49nMAssay Description:Displacement of [3H]T-3364366 from D5D in rat liver microsomal membrane preincubated for 15 mins followed by radioligand addition measured after 150 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50246022(CHEMBL4080025)
Affinity DataIC50: 51nMAssay Description:Displacement of [3H]T-3364366 from D5D in rat liver microsomal membrane preincubated for 15 mins followed by radioligand addition measured after 150 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50246006(CHEMBL4087912)
Affinity DataIC50: 78nMAssay Description:Displacement of [3H]T-3364366 from D5D in rat liver microsomal membrane preincubated for 15 mins followed by radioligand addition measured after 150 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50246046(CHEMBL4069465)
Affinity DataIC50: 79nMAssay Description:Displacement of [3H]T-3364366 from D5D in rat liver microsomal membrane preincubated for 15 mins followed by radioligand addition measured after 150 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50246066(CHEMBL4085437)
Affinity DataIC50: 150nMAssay Description:Displacement of [3H]T-3364366 from D5D in rat liver microsomal membrane preincubated for 15 mins followed by radioligand addition measured after 150 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50116708(CHEMBL2263368)
Affinity DataIC50: 160nMAssay Description:Inhibition of D5D in Sprague-Dawley rat liver microsomes using [14C]DGLA as substrate preincubated for 5 mins measured after 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50246048(CHEMBL4079106)
Affinity DataIC50: 310nMAssay Description:Displacement of [3H]T-3364366 from D5D in rat liver microsomal membrane preincubated for 15 mins followed by radioligand addition measured after 150 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50245996(CHEMBL4091399)
Affinity DataIC50: 360nMAssay Description:Displacement of [3H]T-3364366 from D5D in rat liver microsomal membrane preincubated for 15 mins followed by radioligand addition measured after 150 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50246063(CHEMBL4073142)
Affinity DataIC50: 410nMAssay Description:Displacement of [3H]T-3364366 from D5D in rat liver microsomal membrane preincubated for 15 mins followed by radioligand addition measured after 150 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50246064(CHEMBL4062788)
Affinity DataIC50: 450nMAssay Description:Displacement of [3H]T-3364366 from D5D in rat liver microsomal membrane preincubated for 15 mins followed by radioligand addition measured after 150 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50329966(2-(2'-fluorobiphenyl-4-yl)-6-(methylsulfonyl)-1H-b...)
Affinity DataIC50: 5.17E+3nMAssay Description:Inhibition of Delta(5) fatty acid desaturase in freshly isolated rat hepatocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50246057(CHEMBL4069792)
Affinity DataIC50: 5.80E+3nMAssay Description:Displacement of [3H]T-3364366 from D5D in rat liver microsomal membrane preincubated for 15 mins followed by radioligand addition measured after 150 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50246077(CHEMBL4084463)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]T-3364366 from D5D in rat liver microsomal membrane preincubated for 15 mins followed by radioligand addition measured after 150 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50298898(2-hydroxy-N-(2-(3-methyl-2-oxo-7-(3-(trifluorometh...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of stearoyl-CoA delta5 desaturase in rat microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50329966(2-(2'-fluorobiphenyl-4-yl)-6-(methylsulfonyl)-1H-b...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of rat Delta(5) fatty acid desaturase by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50393164(CHEMBL2153599)
Affinity DataIC50: 1.00E+8nMAssay Description:Inhibition of rat delta-5 desaturase activity expressed in human HEpG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50393165(CHEMBL2153600)
Affinity DataIC50: 1.00E+8nMAssay Description:Inhibition of rat delta-5 desaturase activity expressed in human HEpG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50393166(CHEMBL2153601)
Affinity DataIC50: 1.00E+8nMAssay Description:Inhibition of rat delta-5 desaturase activity expressed in human HEpG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50305768(2-methyl-5-(6-(4-(2-(trifluoromethyl)phenoxy)piper...)
Affinity DataIC50: 1.00E+8nMAssay Description:Inhibition of rat delta-5 desaturase activity expressed in human HEpG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAcyl-CoA (8-3)-desaturase(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50362592(CHEMBL1938870)
Affinity DataIC50: 1.00E+8nMAssay Description:Inhibition of rat delta-5 desaturase activity expressed in human HEpG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed