Compile Data Set for Download or QSAR
Report error Found 278 of affinity data for UniProtKB/TrEMBL: Q8WWI4
TargetHomeodomain-interacting protein kinase 2(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50460939BDBM50460939(CHEMBL4228654)
Affinity DataIC50: 3nMAssay Description:Inhibition of HIPK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 2(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563555BDBM50563555(CHEMBL4750420)
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant HIPK2 using myelin substrate by radiometric scintillation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 2(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 31085BDBM31085(cid_11409972 | 1-[4-[(4-ethylpiperazin-1-yl)methyl...)
Affinity DataKd:  7.30nMAssay Description:Binding constant for HIPK2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 2(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 81551BDBM81551(Furan thiazolidinediones, A64)
Affinity DataIC50: 74nM Kd:  9.5nMAssay Description:In vitro biochemical assays were performed in parallel to determine the most potent tool compound.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2011
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 2(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563556BDBM50563556(CHEMBL4743939)
Affinity DataIC50: 15nMAssay Description:Inhibition of human recombinant HIPK2 using myelin substrate by radiometric scintillation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 2(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50388783BDBM50388783(CHEMBL2062565)
Affinity DataIC50: 20nMAssay Description:Inhibition of HipK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 2(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563557BDBM50563557(CHEMBL4790791)
Affinity DataIC50: 28nMAssay Description:Inhibition of human recombinant HIPK2 using myelin substrate by radiometric scintillation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 2(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50560704BDBM50560704(CHEMBL4754195)
Affinity DataIC50: 29nMAssay Description:Inhibition of human HIPK2 by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 2(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50560704BDBM50560704(CHEMBL4754195)
Affinity DataIC50: 29nMAssay Description:Inhibition of human recombinant HIPK2 using myelin substrate by radiometric scintillation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 2(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563539BDBM50563539(CHEMBL4762964)
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant HIPK2 using myelin substrate by radiometric scintillation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 2(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50507430BDBM50507430(CHEMBL3937369)
Affinity DataIC50: 30nMAssay Description:Inhibition recombinant human HIPK2 (165 to 564 residues) after 5 mins in presence of [33P] ATP by Topcount methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 2(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50388786BDBM50388786(CHEMBL2062563)
Affinity DataIC50: 30nMAssay Description:Inhibition of HipK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 2(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 4814BDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKd:  31nMAssay Description:Binding affinity to HIPK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 2(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 4814BDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKd:  31nMAssay Description:Binding constant for HIPK2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 2(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50110183BDBM50110183(Abemaciclib | LY-2835219 | US10696678, Example LY2...)
Affinity DataIC50: 31nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged HIPK2 (165 to 564 residues) expressed in baculovirus infected Sf21 insect cells using MBP as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHomeodomain-interacting protein kinase 2(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50110183BDBM50110183(Abemaciclib | LY-2835219 | US10696678, Example LY2...)
Affinity DataIC50: 31nMAssay Description:Inhibition of HIPK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHomeodomain-interacting protein kinase 2(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50437434BDBM50437434(CHEMBL2409175)
Affinity DataIC50: 40nMAssay Description:Inhibition of Hipk-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 2(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50172243BDBM50172243(CHEMBL3103192)
Affinity DataIC50: 40nMAssay Description:Inhibition of Hipk2 (unknown origin) by quantitative PCRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2017
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 2(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563541BDBM50563541(CHEMBL4743730)
Affinity DataIC50: 41nMAssay Description:Inhibition of human recombinant HIPK2 using myelin substrate by radiometric scintillation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 2(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563554BDBM50563554(CHEMBL4790030)
Affinity DataIC50: 42nMAssay Description:Inhibition of human recombinant HIPK2 using myelin substrate by radiometric scintillation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 2(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50388782BDBM50388782(CHEMBL2062564)
Affinity DataIC50: 50nMAssay Description:Inhibition of HipK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 2(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50388784BDBM50388784(CHEMBL2062575)
Affinity DataIC50: 60nMAssay Description:Inhibition of HipK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 2(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563540BDBM50563540(CHEMBL4740998)
Affinity DataIC50: 68nMAssay Description:Inhibition of human recombinant HIPK2 using myelin substrate by radiometric scintillation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 2(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563538BDBM50563538(CHEMBL4797457)
Affinity DataIC50: 70nMAssay Description:Inhibition of human recombinant HIPK2 using myelin substrate by radiometric scintillation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 2(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563559BDBM50563559(CHEMBL4587433)
Affinity DataIC50: 74nMAssay Description:Inhibition of HIPK2 (unknown origin) by selectscreen kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 2(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 31095BDBM31095(5-[(Z)-(5-fluoranyl-2-oxidanylidene-1H-indol-3-yli...)
Affinity DataKd:  92nMAssay Description:Binding constant for HIPK2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 2 [1-640](Human)
Tongji University

US Patent
LigandChemical structure of BindingDB Monomer ID 809301BDBM809301((Z)-2-((1H-benzo[d]imidazol-6-yl)amino)-5-(benzo[d...)
Affinity DataIC50: 100nMAssay Description:Briefly, HIPK2 (1 nM) in the enzymatic buffer solutions (40 mM Tris, pH 7.5, 20 mM MgCl2, 0.1 mg/ml BSA, 50 μM DTT) were mixed with various concentra...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/19/2026
Entry Details
US Patent

TargetHomeodomain-interacting protein kinase 2 [1-640](Human)
Tongji University

US Patent
LigandChemical structure of BindingDB Monomer ID 809295BDBM809295(N-(1,3-benzothiazol-6-yl)-N-[(4Z)-4-[(1,3-benzothi...)
Affinity DataIC50: 100nMAssay Description:Briefly, HIPK2 (1 nM) in the enzymatic buffer solutions (40 mM Tris, pH 7.5, 20 mM MgCl2, 0.1 mg/ml BSA, 50 μM DTT) were mixed with various concentra...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/19/2026
Entry Details
US Patent

TargetHomeodomain-interacting protein kinase 2 [1-640](Human)
Tongji University

US Patent
LigandChemical structure of BindingDB Monomer ID 809285BDBM809285((Z)-5-(benzo[d]thiazol-6-ylmethylene)-2-((2,3-dihy...)
Affinity DataIC50: 100nMAssay Description:Briefly, HIPK2 (1 nM) in the enzymatic buffer solutions (40 mM Tris, pH 7.5, 20 mM MgCl2, 0.1 mg/ml BSA, 50 μM DTT) were mixed with various concentra...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/19/2026
Entry Details
US Patent

TargetHomeodomain-interacting protein kinase 2 [1-640](Human)
Tongji University

US Patent
LigandChemical structure of BindingDB Monomer ID 809258BDBM809258((Z)-2-(benzo[d]thiazol-6-ylamino)-5-(benzo[d]thiaz...)
Affinity DataIC50: 100nMAssay Description:Briefly, HIPK2 (1 nM) in the enzymatic buffer solutions (40 mM Tris, pH 7.5, 20 mM MgCl2, 0.1 mg/ml BSA, 50 μM DTT) were mixed with various concentra...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/19/2026
Entry Details
US Patent

TargetHomeodomain-interacting protein kinase 2 [1-640](Human)
Tongji University

US Patent
LigandChemical structure of BindingDB Monomer ID 809273BDBM809273((Z)-2-((1H-indol-5-yl)amino)-5-(benzo[d]thiazol-6-...)
Affinity DataIC50: 100nMAssay Description:Briefly, HIPK2 (1 nM) in the enzymatic buffer solutions (40 mM Tris, pH 7.5, 20 mM MgCl2, 0.1 mg/ml BSA, 50 μM DTT) were mixed with various concentra...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/19/2026
Entry Details
US Patent

TargetHomeodomain-interacting protein kinase 2 [1-640](Human)
Tongji University

US Patent
LigandChemical structure of BindingDB Monomer ID 809279BDBM809279((Z)-2-(benzo[d]thiazol-6-ylamino)-5-((1-methyl-1H-...)
Affinity DataIC50: 100nMAssay Description:Briefly, HIPK2 (1 nM) in the enzymatic buffer solutions (40 mM Tris, pH 7.5, 20 mM MgCl2, 0.1 mg/ml BSA, 50 μM DTT) were mixed with various concentra...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/19/2026
Entry Details
US Patent

TargetHomeodomain-interacting protein kinase 2(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399540BDBM50399540(FORETINIB | US10464902, Foretinib | US10882853, Co...)
Affinity DataIC50: 100nMAssay Description:Inhibition of HIPK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 2 [1-640](Human)
Tongji University

US Patent
LigandChemical structure of BindingDB Monomer ID 809294BDBM809294((Z)-5-(benzo[d]thiazol-6-ylmethylene)-2-((2-methyl...)
Affinity DataIC50: 100nMAssay Description:Briefly, HIPK2 (1 nM) in the enzymatic buffer solutions (40 mM Tris, pH 7.5, 20 mM MgCl2, 0.1 mg/ml BSA, 50 μM DTT) were mixed with various concentra...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/19/2026
Entry Details
US Patent

TargetHomeodomain-interacting protein kinase 2(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 17055BDBM17055((9S)-9-[(dimethylamino)methyl]-6,7,10,11-tetrahydr...)
Affinity DataIC50: 100nMAssay Description:Inhibition of HIPK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 2(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 16673BDBM16673(BAY439006 | CHEMBL1336 | BAY 43-9006 | 4-[4-({[4-c...)
Affinity DataIC50: 100nMAssay Description:Inhibition of HIPK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 2(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50242737BDBM50242737((R,Z)-5-(2,6-dichlorobenzylsulfonyl)-3-((3,5-dimet...)
Affinity DataIC50: 100nMAssay Description:Inhibition of HIPK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 2(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563537BDBM50563537(CHEMBL4789951)
Affinity DataIC50: 102nMAssay Description:Inhibition of human recombinant HIPK2 using myelin substrate by radiometric scintillation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 2(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563533BDBM50563533(CHEMBL4777288)
Affinity DataIC50: 119nMAssay Description:Inhibition of human recombinant HIPK2 using myelin substrate by radiometric scintillation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 2(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50242737BDBM50242737((R,Z)-5-(2,6-dichlorobenzylsulfonyl)-3-((3,5-dimet...)
Affinity DataKd:  120nMAssay Description:Binding constant for HIPK2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 2(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563534BDBM50563534(CHEMBL4778153)
Affinity DataIC50: 123nMAssay Description:Inhibition of human recombinant HIPK2 using myelin substrate by radiometric scintillation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 2(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 17055BDBM17055((9S)-9-[(dimethylamino)methyl]-6,7,10,11-tetrahydr...)
Affinity DataKd:  140nMAssay Description:Binding constant for HIPK2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 2(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 2579BDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 146nMAssay Description:Inhibition of human HIPK2 using MBP as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 2(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563544BDBM50563544(CHEMBL4778370)
Affinity DataIC50: 172nMAssay Description:Inhibition of human recombinant HIPK2 using myelin substrate by radiometric scintillation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 2(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563535BDBM50563535(CHEMBL4791451)
Affinity DataIC50: 179nMAssay Description:Inhibition of human recombinant HIPK2 using myelin substrate by radiometric scintillation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 2(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 2579BDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataKd:  190nMAssay Description:Binding constant for HIPK2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 2(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 15138BDBM15138(Biochemistry 469551 Compound 11 | 5-indazolyl pyri...)
Affinity DataKd:  220nMAssay Description:Binding constant for HIPK2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 2(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50355504BDBM50355504(CHEMBL1908393)
Affinity DataKd:  220nMAssay Description:Binding constant for HIPK2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 2(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563536BDBM50563536(CHEMBL4741919)
Affinity DataIC50: 260nMAssay Description:Inhibition of human recombinant HIPK2 using myelin substrate by radiometric scintillation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 2(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 25045BDBM25045(CHEMBL538346 | mTOR Inhibitor, PI103 | PI-103 | 3-...)
Affinity DataKd:  290nMAssay Description:Binding constant for HIPK2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
Displayed 1 to 50 (of 278 total ) | Next | Last >>
Jump to: