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TargetWD repeat-containing protein 48(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50069762(CHEMBL3182437 | ML323 | US9802904, 87)
Affinity DataEC50:  3.00E+3nMAssay Description:Inhibition of human USP1/UAF1 in human H1299 cells assessed as reduction in colony formation after 7 daysMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetWD repeat-containing protein 48(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50365463(CHEMBL1232461)
Affinity DataKd:  31nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM707434(US20240409538, Example 38)
Affinity DataIC50: 5.44nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetWD repeat-containing protein 48(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50646522(CHEMBL5593758)
Affinity DataIC50: 7.10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetWD repeat-containing protein 48(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50646511(CHEMBL5595820)
Affinity DataIC50: 8.80nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM707433(US20240409538, Example 37)
Affinity DataIC50: 9.53nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetWD repeat-containing protein 48(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50646521(CHEMBL5593526)
Affinity DataIC50: 11nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM707417(US20240409538, Example 18)
Affinity DataIC50: 11.2nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM707423(US20240409538, Example 25)
Affinity DataIC50: 11.6nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM707422(US20240409538, Example 24)
Affinity DataIC50: 11.8nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetWD repeat-containing protein 48(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50646520(CHEMBL5583831)
Affinity DataIC50: 13nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM707416(US20240409538, Example 16)
Affinity DataIC50: 15.8nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetWD repeat-containing protein 48(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50646519(CHEMBL5592698)
Affinity DataIC50: 16nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM707419(US20240409538, Example 21)
Affinity DataIC50: 16.1nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM50069762(CHEMBL3182437 | ML323 | US9802904, 87)
Affinity DataIC50: 17nMAssay Description:This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM707415(US20240409538, Example 15)
Affinity DataIC50: 17.9nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM707435(US20240409538, Example 39)
Affinity DataIC50: 18.8nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetWD repeat-containing protein 48(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50646510(CHEMBL5594891)
Affinity DataIC50: 19nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM707436(US20240409538, Example 40)
Affinity DataIC50: 19.9nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetWD repeat-containing protein 48(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM580031(US11485736, Compound Table 3.15)
Affinity DataIC50: 21nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetWD repeat-containing protein 48(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50646509(CHEMBL5593671)
Affinity DataIC50: 23nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetWD repeat-containing protein 48(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50646527(CHEMBL5595458)
Affinity DataIC50: 23nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM707426(US20240409538, Example 28)
Affinity DataIC50: 26nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM707414(US20240409538, Example 14)
Affinity DataIC50: 30.6nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM352028(US9802904, 89)
Affinity DataIC50: 34nMAssay Description:This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
Go to US Patent

TargetWD repeat-containing protein 48(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50646500(CHEMBL5592420)
Affinity DataIC50: 34nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM707437(US20240409538, Example 41)
Affinity DataIC50: 34.2nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM707427(US20240409538, Example 29)
Affinity DataIC50: 34.6nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM707439(US20240409538, Example 43)
Affinity DataIC50: 38.9nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM707412(US20240409538, Example 5)
Affinity DataIC50: 39.1nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM707424(US20240409538, Example 26)
Affinity DataIC50: 39.5nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetWD repeat-containing protein 48(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50646502(CHEMBL5592802)
Affinity DataIC50: 40nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM707428(US20240409538, Example 30)
Affinity DataIC50: 41.4nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM350387(US9802904, 60)
Affinity DataIC50: 43nMAssay Description:This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM352011(US9802904, 72)
Affinity DataIC50: 43nMAssay Description:This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM352013(US9802904, 74)
Affinity DataIC50: 48nMAssay Description:This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
Go to US Patent

TargetWD repeat-containing protein 48(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM352011(US9802904, 72)
Affinity DataIC50: 50nMAssay Description:Inhibition of human USP1/UAF1 using Ub-AMC substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM707429(US20240409538, Example 31)
Affinity DataIC50: 57.5nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetWD repeat-containing protein 48(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50646524(CHEMBL5595535)
Affinity DataIC50: 60nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM351737(US9802904, 61)
Affinity DataIC50: 61nMAssay Description:This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM352018(US9802904, 79)
Affinity DataIC50: 61nMAssay Description:This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM352025(US9802904, 86)
Affinity DataIC50: 61nMAssay Description:This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM707411(US20240409538, Example 4)
Affinity DataIC50: 66.6nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM350386(US9802904, 59)
Affinity DataIC50: 68nMAssay Description:This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
Go to US Patent

TargetWD repeat-containing protein 48(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM352025(US9802904, 86)
Affinity DataIC50: 70nMAssay Description:Inhibition of human USP1/UAF1 using Ub-AMC substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetWD repeat-containing protein 48(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50497350(CHEMBL3187668)
Affinity DataIC50: 70nMAssay Description:Inhibition of human USP1/UAF1 using Ub-AMC substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM50069762(CHEMBL3182437 | ML323 | US9802904, 87)
Affinity DataIC50: 76nMAssay Description:This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
Go to US Patent

TargetWD repeat-containing protein 48(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50069762(CHEMBL3182437 | ML323 | US9802904, 87)
Affinity DataIC50: 76nMAssay Description:Inhibition of human USP1/UAF1 using Ub-AMC substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM707425(US20240409538, Example 27)
Affinity DataIC50: 77.5nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM707440(US20240409538, Example 44)
Affinity DataIC50: 78.3nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

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