Compile Data Set for Download or QSAR
Report error Found 441 of affinity data for UniProtKB/TrEMBL: Q8R4B8
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50632375(CHEMBL5430841)
Affinity DataKd:  5.87E+3nMAssay Description:Binding affinity to CMS sensor chip immobilized His-SUMO-tagged mouse NLRP3 expressed in Escherichia coli assessed as dissociation constant by SPR an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50605051(CHEMBL5184952)
Affinity DataIC50: 0.230nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed mouse BMDM cells assessed as reduction in ATP induced IL-1beta release pretreated for 15 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50155926(CHEMBL3183703)
Affinity DataIC50: 0.390nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed mouse BMDM cells assessed as reduction in ATP induced IL-1beta release pretreated for 15 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50505850(Dapansutrile | OLT-1177 | OLT1177)
Affinity DataIC50: 1nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed mouse J774A.1 cells assessed as reduction in IL-1beta level preincubated for 30 mins follow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50505850(Dapansutrile | OLT-1177 | OLT1177)
Affinity DataIC50: 1nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed mouse J774.A1 cells assessed as reduction in IL-1beta level incubated for 1 hr followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50632650(CHEMBL5421905)
Affinity DataIC50: 6.90nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-treated mouse BMDM cells assessed as inhibition of ATP-stimulated IL-1beta release incubated for 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50155926(CHEMBL3183703)
Affinity DataIC50: 7.5nMAssay Description:Inhibition of NLRP3 in mouse BMDM cells preincubated for 30 mins followed by ATP addition by ELISA analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2017
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50155926(CHEMBL3183703)
Affinity DataIC50: 7.5nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-stimulated mouse BMDM assessed as reduction in NLRP3 inflammasome-induced IL-1beta production prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2018
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50155926(CHEMBL3183703)
Affinity DataIC50: 7.5nMAssay Description:Inhibition of NLRP3 in LPS/ATP-treated mouse bone marrow derived macrophages assessed as reduction in NLRP3 inflammasome activation by measuring redu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50155926(CHEMBL3183703)
Affinity DataIC50: 7.5nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed mouse bone marrow derived macrophages assessed as reduction in IL-1beta level preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50155926(CHEMBL3183703)
Affinity DataIC50: 7.5nMAssay Description:Inhibition of NLRP3 in mouse BMDMsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50155926(CHEMBL3183703)
Affinity DataIC50: 7.5nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS/nigericin-treated mouse BMDM cells assessed as inhibition of LPS and nigericin-induced IL-1beta pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50598221(CHEMBL4288808)
Affinity DataIC50: 8nMAssay Description:Inhibition of NLRP3 inflammasome in LPS-primed mouse J774.A1 cells assessed as reduction in IL-1beta secretion preincubated for 30 mins followed by A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50632651(CHEMBL5422387)
Affinity DataIC50: 8.60nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-treated mouse BMDM cells assessed as inhibition of ATP-stimulated IL-1beta release incubated for 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50155926(CHEMBL3183703)
Affinity DataIC50: 13nMAssay Description:Inhibition of NLRP3 inflammasome in mouse JJ74.A1 cells assessed as inhibition of LPS/ATP-induced IL-1 beta release stimulated with LPS for 4.5 hs fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50634192(CHEMBL5396485)
Affinity DataIC50: 14nMAssay Description:Inhibition of NLRP3 in mouse BMDM cells assessed as reduction in IL-1beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50155926(CHEMBL3183703)
Affinity DataIC50: 14nMAssay Description:Inhibition of NLRP3 inflammasome in mouse JJ74.A1 cells assessed as inhibition of LPS/ATP-induced IL-1 beta secretion primed with LPS for 4.5 hs foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50632652(CHEMBL5436366)
Affinity DataIC50: 20nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-treated mouse BMDM cells assessed as inhibition of ATP-stimulated IL-1beta release incubated for 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50155926(CHEMBL3183703)
Affinity DataIC50: 22nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed mouse J774.A1 cells assessed as reduction in IL-1beta secretion preincubated for 1 hr follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50155926(CHEMBL3183703)
Affinity DataIC50: 23nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS/nigericin-treated mouse J774A.1 cells assessed as decrease in LDH release pretreated for 0.5 hrs f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50155926(CHEMBL3183703)
Affinity DataIC50: 23nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS/nigericin-treated mouse J774A.1 cells assessed as decrease in IL-1beta level pretreated for 0.5 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50628782(CHEMBL5434669)
Affinity DataIC50: 25nMAssay Description:Inhibition of NLRP3 inflammasome in mouse JJ74.A1 cells assessed as inhibition of LPS/ATP-induced IL-1 beta secretion primed with LPS for 4.5 hs foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50593017(CHEMBL5196305)
Affinity DataIC50: 32nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed mouse J774.A1 cells assessed as reduction in IL-1beta secretion preincubated for 1 hr follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50155926(CHEMBL3183703)
Affinity DataIC50: 40nMAssay Description:Inhibition of NLRP3 in mouse peritoneal macrophages assessed as inhibition of LPS and ATP-induced IL-1beta production pre-stimulated with LPS for 4.5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50155926(CHEMBL3183703)
Affinity DataIC50: 40nMAssay Description:Inhibition of NLRP3 in mouse peritoneal macrophages assessed as inhibition of LPS and ATP-induced IL-1beta production pre-stimulated with LPS for 4.5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50069989(CHEMBL325041 | (R)-3-methyl-1-((S)-3-phenyl-2-(pyr...)
Affinity DataIC50: 41nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed mouse J774.A1 cells assessed as reduction in IL-1beta secretion preincubated for 1 hr follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50505855(CHEMBL4468698)
Affinity DataIC50: 42nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed mouse bone marrow derived macrophages assessed as reduction in IL-1beta level preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50593025(CHEMBL5187619)
Affinity DataIC50: 46nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed mouse J774.A1 cells assessed as reduction in IL-1beta secretion preincubated for 1 hr follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50593013(CHEMBL483266)
Affinity DataIC50: 49nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed mouse J774.A1 cells assessed as reduction in IL-1beta secretion preincubated for 1 hr follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50593023(CHEMBL5183504)
Affinity DataIC50: 49nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed mouse J774.A1 cells assessed as reduction in IL-1beta secretion preincubated for 1 hr follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50607509(CHEMBL5219789)
Affinity DataIC50: 63nMAssay Description:Inhibition of NLRP3 induced IL-1beta release in LPS/nigericin-treated mouse BMDM cells preincubated with LPS for 3 hrs followed by compound addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50628784(CHEMBL5414644)
Affinity DataIC50: 63nMAssay Description:Inhibition of NLRP3 inflammasome in mouse JJ74.A1 cells assessed as inhibition of LPS/ATP-induced IL-1 beta secretion primed with LPS for 4.5 hs foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50593016(CHEMBL5195292)
Affinity DataIC50: 65nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed mouse J774.A1 cells assessed as reduction in IL-1beta secretion preincubated for 1 hr follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50593018(CHEMBL5171338)
Affinity DataIC50: 74nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed mouse J774.A1 cells assessed as reduction in IL-1beta secretion preincubated for 1 hr follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50593020(CHEMBL5177370)
Affinity DataIC50: 76nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed mouse J774.A1 cells assessed as reduction in IL-1beta secretion preincubated for 1 hr follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50593011(CHEMBL5208208)
Affinity DataIC50: 79nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed mouse J774.A1 cells assessed as reduction in IL-1beta secretion preincubated for 1 hr follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50593009(CHEMBL5206815)
Affinity DataIC50: 81nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed mouse J774.A1 cells assessed as reduction in IL-1beta secretion preincubated for 1 hr follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50593021(CHEMBL5181924)
Affinity DataIC50: 85nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed mouse J774.A1 cells assessed as reduction in IL-1beta secretion preincubated for 1 hr follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50593001(CHEMBL5188468)
Affinity DataIC50: 87nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed mouse J774.A1 cells assessed as reduction in IL-1beta secretion preincubated for 1 hr follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50593024(CHEMBL5174430)
Affinity DataIC50: 91nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed mouse J774.A1 cells assessed as reduction in IL-1beta secretion preincubated for 1 hr follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50505850(Dapansutrile | OLT-1177 | OLT1177)
Affinity DataIC50: 100nMAssay Description:Inhibition of NLRP3 in mouse J774A.1 cells infected with FLA-ST assessed as inhibition of LPS- induced IL-1beta production by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50607509(CHEMBL5219789)
Affinity DataIC50: 100nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS and ATP-stimulated mouse whole blood assessed as reduction in IL-1beta release preincubated for 3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50634161(CHEMBL5394498)
Affinity DataIC50: 100nMAssay Description:Inhibition of NLRP3 in mouse BMDM cells assessed as reduction in IL-1beta production preincubated for 30 mins followed by ATP addition measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50634180(CHEMBL5407508)
Affinity DataIC50: 100nMAssay Description:Inhibition of NLRP3 in mouse BMDM cells assessed as reduction in IL-1beta production measured after 3 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50634194(CHEMBL5423418)
Affinity DataIC50: 100nMAssay Description:Inhibition of NLRP3 in mouse BMDM assessed as reduction in IL-1beta production preincubated for 3 hrs followed by ATP measured after 45 mins by ELISA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50634191(CHEMBL5397385)
Affinity DataIC50: 117nMAssay Description:Inhibition of NLRP3 in mouse BMDM cells assessed as reduction in IL-1beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50465504(CHEMBL4277889)
Affinity DataIC50: 120nMAssay Description:Inhibition of NLRP3 in mouse BMDM assessed as reduction in LPS-stimulated IL-1beta levels pre-incubated with LPS for 4.5 hrs followed by incubation f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50598211(CHEMBL5173327)
Affinity DataIC50: 120nMAssay Description:Inhibition of NLRP3 inflammasome in LPS-primed mouse J774.A1 cells assessed as reduction in IL-1beta secretion preincubated for 30 mins followed by A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50598210(CHEMBL5208422)
Affinity DataIC50: 130nMAssay Description:Inhibition of NLRP3 inflammasome in LPS-primed mouse J774.A1 cells assessed as reduction in IL-1beta secretion preincubated for 30 mins followed by A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50631252(CHEMBL5413950)
Affinity DataIC50: 130nMAssay Description:Inhibition of NLRP3 inflammasome in mouse JJ74.A1 cells assessed as inhibition of LPS/ATP-induced IL-1 beta release stimulated with LPS for 4.5 hs fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
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