Compile Data Set for Download or QSAR
Report error Found 177 of affinity data for UniProtKB/TrEMBL: Q8NHU3
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50282224(CHEMBL4172856)
Affinity DataKd:  38nMAssay Description:Binding affinity to full length C-terminal FLAG tagged human SMS2 expressed in HEK293 cells after 120 mins by AS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2020
Entry Details Article
PubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50282224(CHEMBL4172856)
Affinity DataKd:  240nMAssay Description:Binding affinity to full length C-terminal FLAG tagged human SMS2 S217A mutant expressed in HEK293 cells after 120 mins by AS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2020
Entry Details Article
PubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50282224(CHEMBL4172856)
Affinity DataKd: >3.00E+3nMAssay Description:Binding affinity to full length C-terminal FLAG tagged human SMS2 S227A mutant expressed in HEK293 cells after 120 mins by AS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2020
Entry Details Article
PubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50282224(CHEMBL4172856)
Affinity DataKd: >3.00E+3nMAssay Description:Binding affinity to full length C-terminal FLAG tagged human SMS2 H229A mutant expressed in HEK293 cells after 120 mins by AS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2020
Entry Details Article
PubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50282224(CHEMBL4172856)
Affinity DataKd:  30nMAssay Description:Binding affinity to full length C-terminal FLAG tagged human SMS2 H272A mutant expressed in HEK293 cells after 120 mins by AS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2020
Entry Details Article
PubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50282224(CHEMBL4172856)
Affinity DataKd:  28nMAssay Description:Binding affinity to full length C-terminal FLAG tagged human SMS2 D276A mutant expressed in HEK293 cells after 120 mins by AS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2020
Entry Details Article
PubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50282224(CHEMBL4172856)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of full length C-terminal FLAG tagged human SMS2 expressed in HEK293 cell membranes using DMPC-d72 and C17-ceramide as substrate preincuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2020
Entry Details Article
PubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50282208(CHEMBL4177314)
Affinity DataIC50: 16nMAssay Description:Inhibition of full length C-terminal FLAG tagged human SMS2 expressed in HEK293 cell membranes using DMPC-d72 and C17-ceramide as substrate preincuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2020
Entry Details Article
PubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50545122(CHEMBL4646354)
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant C-terminal FLAG-tagged SMS2 expressed in Freestyle293 cell membrane using C14-phosphatidylcholineD72 and C17-ceramide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50545129(CHEMBL4645607)
Affinity DataIC50: 45nMAssay Description:Inhibition of human recombinant C-terminal FLAG-tagged SMS2 expressed in Freestyle293 cell membrane using C14-phosphatidylcholineD72 and C17-ceramide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50545128(CHEMBL4641888)
Affinity DataIC50: 47nMAssay Description:Inhibition of human recombinant C-terminal FLAG-tagged SMS2 expressed in Freestyle293 cell membrane using C14-phosphatidylcholineD72 and C17-ceramide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50458938(CHEMBL4203399)
Affinity DataIC50: 90nMAssay Description:Inhibition of human SMS2 using C6-NBD-ceramide and DMPC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50529830(CHEMBL4540510)
Affinity DataIC50: 91nMAssay Description:Inhibition of purified SMS2 (unknown origin) using C6-NBD-Ceramide and DMPC as substrates preincubated for 5 mins followed by substrate addition and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50529830(CHEMBL4540510)
Affinity DataIC50: 91nMAssay Description:Inhibition of purified SMS2 (unknown origin) using C6-NBD-Ceramide and DMPC as substrates preincubated for 5 mins followed by substrate addition and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50545123(CHEMBL4638337)
Affinity DataIC50: 91nMAssay Description:Inhibition of human recombinant C-terminal FLAG-tagged SMS2 expressed in Freestyle293 cell membrane using C14-phosphatidylcholineD72 and C17-ceramide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50458921(CHEMBL4204352)
Affinity DataIC50: 100nMAssay Description:Inhibition of human SMS2 using C6-NBD-ceramide and DMPC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50458927(CHEMBL4214637)
Affinity DataIC50: 100nMAssay Description:Inhibition of human SMS2 using C6-NBD-ceramide and DMPC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50458919(CHEMBL4207944)
Affinity DataIC50: 110nMAssay Description:Inhibition of human SMS2 using C6-NBD-ceramide and DMPC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50545119(CHEMBL4634669)
Affinity DataIC50: 120nMAssay Description:Inhibition of human recombinant C-terminal FLAG-tagged SMS2 expressed in Freestyle293 cell membrane using C14-phosphatidylcholineD72 and C17-ceramide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50545126(CHEMBL4646540)
Affinity DataIC50: 130nMAssay Description:Inhibition of human recombinant C-terminal FLAG-tagged SMS2 expressed in Freestyle293 cell membrane using C14-phosphatidylcholineD72 and C17-ceramide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50458939(CHEMBL4202436)
Affinity DataIC50: 150nMAssay Description:Inhibition of human SMS2 using C6-NBD-ceramide and DMPC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50458929(CHEMBL4206801)
Affinity DataIC50: 160nMAssay Description:Inhibition of human SMS2 using C6-NBD-ceramide and DMPC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50458931(CHEMBL4205965)
Affinity DataIC50: 190nMAssay Description:Inhibition of human SMS2 using C6-NBD-ceramide and DMPC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50545120(CHEMBL4634697)
Affinity DataIC50: 210nMAssay Description:Inhibition of human recombinant C-terminal FLAG-tagged SMS2 expressed in Freestyle293 cell membrane using C14-phosphatidylcholineD72 and C17-ceramide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50458926(CHEMBL4211357)
Affinity DataIC50: 240nMAssay Description:Inhibition of human SMS2 using C6-NBD-ceramide and DMPC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50458937(CHEMBL4217275)
Affinity DataIC50: 240nMAssay Description:Inhibition of human SMS2 using C6-NBD-ceramide and DMPC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50458942(CHEMBL4202973)
Affinity DataIC50: 270nMAssay Description:Inhibition of human SMS2 using C6-NBD-ceramide and DMPC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50545127(CHEMBL4644293)
Affinity DataIC50: 300nMAssay Description:Inhibition of human recombinant C-terminal FLAG-tagged SMS2 expressed in Freestyle293 cell membrane using C14-phosphatidylcholineD72 and C17-ceramide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50458934(CHEMBL4212291)
Affinity DataIC50: 340nMAssay Description:Inhibition of human SMS2 using C6-NBD-ceramide and DMPC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50545118(CHEMBL4637599)
Affinity DataIC50: 350nMAssay Description:Inhibition of human recombinant C-terminal FLAG-tagged SMS2 expressed in Freestyle293 cell membrane using C14-phosphatidylcholineD72 and C17-ceramide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50545116(CHEMBL4649105)
Affinity DataIC50: 380nMAssay Description:Inhibition of human recombinant C-terminal FLAG-tagged SMS2 expressed in Freestyle293 cell membrane using C14-phosphatidylcholineD72 and C17-ceramide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50545124(CHEMBL4639746)
Affinity DataIC50: 380nMAssay Description:Inhibition of human recombinant C-terminal FLAG-tagged SMS2 expressed in Freestyle293 cell membrane using C14-phosphatidylcholineD72 and C17-ceramide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50282210(CHEMBL4162182)
Affinity DataIC50: 410nMAssay Description:Inhibition of human SMS2 expressed in HEK293T cells using C2-ceramide as substrate preincubated for 60 mins followed by substrate addition measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2020
Entry Details Article
PubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50529838(CHEMBL4544787)
Affinity DataIC50: 430nMAssay Description:Inhibition of SMS2 (unknown origin) over-expressed in H5 insect cell lysate using C6-NBD-Ceramide and DMPC as substrates preincubated for 30 mins fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50529838(CHEMBL4544787)
Affinity DataIC50: 430nMAssay Description:Inhibition of SMS2 (unknown origin) over-expressed in H5 insect cell lysate using C6-NBD-Ceramide and DMPC as substrates preincubated for 30 mins fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50282210(CHEMBL4162182)
Affinity DataIC50: 470nMAssay Description:Inhibition of full length C-terminal FLAG tagged human SMS2 expressed in HEK293 cell membranes using DMPC-d72 and C17-ceramide as substrate preincuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2020
Entry Details Article
PubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50458932(CHEMBL4217676)
Affinity DataIC50: 470nMAssay Description:Inhibition of human SMS2 using C6-NBD-ceramide and DMPC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50529852(CHEMBL4472866)
Affinity DataIC50: 470nMAssay Description:Inhibition of SMS2 (unknown origin) over-expressed in H5 insect cell lysate using C6-NBD-Ceramide and DMPC as substrates preincubated for 30 mins fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50529852(CHEMBL4472866)
Affinity DataIC50: 470nMAssay Description:Inhibition of SMS2 (unknown origin) over-expressed in H5 insect cell lysate using C6-NBD-Ceramide and DMPC as substrates preincubated for 30 mins fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50545121(CHEMBL4638097)
Affinity DataIC50: 480nMAssay Description:Inhibition of human recombinant C-terminal FLAG-tagged SMS2 expressed in Freestyle293 cell membrane using C14-phosphatidylcholineD72 and C17-ceramide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50458947(CHEMBL4216327)
Affinity DataIC50: 520nMAssay Description:Inhibition of human SMS2 using C6-NBD-ceramide and DMPC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50529848(CHEMBL4452926)
Affinity DataIC50: 520nMAssay Description:Inhibition of SMS2 (unknown origin) over-expressed in H5 insect cell lysate using C6-NBD-Ceramide and DMPC as substrates preincubated for 30 mins fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50529848(CHEMBL4452926)
Affinity DataIC50: 520nMAssay Description:Inhibition of SMS2 (unknown origin) over-expressed in H5 insect cell lysate using C6-NBD-Ceramide and DMPC as substrates preincubated for 30 mins fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50545114(CHEMBL4644982)
Affinity DataIC50: 610nMAssay Description:Inhibition of human recombinant C-terminal FLAG-tagged SMS2 expressed in Freestyle293 cell membrane using C14-phosphatidylcholineD72 and C17-ceramide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50458940(CHEMBL4211679)
Affinity DataIC50: 670nMAssay Description:Inhibition of human SMS2 using C6-NBD-ceramide and DMPC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50529822(CHEMBL4558411)
Affinity DataIC50: 670nMAssay Description:Inhibition of SMS2 (unknown origin) over-expressed in H5 insect cell lysate using C6-NBD-Ceramide and DMPC as substrates preincubated for 30 mins fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50529836(CHEMBL4448125)
Affinity DataIC50: 670nMAssay Description:Inhibition of SMS2 (unknown origin) over-expressed in H5 insect cell lysate using C6-NBD-Ceramide and DMPC as substrates preincubated for 30 mins fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50529822(CHEMBL4558411)
Affinity DataIC50: 670nMAssay Description:Inhibition of SMS2 (unknown origin) over-expressed in H5 insect cell lysate using C6-NBD-Ceramide and DMPC as substrates preincubated for 30 mins fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50529836(CHEMBL4448125)
Affinity DataIC50: 670nMAssay Description:Inhibition of SMS2 (unknown origin) over-expressed in H5 insect cell lysate using C6-NBD-Ceramide and DMPC as substrates preincubated for 30 mins fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50529833(CHEMBL4559796)
Affinity DataIC50: 690nMAssay Description:Inhibition of SMS2 (unknown origin) over-expressed in H5 insect cell lysate using C6-NBD-Ceramide and DMPC as substrates preincubated for 30 mins fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
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