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Report error Found 162 of affinity data for UniProtKB/TrEMBL: Q61263
TargetSterol O-acyltransferase 1(Mouse)
Kowa

Curated by ChEMBL
LigandPNGBDBM50462683(CHEMBL4247249)
Affinity DataIC50: 7nMAssay Description:Inhibition of ACAT1 in mouse J774 cells assessed as reduction in esterified cholesterol accumulation after 18 hrs in presence of 25-hydroxycholestero...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Mouse)
Kowa

Curated by ChEMBL
LigandPNGBDBM50450346(CHEMBL300883)
Affinity DataIC50: 10nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in J774 Macrophage cell cultureMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details

TargetSterol O-acyltransferase 1(Mouse)
Kowa

Curated by ChEMBL
LigandPNGBDBM50285443(Benzooxazol-2-yl-[5-(4,5-diphenyl-1H-imidazol-2-yl...)
Affinity DataIC50: 20nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase in J774 Macrophage cell cultureMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSterol O-acyltransferase 1(Mouse)
Kowa

Curated by ChEMBL
LigandPNGBDBM50462702(CHEMBL4241747)
Affinity DataIC50: 30nMAssay Description:Inhibition of ACAT1 in mouse J774 cells assessed as reduction in esterified cholesterol accumulation after 18 hrs in presence of 25-hydroxycholestero...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Mouse)
Kowa

Curated by ChEMBL
LigandPNGBDBM50462684(CHEMBL4243015)
Affinity DataIC50: 40nMAssay Description:Inhibition of ACAT1 in mouse J774 cells assessed as reduction in esterified cholesterol accumulation after 18 hrs in presence of 25-hydroxycholestero...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Mouse)
Kowa

Curated by ChEMBL
LigandPNGBDBM50462661(CHEMBL4240947)
Affinity DataIC50: 43nMAssay Description:Inhibition of ACAT1 in mouse J774 cells assessed as reduction in esterified cholesterol accumulation after 18 hrs in presence of 25-hydroxycholestero...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Mouse)
Kowa

Curated by ChEMBL
LigandPNGBDBM50462653(CHEMBL4245998)
Affinity DataIC50: 48nMAssay Description:Inhibition of ACAT1 in mouse J774 cells assessed as reduction in esterified cholesterol accumulation after 18 hrs in presence of 25-hydroxycholestero...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Mouse)
Kowa

Curated by ChEMBL
LigandPNGBDBM50285435(Benzooxazol-2-yl-{5-[4,5-bis-(4-dimethylamino-phen...)
Affinity DataIC50: 50nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase in J774 Macrophage cell cultureMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSterol O-acyltransferase 1(Mouse)
Kowa

Curated by ChEMBL
LigandPNGBDBM50462652(CHEMBL4248936)
Affinity DataIC50: 59nMAssay Description:Inhibition of ACAT1 in mouse J774 cells assessed as reduction in esterified cholesterol accumulation after 18 hrs in presence of 25-hydroxycholestero...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Mouse)
Kowa

Curated by ChEMBL
LigandPNGBDBM50450361(CHEMBL300913)
Affinity DataIC50: 60nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in J774 Macrophage cell cultureMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details

TargetSterol O-acyltransferase 1(Mouse)
Kowa

Curated by ChEMBL
LigandPNGBDBM50450357(CHEMBL48164)
Affinity DataIC50: 60nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in J774 Macrophage cell cultureMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details

TargetSterol O-acyltransferase 1(Mouse)
Kowa

Curated by ChEMBL
LigandPNGBDBM50285432(1N,1N-dimethyl-4-[2-{5-[4,5-di(4-dimethylaminophen...)
Affinity DataIC50: 60nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase in J774 Macrophage cell cultureMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSterol O-acyltransferase 1(Mouse)
Kowa

Curated by ChEMBL
LigandPNGBDBM50069900(CHEMBL101309 | [2-(2,4,6-Triisopropyl-phenyl)-acet...)
Affinity DataIC50: 60nMAssay Description:Inhibition of ACAT1 in mouse IC21 cells in absence of BSAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Mouse)
Kowa

Curated by ChEMBL
LigandPNGBDBM50285420(Benzooxazol-2-yl-{5-[4,5-bis-(4-methoxy-phenyl)-1H...)
Affinity DataIC50: 70nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase in J774 Macrophage cell cultureMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSterol O-acyltransferase 1(Mouse)
Kowa

Curated by ChEMBL
LigandPNGBDBM50285447({5-[4,5-Bis-(4-methoxy-phenyl)-1H-imidazol-2-ylsul...)
Affinity DataIC50: 70nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase in J774 Macrophage cell cultureMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSterol O-acyltransferase 1(Mouse)
Kowa

Curated by ChEMBL
LigandPNGBDBM50285442(Benzooxazol-2-yl-{5-[4,5-bis-(4-methoxy-phenyl)-1H...)
Affinity DataIC50: 80nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase in J774 Macrophage cell cultureMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSterol O-acyltransferase 1(Mouse)
Kowa

Curated by ChEMBL
LigandPNGBDBM50285434(Benzooxazol-2-yl-{5-[4,5-bis-(4-methoxy-phenyl)-1H...)
Affinity DataIC50: 80nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase in J774 Macrophage cell cultureMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSterol O-acyltransferase 1(Mouse)
Kowa

Curated by ChEMBL
LigandPNGBDBM50285444(1N,1N-dimethyl-4-{5-(4-dimethylaminophenyl)-2-[5-(...)
Affinity DataIC50: 80nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase in J774 Macrophage cell cultureMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSterol O-acyltransferase 1(Mouse)
Kowa

Curated by ChEMBL
LigandPNGBDBM50450366(CHEMBL49265)
Affinity DataIC50: 90nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in J774 Macrophage cell cultureMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details

TargetSterol O-acyltransferase 1(Mouse)
Kowa

Curated by ChEMBL
LigandPNGBDBM50285427(Benzooxazol-2-yl-{5-[4,5-bis-(4-methoxy-phenyl)-1H...)
Affinity DataIC50: 90nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase in J774 Macrophage cell cultureMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSterol O-acyltransferase 1(Mouse)
Kowa

Curated by ChEMBL
LigandPNGBDBM50285430(Benzooxazol-2-yl-{5-[4,5-bis-(4-dimethylamino-phen...)
Affinity DataIC50: 90nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase in J774 Macrophage cell cultureMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSterol O-acyltransferase 1(Mouse)
Kowa

Curated by ChEMBL
LigandPNGBDBM50051901(1-[5-(4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-penty...)
Affinity DataIC50: 90nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase in J774 Macrophage cell cultureMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSterol O-acyltransferase 1(Mouse)
Kowa

Curated by ChEMBL
LigandPNGBDBM50450345(CHEMBL51643)
Affinity DataIC50: 100nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in J774 Macrophage cell cultureMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details

TargetSterol O-acyltransferase 1(Mouse)
Kowa

Curated by ChEMBL
LigandPNGBDBM50462670(CHEMBL4239138)
Affinity DataIC50: 100nMAssay Description:Inhibition of ACAT1 in mouse J774 cells assessed as reduction in esterified cholesterol accumulation after 18 hrs in presence of 25-hydroxycholestero...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Mouse)
Kowa

Curated by ChEMBL
LigandPNGBDBM50462703(CHEMBL4249787)
Affinity DataIC50: 100nMAssay Description:Inhibition of ACAT1 in mouse J774 cells assessed as reduction in esterified cholesterol accumulation after 18 hrs in presence of 25-hydroxycholestero...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Mouse)
Kowa

Curated by ChEMBL
LigandPNGBDBM50462706(CHEMBL4249263)
Affinity DataIC50: 100nMAssay Description:Inhibition of ACAT1 in mouse J774 cells assessed as reduction in esterified cholesterol accumulation after 18 hrs in presence of 25-hydroxycholestero...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Mouse)
Kowa

Curated by ChEMBL
LigandPNGBDBM50462677(CHEMBL4245984)
Affinity DataIC50: 180nMAssay Description:Inhibition of ACAT1 in mouse J774 cells assessed as reduction in esterified cholesterol accumulation after 18 hrs in presence of 25-hydroxycholestero...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Mouse)
Kowa

Curated by ChEMBL
LigandPNGBDBM50462682(CHEMBL4239248)
Affinity DataIC50: 180nMAssay Description:Inhibition of ACAT1 in mouse J774 cells assessed as reduction in esterified cholesterol accumulation after 18 hrs in presence of 25-hydroxycholestero...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Mouse)
Kowa

Curated by ChEMBL
LigandPNGBDBM50450364(CHEMBL50171)
Affinity DataIC50: 190nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in J774 Macrophage cell cultureMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details

TargetSterol O-acyltransferase 1(Mouse)
Kowa

Curated by ChEMBL
LigandPNGBDBM50285419(2-{5-[4,5-di(4-methoxyphenyl)-1H-2-imidazolylsulfa...)
Affinity DataIC50: 200nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase in J774 Macrophage cell cultureMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSterol O-acyltransferase 1(Mouse)
Kowa

Curated by ChEMBL
LigandPNGBDBM50287517(3-(2,6-Diisopropyl-phenyl)-1-(2-dodecyl-2H-tetrazo...)
Affinity DataIC50: 240nMAssay Description:Compound was tested for its ability to penetrate the cell wall and inhibit macrophage ACAT in cell culture using murine IC-21 macrophages (MAI)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSterol O-acyltransferase 1(Mouse)
Kowa

Curated by ChEMBL
LigandPNGBDBM50285433(1N,1N-dimethyl-4-{5-(4-dimethylaminophenyl)-2-[5-(...)
Affinity DataIC50: 250nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase in J774 Macrophage cell cultureMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSterol O-acyltransferase 1(Mouse)
Kowa

Curated by ChEMBL
LigandPNGBDBM50462658(CHEMBL4238015)
Affinity DataIC50: 280nMAssay Description:Inhibition of ACAT1 in mouse J774 cells assessed as reduction in esterified cholesterol accumulation after 18 hrs in presence of 25-hydroxycholestero...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Mouse)
Kowa

Curated by ChEMBL
LigandPNGBDBM50462659(CHEMBL4248950)
Affinity DataIC50: 300nMAssay Description:Inhibition of ACAT1 in mouse J774 cells assessed as reduction in esterified cholesterol accumulation after 18 hrs in presence of 25-hydroxycholestero...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Mouse)
Kowa

Curated by ChEMBL
LigandPNGBDBM50462665(CHEMBL4248172)
Affinity DataIC50: 310nMAssay Description:Inhibition of ACAT1 in mouse J774 cells assessed as reduction in esterified cholesterol accumulation after 18 hrs in presence of 25-hydroxycholestero...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Mouse)
Kowa

Curated by ChEMBL
LigandPNGBDBM50005944(2,2-Dimethyl-dodecanoic acid (2,4,6-trimethoxy-phe...)
Affinity DataIC50: 310nMAssay Description:Inhibition of ACAT1 in mouse J774 cells assessed as reduction in esterified cholesterol accumulation after 18 hrs in presence of 25-hydroxycholestero...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSterol O-acyltransferase 1(Mouse)
Kowa

Curated by ChEMBL
LigandPNGBDBM50285428(1-{5-[4,5-Bis-(4-methoxy-phenyl)-1H-imidazol-2-yls...)
Affinity DataIC50: 320nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase in J774 Macrophage cell cultureMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSterol O-acyltransferase 1(Mouse)
Kowa

Curated by ChEMBL
LigandPNGBDBM50462680(CHEMBL4238030)
Affinity DataIC50: 350nMAssay Description:Inhibition of ACAT1 in mouse J774 cells assessed as reduction in esterified cholesterol accumulation after 18 hrs in presence of 25-hydroxycholestero...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Mouse)
Kowa

Curated by ChEMBL
LigandPNGBDBM50450348(CHEMBL51282)
Affinity DataIC50: 370nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in J774 Macrophage cell cultureMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details

TargetSterol O-acyltransferase 1(Mouse)
Kowa

Curated by ChEMBL
LigandPNGBDBM50005944(2,2-Dimethyl-dodecanoic acid (2,4,6-trimethoxy-phe...)
Affinity DataIC50: 400nMAssay Description:Compound was tested for its ability to penetrate the cell wall and inhibit macrophage ACAT in cell culture using murine IC-21 macrophages (MAI)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article
PDB3D3D Structure (crystal)
TargetSterol O-acyltransferase 1(Mouse)
Kowa

Curated by ChEMBL
LigandPNGBDBM50462671(CHEMBL4249719)
Affinity DataIC50: 400nMAssay Description:Inhibition of ACAT1 in mouse J774 cells assessed as reduction in esterified cholesterol accumulation after 18 hrs in presence of 25-hydroxycholestero...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Mouse)
Kowa

Curated by ChEMBL
LigandPNGBDBM50462657(CHEMBL4244680)
Affinity DataIC50: 410nMAssay Description:Inhibition of ACAT1 in mouse J774 cells assessed as reduction in esterified cholesterol accumulation after 18 hrs in presence of 25-hydroxycholestero...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Mouse)
Kowa

Curated by ChEMBL
LigandPNGBDBM50462660(CHEMBL4245518)
Affinity DataIC50: 410nMAssay Description:Inhibition of ACAT1 in mouse J774 cells assessed as reduction in esterified cholesterol accumulation after 18 hrs in presence of 25-hydroxycholestero...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Mouse)
Kowa

Curated by ChEMBL
LigandPNGBDBM50450347(CHEMBL431940)
Affinity DataIC50: 450nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in J774 Macrophage cell cultureMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details

TargetSterol O-acyltransferase 1(Mouse)
Kowa

Curated by ChEMBL
LigandPNGBDBM50462679(CHEMBL4244693)
Affinity DataIC50: 460nMAssay Description:Inhibition of ACAT1 in mouse J774 cells assessed as reduction in esterified cholesterol accumulation after 18 hrs in presence of 25-hydroxycholestero...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Mouse)
Kowa

Curated by ChEMBL
LigandPNGBDBM50462708(CHEMBL4243773)
Affinity DataIC50: 470nMAssay Description:Inhibition of ACAT1 in mouse J774 cells assessed as reduction in esterified cholesterol accumulation after 18 hrs in presence of 25-hydroxycholestero...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Mouse)
Kowa

Curated by ChEMBL
LigandPNGBDBM50285425((1H-Benzoimidazol-2-yl)-{5-[4,5-bis-(4-methoxy-phe...)
Affinity DataIC50: 490nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase in J774 Macrophage cell cultureMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSterol O-acyltransferase 1(Mouse)
Kowa

Curated by ChEMBL
LigandPNGBDBM50285424(Benzooxazol-2-yl-{4-[4,5-bis-(4-methoxy-phenyl)-1H...)
Affinity DataIC50: 500nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase in J774 Macrophage cell cultureMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSterol O-acyltransferase 1(Mouse)
Kowa

Curated by ChEMBL
LigandPNGBDBM50285418(Benzooxazol-2-yl-ethyl-{5-[5-(4-methylsulfanyl-phe...)
Affinity DataIC50: 500nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase in J774 Macrophage cell cultureMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSterol O-acyltransferase 1(Mouse)
Kowa

Curated by ChEMBL
LigandPNGBDBM50462699(CHEMBL4245696)
Affinity DataIC50: 500nMAssay Description:Inhibition of ACAT1 in mouse J774 cells assessed as reduction in esterified cholesterol accumulation after 18 hrs in presence of 25-hydroxycholestero...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
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